The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A Multi‐signal Fluorescent Probe with Multiple Binding Sites for Simultaneous Sensing of Cysteine, Homocysteine, and Glutathione
Abstract
A novel fluorescent probe was developed by integrating chlorinated coumarin and benzothiazolylacetonitrile and exploited for simultaneous detection of cysteine (Cys), homocysteine (Hcy), and glutathione (GSH). Featuring four binding sites and different reaction mechanisms for different biothiols, this probe exhibited rapid fluorescence turn‐on for distinguishing Cys, Hcy, and GSH with 108‐, 128‐, 30‐fold fluorescence increases at 457, 559, 529 nm, respectively, across different excitation wavelengths. Furthermore, the probe was successfully applied to the fluorescence imaging of endogenous Cys and GSH and exogenous Cys, Hcy, and GSH in living cells.
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Cites
Oxidized Redox State of Glutathione in the Endoplasmic Reticulum
Hwang, C., Sinskey, A. J., & Lodish, H. F. (1992) · Science · doi:10.1126/science.1523409 · Cited by 1,968
Fluorescent and colorimetric probes for detection of thiols
Chen, X., Zhou, Y., Peng, X., & Yoon, J. (2010) · Chemical Society Reviews · doi:10.1039/b925092a · Cited by 1,580
Cited by
Zeng, S., Liu, X., Kafuti, Y. S., Kim, H., Wang, J., Peng, X., Li, H., & Yoon, J. (2023) · Chemical Society Reviews · doi:10.1039/d2cs00799a · Cited by 341
Self-citationQin, Z., Ren, T., Zhou, H., Zhang, X., He, L., Li, Z., Zhang, X., & Yuan, L. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202201541 · Cited by 140
Pan, Y., Lei, S., Zhang, J., Qu, J., Huang, P., & Lin, J. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.1c04504 · Cited by 45
Metadata
- Authors
- Yin, G., Niu, T., Gan, Y., Yu, T., Yin, P., Chen, H., Zhang, Y., Li, H., & Yao, S.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2018-03-23
- Volume
- 57
- Issue
- 18
- Pages
- 4991-4994
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2793791636
- Cited by
- 314
- References
- 2
- FWCI
- 13.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yin, G., Niu, T., Gan, Y., Yu, T., Yin, P., Chen, H., Zhang, Y., Li, H., & Yao, S. (2018). A Multi‐signal Fluorescent Probe with Multiple Binding Sites for Simultaneous Sensing of Cysteine, Homocysteine, and Glutathione. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201800485
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