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Cited by 394

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

Mo2C‐Derived Polyoxometalate for NIR‐II Photoacoustic Imaging‐Guided Chemodynamic/Photothermal Synergistic Therapy

Liu, Gongyuan, Zhu, Jiawei, Guo, Heng, Sun, Aihui, Chen, Peng, Xi, Lei, Huang, Wei, Song, Xuejiao, Dong, Xiaochen·2019·Angewandte Chemie International Edition

Abstract

To overcome the current limitations of chemodynamic therapy (CDT), a Mo 2 C‐derived polyoxometalate (POM) is readily synthesized as a new CDT agent. It permits synergistic chemodynamic and photothermal therapy operating in the second near‐infrared (NIR‐II) biological transparent window for deep tissue penetration. POM aggregated in an acidic tumor micro‐environment (TME) whereby enables specific tumor targeting. In addition to the strong ability to produce singlet oxygen (1 O 2) presumably via Russell mechanism, its excellent photothermal conversion enhances the CDT effect, offers additional tumor ablation modality, and permits NIR‐II photoacoustic imaging. Benefitting from the reversible redox property of molybdenum, the theranostics based on POM can escape from the antioxidant defense system. Moreover, combining the specific responsiveness to TME and localized laser irradiation, side‐effects shall be largely avoided.

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Metadata

Authors
Liu, G., Zhu, J., Guo, H., Sun, A., Chen, P., Xi, L., Huang, W., Song, X., & Dong, X.
Venue
Angewandte Chemie International Edition
Publisher
Wiley
Published
2019-10-31
Volume
58
Issue
51
Pages
18641-18646
ISSN
  • 1433-7851 (ISSN-L)
  • 1521-3773
OpenAlex
W2979380254
Cited by
394
References
35
FWCI
16.42
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Mo2C‐Derived Polyoxometalate for NIR‐II Photoacoustic Imaging‐Guided Chemodynamic/Photothermal Synergistic Therapy. https://app.cochat.ai/papers/10.1002/anie.201910815
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Liu, G., Zhu, J., Guo, H., Sun, A., Chen, P., Xi, L., Huang, W., Song, X., & Dong, X. (2019). Mo2C‐Derived Polyoxometalate for NIR‐II Photoacoustic Imaging‐Guided Chemodynamic/Photothermal Synergistic Therapy. Angewandte Chemie International Edition. https://doi.org/10.1002/anie.201910815

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