The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
A Nanozyme with Photo‐Enhanced Dual Enzyme‐Like Activities for Deep Pancreatic Cancer Therapy
Abstract
Nanozymes have attracted extensive interest owing to their high stability, low cost and easy preparation, especially in the field of cancer therapy. However, the relatively low catalytic activity of nanozymes in the tumor microenvironment (TME) has limited their applications. Herein, we report a novel nanozyme (PtFe@Fe 3 O 4) with dual enzyme‐like activities for highly efficient tumor catalytic therapy. PtFe@Fe 3 O 4 shows the intrinsic photothermal effect as well as photo‐enhanced peroxidase‐like and catalase‐like activities in the acidic TME, thereby effectively killing tumor cells and overcoming the tumor hypoxia. Importantly, a possible photo‐enhanced synergistic catalytic mechanism of PtFe@Fe 3 O 4 was first disclosed. We believe that this work will advance the development of nanozymes in tumor catalytic therapy.
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Self-citationNanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
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Cited by
Nanozymes: Activity origin, catalytic mechanism, and biological application
Yang, W., Yang, X., Zhu, L., Chu, H., Li, X., & Xu, W. (2021) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2021.214170 · Cited by 470
Immunomodulation‐Enhanced Nanozyme‐Based Tumor Catalytic Therapy
Xu, B., Cui, Y., Wang, W., Li, S., Lyu, C., Wang, S., Bao, W., Wang, H., Qin, M., Liu, Z., et al. (2020) · Advanced Materials · doi:10.1002/adma.202003563 · Cited by 404
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A pH-activated autocatalytic nanoreactor for self-boosting Fenton-like chemodynamic therapy
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Metadata
- Authors
- Li, S., Shang, L., Xu, B., Wang, S., Gu, K., Wu, Q., Sun, Y., Zhang, Q., Yang, H., Zhang, F., Gu, L., Zhang, T., & Liu, H.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2019-08-02
- Volume
- 58
- Issue
- 36
- Pages
- 12624-12631
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2955231196
- Cited by
- 466
- References
- 48
- FWCI
- 22.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, S., Shang, L., Xu, B., Wang, S., Gu, K., Wu, Q., Sun, Y., Zhang, Q., Yang, H., Zhang, F., Gu, L., Zhang, T., & Liu, H. (2019). A Nanozyme with Photo‐Enhanced Dual Enzyme‐Like Activities for Deep Pancreatic Cancer Therapy. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201904751
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