The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A Single‐Atom Nanozyme for Wound Disinfection Applications
Abstract
Single‐atom catalysts (SACs), as homogeneous catalysts, have been widely explored for chemical catalysis. However, few studies focus on the applications of SACs in enzymatic catalysis. Herein, we report that a zinc‐based zeolitic‐imidazolate‐framework (ZIF‐8)‐derived carbon nanomaterial containing atomically dispersed zinc atoms can serve as a highly efficient single‐atom peroxidase mimic. To reveal its structure–activity relationship, the structural evolution of the single‐atom nanozyme (SAzyme) was systematically investigated. Furthermore, the coordinatively unsaturated active zinc sites and catalytic mechanism of the SAzyme are disclosed using density functional theory (DFT) calculations. The SAzyme, with high therapeutic effect and biosafety, shows great promises for wound antibacterial applications.
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Cites
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
Self-citationCatalysis by Supported Single Metal Atoms
Liu, J. (2017) · ACS Catalysis · doi:10.1021/acscatal.6b01534 · Cited by 1,331
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Liang, Y., He, J., & Guo, B. (2021) · ACS Nano · doi:10.1021/acsnano.1c04206 · Cited by 3,135
Yang, B., Chen, Y., & Shi, J. (2019) · Advanced Materials · doi:10.1002/adma.201901778 · Cited by 601
Inorganic nanomaterials with rapid clearance for biomedical applications
Wang, X., Zhong, X., Li, J., Liu, Z., & Cheng, L. (2021) · Chemical Society Reviews · doi:10.1039/d0cs00461h · Cited by 509
Metal‐Nitrogen‐Doped Carbon Materials as Highly Efficient Catalysts: Progress and Rational Design
Shi, Z., Yang, W., Gu, Y., Liao, T., & Sun, Z. (2020) · Advanced Science · doi:10.1002/advs.202001069 · Cited by 470
A Nanozyme with Photo‐Enhanced Dual Enzyme‐Like Activities for Deep Pancreatic Cancer Therapy
Li, S., Shang, L., Xu, B., Wang, S., Gu, K., Wu, Q., Sun, Y., Zhang, Q., Yang, H., Zhang, F., et al. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201904751 · Cited by 466
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Metadata
- Authors
- Xu, B., Wang, H., Wang, W., Gao, L., Li, S., Pan, X., Wang, H., Yang, H., Meng, X., Wu, Q., Zheng, L., Chen, S., Shi, X., Fan, K., Yan, X., & Liu, H.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2019-03-05
- Volume
- 58
- Issue
- 15
- Pages
- 4911-4916
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2913427693
- Cited by
- 860
- References
- 2
- FWCI
- 36.39
- Type
- journal article
- Language
- en
- Open access
- closed
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- Xu, B., Wang, H., Wang, W., Gao, L., Li, S., Pan, X., Wang, H., Yang, H., Meng, X., Wu, Q., Zheng, L., Chen, S., Shi, X., Fan, K., Yan, X., & Liu, H. (2019). A Single‐Atom Nanozyme for Wound Disinfection Applications. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201813994
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