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Cited by 502

The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.

The pleiotropic functions of the Y‐box‐binding protein, YB‐1

Kohno, Kimitoshi, Izumi, Hiroto, Uchiumi, Takeshi, Ashizuka, Megumi, Kuwano, Michihiko·2003·BioEssays

Abstract

The Y‐box‐binding protein (YB‐1) represents the most evolutionary conserved nucleic‐acid‐binding protein currently known. YB‐1 is a member of the cold‐shock domain (CSD) protein superfamily. It performs a wide variety of cellular functions, including transcriptional regulation, translational regulation, DNA repair, drug resistance and stress responses to extracellular signals. As a result, YB‐1 expression is closely associated with cell proliferation. In this review, we will begin by briefly describing the characteristics of YB‐1 and will then summarize the pleiotropic functions brought about via DNA–RNA transaction and protein–protein interactions. In addition, we will discuss the diverse range of potential physiological and pathological functions of YB‐1. BioEssays 25:691–698, 2003. © 2003 Wiley Periodicals, Inc.

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Crossref · 10.1002/bies.10300

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Metadata

Authors
Kohno, K., Izumi, H., Uchiumi, T., Ashizuka, M., & Kuwano, M.
Venue
BioEssays
Publisher
Wiley
Published
2003-06-13
Volume
25
Issue
7
Pages
691-698
ISSN
  • 0265-9247 (ISSN-L)
  • 1521-1878
OpenAlex
W1995333503
Cited by
502
References
64
FWCI
1.57
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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