The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies
Abstract
While an evaluation of the estrous cycle in laboratory rodents can be a useful measure of the integrity of the hypothalamic‐pituitary‐ovarian reproductive axis, it can also serve as a way of insuring that animals exhibiting abnormal cycling patterns are disincluded from a study prior to exposure to a test compound. Assessment of vaginal cytology in regularly cycling animals also provides a means to establish a comparable endocrine milieu for animals at necropsy. The procedure for obtaining a vaginal smear is relatively non‐invasive and is one to which animals can become readily accustomed. It requires few supplies, and with some experience the assessments can be easily performed in fresh, unstained smears, or in fixed, stained ones. When incorporated as an adjunct to other endpoint measures, a determination of a female's cycling status can contribute important information about the nature of a toxicant insult to the reproductive system. In doing so, it can help to integrate the data into a more comprehensive mechanistic portrait of the effect, and in terms of risk assessment, may provide some indication of a toxicant's impact on human reproductive physiology. Birth Defects Res (Part B), 2007. Published 2007 Wiley‐Liss, Inc.
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Cites
Estrogenic Activity of Octylphenol, Nonylphenol, Bisphenol A and Methoxychlor in Rats
Laws, S. C. (2000) · Toxicological Sciences · doi:10.1093/toxsci/54.1.154 · Cited by 545
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Stockard, C. R., & Papanicolaou, G. N. (1917) · American Journal of Anatomy · doi:10.1002/aja.1000220204 · Cited by 471
Pesticide exposure: the hormonal function of the female reproductive system disrupted?
Bretveld, R. W., Thomas, C. M., Scheepers, P. T., Zielhuis, G. A., & Roeleveld, N. (2006) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-4-30 · Cited by 344
The cooperative solving of problems by young chimpanzees
Crawford, M. (1937) · Biodiversity Heritage Library (Smithsonian Institution) · Cited by 266
BRAWER, J. R., NAFTOLIN, F., MARTIN, J., & SONNENSCHEIN, C. (1978) · Endocrinology · doi:10.1210/endo-103-2-501 · Cited by 225
Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide
Mayer, L. P., Pearsall, N. A., Christian, P. J., Devine, P. J., Payne, C. M., McCuskey, M. K., Marion, S. L., Sipes, I. G., & Hoyer, P. B. (2002) · Reproductive Toxicology · doi:10.1016/s0890-6238(02)00048-5 · Cited by 162
The Phases of the Oestrous Cycle in the Adult White Rat
Mandl, A. M. (1951) · Journal of Experimental Biology · doi:10.1242/jeb.28.4.576 · Cited by 154
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Dumais, K. M., & Veenema, A. H. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2015.04.003 · Cited by 520
“V1aR binding densities were analyzed in non-estrus and estrus Wistar ristics defined by Goldman et al. (2007). Rats were categorized as being in proestrus/ her levels of estradiol and progesterone) or in non-estrus (n = 15; cells characteristic of V1aR binding densities were also analyzed in virgin (nulliparous, n = 1…”
MethodHanamsagar, R., Alter, M. D., Block, C. S., Sullivan, H., Bolton, J. L., & Bilbo, S. D. (2017) · Glia · doi:10.1002/glia.23176 · Cited by 384
Sexual dimorphic pattern of renal transporters and electrolyte homeostasis
Veiras, L. C., Girardi, A. C. C., Curry, J., Pei, L., Ralph, D. L., Tran, A., Castelo-Branco, R. C., Pastor-Soler, N., Arranz, C. T., Yu, A. S. L., et al. (2017) · Journal of the American Society of Nephrology · doi:10.1681/asn.2017030295 · Cited by 316
Modeling menopause: The utility of rodents in translational behavioral endocrinology research
Koebele, S. V., & Bimonte-Nelson, H. A. (2016) · Maturitas · doi:10.1016/j.maturitas.2016.01.015 · Cited by 293
Kopec, A. M., Smith, C. J., Ayre, N. R., Sweat, S. C., & Bilbo, S. D. (2018) · Nature Communications · doi:10.1038/s41467-018-06118-z · Cited by 258
Metadata
- Authors
- Goldman, J. M., Murr, A. S., & Cooper, R. L.
- Venue
- Birth Defects Research Part B: Developmental and Reproductive Toxicology
- Publisher
- Wiley
- Published
- 2007-03-06
- Volume
- 80
- Issue
- 2
- Pages
- 84-97
- ISSN
- 1542-9733 (ISSN-L)
- 1542-9741
- OpenAlex
- W2061310823
- Cited by
- 801
- References
- 45
- FWCI
- 11.84
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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