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The flavonoid biosynthetic pathway in plants: Function and evolution
Abstract
Flavonoids are a class of low molecular weight phenolic compounds that is widely distributed in the plant kingdom. They exhibit a diverse spectrum of biological functions and play an important role in the interaction between plants and their environment. Flavonoids not only protect the plant from the harmful effects of UV irradiation but also play a crucial role in the sexual reproduction process. A special class of flavonoid polymers, the tannins, plays a structural role in the plant. Yet other classes of flavonoids, flavonols and anthocyanins, have been implicated in the attraction of pollinators. Certain flavonoids participate in the interaction between plants and other organisms such as symbiotic bacteria and parasites. This raises the intriguing question as to how these different compounds arose and evolved. Based on taxonomy and molecular analysis of gene expression patterns it is possible to deduce a putative sequence of acquisition of the different branches of the biosynthetic pathway and their regulators.
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Cites
Lerouge, P., Roche, P., Faucher, C., Maillet, F., Truchet, G., Promé, J. C., & Dénarié, J. (1990) · Nature · doi:10.1038/344781a0 · Cited by 1,166
A Plant Flavone, Luteolin, Induces Expression of Rhizobium meliloti Nodulation Genes
Peters, N. K., Frost, J. W., & Long, S. R. (1986) · Science · doi:10.1126/science.3738520 · Cited by 972
Arabidopsis Flavonoid Mutants Are Hypersensitive to UV-B Irradiation.
Li, J., Ou-Lee, T. M., Raba, R., Amundson, R. G., & Last, R. L. (1993) · The Plant Cell · doi:10.1105/tpc.5.2.171 · Cited by 937
Signals and transduction mechanisms for activation of plant defenses against microbial attack
Lamb, C. J., Lawton, M. A., Dron, M., & Dixon, R. A. (1989) · Cell · doi:10.1016/0092-8674(89)90894-5 · Cited by 737
Naturally Occurring Auxin Transport Regulators
Jacobs, M., & Rubery, P. H. (1988) · Science · doi:10.1126/science.241.4863.346 · Cited by 631
Rhizobium–plant signal exchange
Fisher, R. F., & Long, S. R. (1992) · Nature · doi:10.1038/357655a0 · Cited by 617
GENETIC AND DEVELOPMENTAL CONTROL OF ANTHOCYANIN BIOSYNTHESIS
Dooner, H. K., Robbins, T. P., & Jorgensen, R. A. (1991) · Annual Review of Genetics · doi:10.1146/annurev.ge.25.120191.001133 · Cited by 609
Spaink, H. P., Sheeley, D. M., van Brussel, A. A. N., Glushka, J., York, W. S., Tak, T., Geiger, O., Kennedy, E. P., Reinhold, V. N., & Lugtenberg, B. J. J. (1991) · Nature · doi:10.1038/354125a0 · Cited by 532
Mo, Y., Nagel, C., & Taylor, L. P. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.15.7213 · Cited by 464
An Arabidopsis mutant defective in the general phenylpropanoid pathway.
Chapple, C. C., Vogt, T., Ellis, B. E., & Somerville, C. R. (1992) · The Plant Cell · doi:10.1105/tpc.4.11.1413 · Cited by 445
Control of anthocyanin biosynthesis in flowers of Antirrhinum majus.
Martin, C., Prescott, A., Mackay, S., Bartlett, J., & Vrijlandt, E. (1991) · The Plant Journal · doi:10.1046/j.1365-313x.1991.t01-14-00999.x · Cited by 424
Quattrocchio, F., Wing, J. F., Leppen, H., Mol, J., & Koes, R. E. (1993) · The Plant Cell · doi:10.1105/tpc.5.11.1497 · Cited by 417
Self-citationTHE PROTECTIVE FUNCTION OF THE EPIDERMAL LAYER OF RYE SEEDLINGS AGAINST ULTRAVIOLET‐B RADIATION
TEVINI, M., BRAUN, J., & FIESER, G. (1991) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1991.tb03636.x · Cited by 382
Ultraviolet Radiation and Plants: Burning Questions.
Stapleton, A. E. (1992) · The Plant Cell · doi:10.1105/tpc.4.11.1353 · Cited by 375
THE PHYTOALEXIN RESPONSE: ELICITATION, SIGNALLING AND CONTROL OF HOST GENE EXPRESSION
DIXON, R. A. (1986) · Biological Reviews · doi:10.1111/j.1469-185x.1986.tb00719.x · Cited by 374
Phytoalexin Synthesis: The Biochemical Analysis of the Induction Process
Ebel, J. (1986) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.24.1.235 · Cited by 374
Early nodulin genes are induced in alfalfa root outgrowths elicited by auxin transport inhibitors
Hirsch, A. M., Bhuvaneswari, T. V., Torrey, J. G., & Bisseling, T. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.4.1244 · Cited by 368
Flavonoid activation of nodulation genes in Rhizobium reversed by other compounds present in plants
Firmin, J. L., Wilson, K. E., Rossen, L., & Johnston, A. W. B. (1986) · Nature · doi:10.1038/324090a0 · Cited by 367
van Brussel, A. A. N., Bakhuizen, R., van Spronsen, P. C., Spaink, H. P., Tak, T., Lugtenberg, B. J. J., & Kijne, J. W. (1992) · Science · doi:10.1126/science.257.5066.70 · Cited by 333
Regulation of Flavonoid Biosynthetic Genes in Germinating Arabidopsis Seedlings.
