The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
An autoradiographic study of the mouse olfactory epithelium: Evidence for long‐lived receptors
Abstract
In order to try to determine whether differentiated olfactory receptors turn over (die and are replaced by newly differentiated cells) during adult life, mice were injected with a single dose of 3 H‐thymidine at either 2 or 4 months of age and allowed to survive for up to 12 months; they were caged in a laminar flow unit to prevent rhinitis. Counts of labeled receptor cells detected autoradiographically after injection at 2 months of age revealed that, following an initial decrease from 1 to 3 months of survival, numbers of labeled cells remained approximately constant, at least up to 12 months of survival. Cells still labeled at 12 months of survival were confirmed as receptor cells by electron microscopic examination of reembedded sections. The hypothesis is suggested that in the absence of disease‐related destruction of the olfactory epithelium, most or all receptor cell turnover represents newly formed cells that fail to establish synapses with the olfactory bulb; fully differentiated receptor cells may be quite long‐lived.
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Harkema, J. R., Carey, S. A., & Wagner, J. G. (2006) · Toxicologic Pathology · doi:10.1080/01926230600713475 · Cited by 511
Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells
Bohórquez, D. V., Shahid, R. A., Erdmann, A., Kreger, A. M., Wang, Y., Calakos, N., Wang, F., & Liddle, R. A. (2015) · Journal of Clinical Investigation · doi:10.1172/jci78361 · Cited by 484
Olfaction in Parkinson's disease and related disorders
Doty, R. L. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.10.026 · Cited by 431
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Verhaagen, J., Oestreicher, A., Gispen, W., & Margolis, F. (1989) · The Journal of Neuroscience · doi:10.1523/jneurosci.09-02-00683.1989 · Cited by 309
Metadata
- Authors
- Hinds, J. W., Hinds, P. L., & McNelly, N. A.
- Venue
- The Anatomical Record
- Publisher
- Wiley
- Published
- 1984-10
- Volume
- 210
- Issue
- 2
- Pages
- 375-383
- ISSN
- 0003-276X (ISSN-L)
- 1097-0185
- OpenAlex
- W2001534443
- Cited by
- 271
- References
- 11
- FWCI
- 4.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hinds, J. W., Hinds, P. L., & McNelly, N. A. (1984). An autoradiographic study of the mouse olfactory epithelium: Evidence for long‐lived receptors. The Anatomical Record. https://doi.org/10.1002/ar.1092100213
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
