The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy
Open accessAbstract
Reactive oxygen species (ROS)‐induced apoptosis is a widely practiced strategy for cancer therapy. Although photodynamic therapy (PDT) takes advantage of the spatial–temporal control of ROS generation, the meticulous participation of light, photosensitizer, and oxygen greatly hinders the broad application of PDT as a first‐line cancer treatment option. An activatable system has been developed that enables tumor‐specific singlet oxygen (1 O 2) generation for cancer therapy, based on a Fenton‐like reaction between linoleic acid hydroperoxide (LAHP) tethered on iron oxide nanoparticles (IO NPs) and the released iron(II) ions from IO NPs under acidic‐pH condition. The IO‐LAHP NPs are able to induce efficient apoptotic cancer cell death both in vitro and in vivo through tumor‐specific 1 O 2 generation and subsequent ROS mediated mechanism. This study demonstrates the effectiveness of modulating biochemical reactions as a ROS source to exert cancer death.
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Platelet membrane-camouflaged magnetic nanoparticles for ferroptosis-enhanced cancer immunotherapy
Jiang, Q., Wang, K., Zhang, X., Ouyang, B., Liu, H., Pang, Z., & Yang, W. (2020) · Small · doi:10.1002/smll.202001704 · Cited by 426
Wang, C., Cao, F., Ruan, Y., Jia, X., Zhen, W., & Jiang, X. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201903981 · Cited by 411
Dai, Y., Yang, Z., Cheng, S., Wang, Z., Zhang, R., Zhu, G., Wang, Z., Yung, B. C., Tian, R., Jacobson, O., et al. (2018) · Advanced Materials · doi:10.1002/adma.201704877 · Cited by 409
Self-citationTumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics
Gong, F., Yang, N., Wang, X., Zhao, Q., Chen, Q., Liu, Z., & Cheng, L. (2020) · Nano Today · doi:10.1016/j.nantod.2020.100851 · Cited by 359
Metadata
- Authors
- Zhou, Z., Song, J., Tian, R., Yang, Z., Yu, G., Lin, L., Zhang, G., Fan, W., Zhang, F., Niu, G., Nie, L., & Chen, X.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2017-05-04
- Volume
- 56
- Issue
- 23
- Pages
- 6492-6496
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2611800801
- Cited by
- 387
- References
- 8
- FWCI
- 20.83
- Type
- journal article
- Language
- en
- Open access
- green
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- Zhou, Z., Song, J., Tian, R., Yang, Z., Yu, G., Lin, L., Zhang, G., Fan, W., Zhang, F., Niu, G., Nie, L., & Chen, X. (2017). Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201701181
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