The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Gastrointestinal motility disorders in scleroderma
Abstract
After the skin, the gastrointestinal tract is the second most common target of systemic sclerosis. The major clinical manifestations include gastroesophageal reflux, small bowel bacterial overgrowth, malnutrition, and intestinal pseudoobstruction. Treatment is symptomatic and supportive. Gastroesophageal reflux can usually be adequately managed with prokinetic drugs, omeprazole, and judicious use of antireflux surgery. If Barrett's esophagus is present, periodic endoscopic monitoring for development of dysplastic changes or adenocarcinoma is indicated. Bacterial overgrowth usually responds to rotating antibiotics and prokinetic drugs. Malnutrition and intestinal pseudoobstruction remain the major problems and often home total parenteral nutrition is required. Intestinal pseudoobstruction occurs in two phases: an early, neuropathic phase may respond to prokinetic drugs (metoclopramide, cisapride, octreotide, and erythromycin) and dietary modification (low-residue diets, vitamin supplementation). In the late myopathic phase, therapy is usually ineffective. Treatment consists of nutritional support. Careful manometric and radiographic localization of affected segments of stomach and small and large intestines may allow judicious surgical resection or venting procedures to reduce symptoms in this unfortunate group of patients.
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Cites
Scleroderma (systemic sclerosis): classification, subsets and pathogenesis
(2001) · Classic Papers in Rheumatology · doi:10.3109/9780203214237-95 · Cited by 3,950
Pathologic observations in systemic sclerosis (scleroderma)
D'Angelo, W. A., Fries, J. F., Masi., A. T., & Shulman, L. E. (1969) · The American Journal of Medicine · doi:10.1016/0002-9343(69)90044-8 · Cited by 1,111
Simplified assessment of segmental colonic transit
Metcalf, A. M., Phillips, S. F., Zinsmeister, A. R., MacCarty, R. L., Beart, R. W., & Wolff, B. G. (1987) · Gastroenterology · doi:10.1016/0016-5085(87)90837-7 · Cited by 928
Vantrappen, G., Janssens, J., Hellemans, J., & Ghoos, Y. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108740 · Cited by 815
Improvement of Gastric Emptying in Diabetic Gastroparesis by Erythromycin: Preliminary Studies
Janssens, J., Peeters, T. L., Vantrappen, G., Tack, J., Urbain, J. L., De Roo, M., Muls, E., & Bouillon, R. (1990) · New England Journal of Medicine · doi:10.1056/nejm199004123221502 · Cited by 753
Effect of Octreotide on Intestinal Motility and Bacterial Overgrowth in Scleroderma
Soudah, H. C., Hasler, W. L., & Owyang, C. (1991) · New England Journal of Medicine · doi:10.1056/nejm199111213252102 · Cited by 414
Abnormal intestinal motility in diabetics with the gastroparesis syndrome
CAMILLERI, M., & MALAGELADA, J. (1984) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.1984.tb01206.x · Cited by 328
Effect of eating and gastrointestinal hormones on human colonic myoelectrical and motor activity
Snape, W. J., Matarazzo, S. A., & Cohen, S. (1978) · Gastroenterology · doi:10.1016/0016-5085(78)90835-1 · Cited by 247
The gastrointestinal manifestations of scleroderma: Pathogenesis and management
Cohen, S., Laufer, I., Snape, W. J., Shiau, Y.-F., Levine, G. M., & Jimenez, S. (1980) · Gastroenterology · doi:10.1016/0016-5085(80)90091-8 · Cited by 224
Effect of six weeks of treatment with cisapride in gastroparesis and intestinal pseudoobstruction
Camilleri, M., Malagelada, J.-R., Abell, T. L., Brown, M. L., Hench, V., & Zinsmeister, A. R. (1989) · Gastroenterology · doi:10.1016/0016-5085(89)90893-7 · Cited by 199
Cited by
Gastroesophageal Reflux and Pulmonary Fibrosis in Scleroderma: A Study Using pH-Impedance Monitoring
Savarino, E., Bazzica, M., Zentilin, P., Pohl, D., Parodi, A., Cittadini, G., Negrini, S., Indiveri, F., Tutuian, R., Savarino, V., et al. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200808-1359oc · Cited by 269
Clinical and Upper Gastrointestinal Motility Features in Systemic Sclerosis and Related Disorders
Weston, S., Thumshirn, M., Wiste, J., & Camilleri, M. (1998) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1998.00334.x · Cited by 186
Gastrointestinal complications: the most frequent internal complications of systemic sclerosis
Forbes, A., & Marie, I. (2009) · Rheumatology · doi:10.1093/rheumatology/ken485 · Cited by 162
Manetti, M., Neumann, E., Milia, A. F., Tarner, I. H., Bechi, P., Matucci‐Cerinic, M., Ibba‐Manneschi, L., & Müller‐Ladner, U. (2007) · Arthritis & Rheumatism · doi:10.1002/art.22940 · Cited by 82
Metadata
- Authors
- Sjogren, R. W.
- Venue
- Arthritis & Rheumatism
- Publisher
- Wiley
- Published
- 1994-08
- Volume
- 37
- Issue
- 9
- Pages
- 1265-1282
- ISSN
- 0004-3591 (ISSN-L)
- 1529-0131
- OpenAlex
- W2013117232
- Cited by
- 381
- References
- 47
- FWCI
- 5.29
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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