The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
Selective Arene Hydrogenation for Direct Access to Saturated Carbo‐ and Heterocycles
Open accessAbstract
Arene hydrogenation provides direct access to saturated carbo‐ and heterocycles and thus its strategic application may be used to shorten synthetic routes. This powerful transformation is widely applied in industry and is expected to facilitate major breakthroughs in the applied sciences. The ability to overcome aromaticity while controlling diastereo‐, enantio‐, and chemoselectivity is central to the use of hydrogenation in the preparation of complex molecules. In general, the hydrogenation of multisubstituted arenes yields predominantly the cis isomer. Enantiocontrol is imparted by chiral auxiliaries, Brønsted acids, or transition‐metal catalysts. Recent studies have demonstrated that highly chemoselective transformations are possible. Such methods and the underlying strategies are reviewed herein, with an emphasis on synthetically useful examples that employ readily available catalysts.
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Cited by
Cabré, A., Verdaguer, X., & Riera, A. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00496 · Cited by 477
Chiral phosphoric acid-catalyzed asymmetric dearomatization reactions
Xia, Z.-L., Xu-Xu, Q.-F., Zheng, C., & You, S.-L. (2020) · Chemical Society Reviews · doi:10.1039/c8cs00436f · Cited by 398
Metadata
- Authors
- Wiesenfeldt, M. P., Nairoukh, Z., Dalton, T., & Glorius, F.
- Venue
- Angewandte Chemie International Edition
- Publisher
- Wiley
- Published
- 2019-04-29
- Volume
- 58
- Issue
- 31
- Pages
- 10460-10476
- ISSN
- 1433-7851 (ISSN-L)
- 1521-3773
- OpenAlex
- W2913761448
- Cited by
- 326
- References
- 61
- FWCI
- 12.52
- Type
- journal article
- Language
- en
- Open access
- hybrid
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