The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Electrochemically Enabled, Nickel‐Catalyzed Amination
Open accessAbstract
Along with amide bond formation, Suzuki cross‐coupling, and reductive amination, the Buchwald–Hartwig–Ullmann‐type amination of aryl halides stands as one of the most employed reactions in modern medicinal chemistry. The work herein demonstrates the potential of utilizing electrochemistry to provide a complementary avenue to access such critical bonds using an inexpensive nickel catalyst under mild reaction conditions. Of note is the scalability, functional‐group tolerance, rapid rate, and the ability to employ a variety of aryl donors (Ar−Cl, Ar−Br, Ar−I, Ar−OTf), amine types (primary and secondary), and even alternative X−H donors (alcohols and amides).
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Cites
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
Ruiz-Castillo, P., & Buchwald, S. L. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00512 · Cited by 2,936
Brown, D. G., & Boström, J. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01409 · Cited by 1,964
Redox catalysis in organic electrosynthesis: basic principles and recent developments
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Hartwig, J. F. (1998) · Angewandte Chemie International Edition · Cited by 1,719
Induced protein degradation: an emerging drug discovery paradigm
Lai, A. C., & Crews, C. M. (2017) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.211 · Cited by 1,486
Modern Strategies in Electroorganic Synthesis
Yoshida, J.-I., Kataoka, K., Horcajada, R., & Nagaki, A. (2008) · Chemical Reviews · doi:10.1021/cr0680843 · Cited by 1,417
Structural basis of PROTAC cooperative recognition for selective protein degradation
Gadd, M. S., Testa, A., Lucas, X., Chan, K.-H., Chen, W., Lamont, D. J., Zengerle, M., & Ciulli, A. (2017) · Nature Chemical Biology · doi:10.1038/nchembio.2329 · Cited by 1,242
Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method
Horn, E. J., Rosen, B. R., & Baran, P. S. (2016) · ACS Central Science · doi:10.1021/acscentsci.6b00091 · Cited by 1,068
Self-citationThe application of cathodic reductions and anodic oxidations in the synthesis of complex molecules
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Aryl amination using ligand-free Ni(II) salts and photoredox catalysis
Corcoran, E. B., Pirnot, M. T., Lin, S., Dreher, S. D., DiRocco, D. A., Davies, I. W., Buchwald, S. L., & MacMillan, D. W. C. (2016) · Science · doi:10.1126/science.aag0209 · Cited by 620
Cited by
Electrifying Organic Synthesis
Wiebe, A., Gieshoff, T., Möhle, S., Rodrigo, E., Zirbes, M., & Waldvogel, S. R. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201711060 · Cited by 1,530
Tay, N. E. S., Lehnherr, D., & Rovis, T. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00384 · Cited by 518
New Redox Strategies in Organic Synthesis by Means of Electrochemistry and Photochemistry
Liu, J., Lu, L., Wood, D., & Lin, S. (2020) · ACS Central Science · doi:10.1021/acscentsci.0c00549 · Cited by 470
Synthetic Photoelectrochemistry
Barham, J. P., & König, B. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201913767 · Cited by 448
Zaera, F. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00905 · Cited by 425
Metadata
- Authors
- Li, C., Kawamata, Y., Nakamura, H., Vantourout, J. C., Liu, Z., Hou, Q., Bao, D., Starr, J. T., Chen, J., Yan, M., & Baran, P. S.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2017-09-14
- Volume
- 56
- Issue
- 42
- Pages
- 13088-13093
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2746093901
- Cited by
- 316
- References
- 20
- FWCI
- 15.15
- Type
- journal article
- Language
- en
- Open access
- green
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- Li, C., Kawamata, Y., Nakamura, H., Vantourout, J. C., Liu, Z., Hou, Q., Bao, D., Starr, J. T., Chen, J., Yan, M., & Baran, P. S. (2017). Electrochemically Enabled, Nickel‐Catalyzed Amination. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201707906
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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