Kubasek, W. L., Shirley, B. W., McKillop, A., Goodman, H. M., Briggs, W., & Ausubel, F. M. (1992) · The Plant Cell · doi:10.1105/tpc.4.10.1229 · Cited by 332
A common gene regulates pigmentation pattern in diverse plant species
Goodrich, J., Carpenter, R., & Coen, E. S. (1992) · Cell · doi:10.1016/0092-8674(92)90038-e · Cited by 332
Flavonoid Evolution: An Enzymic Approach
Stafford, H. A. (1991) · Plant Physiology · doi:10.1104/pp.96.3.680 · Cited by 323
Antisense inhibition of flavonoid biosynthesis in petunia anthers results in male sterility.
van der Meer, I. M., Stam, M. E., van Tunen, A. J., Mol, J. N., & Stuitje, A. R. (1992) · The Plant Cell · doi:10.1105/tpc.4.3.253 · Cited by 317
Self-citationvan Tunen, A. J., Koes, R. E., Spelt, C. E., van der Krol, A. R., Stuitje, A. R., & Mol, J. N. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb02939.x · Cited by 295
Self-citationBeld, M., Martin, C., Huits, H., Stuitje, A. R., & Gerats, A. G. M. (1989) · Plant Molecular Biology · doi:10.1007/bf00027309 · Cited by 265
Goff, S. A., Klein, T. M., Roth, B. A., Fromm, M. E., Cone, K. C., Radicella, J. P., & Chandler, V. L. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07431.x · Cited by 256
Djordjevic, M. A., Redmond, J. W., Batley, M., & Rolfe, B. G. (1987) · The EMBO Journal · doi:10.1002/j.1460-2075.1987.tb02351.x · Cited by 245
Structural basis of blue-colour development in flower petals from Commelina communis
Hondo, T., Yoshida, K., Nakagawa, A., Kawai, T., Tamura, H., & Goto, T. (1992) · Nature · doi:10.1038/358515a0 · Cited by 239
(1985) · Antiviral Research · doi:10.1016/0166-3542(85)90022-1 · Cited by 217
Phenolic Signals In Cohabitation: Implications For Plant Development
Lynn, D. (1990) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.41.1.497 · Cited by 202
The Adaptive Nature of Floral Traits: Ideas and Eviaence
WASER, N. M. (1983) · Pollination Biology · doi:10.1016/b978-0-12-583980-8.50017-x · Cited by 198
Zaat, S. A., Wijffelman, C. A., Spaink, H. P., van Brussel, A. A., Okker, R. J., & Lugtenberg, B. J. (1987) · Journal of Bacteriology · doi:10.1128/jb.169.1.198-204.1987 · Cited by 162
Pollinator behaviour and natural selection for flower colour in Delphinium nelsonii
Waser, N. M., & Price, M. V. (1983) · Nature · doi:10.1038/302422a0 · Cited by 150
Baker, M. E., & Blasco, R. (1992) · FEBS Letters · doi:10.1016/0014-5793(92)80216-4 · Cited by 113
Genetic interactions underlying flower color patterns in Antirrhinum majus.Preprint
Almeida, J., Carpenter, R., Robbins, T. P., Martin, C. R., & Coen, E. (1989) · Genes & Development · doi:10.1101/gad.3.11.1758 · Cited by 100
Pollen- and anther-specific chi promoters from petunia: tandem promoter regulation of the chiA gene.
van Tunen, A. J., Mur, L. A. J., Brouns, G. S., Rienstra, J. D., Koes, R. E., & Mol, J. N. M. (1990) · The Plant Cell · doi:10.1105/tpc.2.5.393 · Cited by 99
Self-citationVerwoert, I. I. G. S., Verbree, E. C., Lindén, K., Nijkamp, H. J. J., & Stuitje, A. R. (1992) · Journal of Bacteriology · doi:10.1128/jb.174.9.2851-2857.1992 · Cited by 83
Swain, T. (1986) · PubMed · Cited by 29
Cited by
Flavonoids: a colorful model for the regulation and evolution of biochemical pathways
Koes, R., Verweij, W., & Quattrocchio, F. (2005) · Trends in Plant Science · doi:10.1016/j.tplants.2005.03.002 · Cited by 1,640
Self-citationHow genes paint flowers and seeds
Mol, J., Grotewold, E., & Koes, R. (1998) · Trends in Plant Science · doi:10.1016/s1360-1385(98)01242-4 · Cited by 848
Self-citationDowney, M. O., Dokoozlian, N. K., & Krstic, M. P. (2006) · American Journal of Enology and Viticulture · doi:10.5344/ajev.2006.57.3.257 · Cited by 758
Nesi, N., Debeaujon, I., Jond, C., Pelletier, G., Caboche, M., & Lepiniec, L. (2000) · The Plant Cell · doi:10.1105/tpc.12.10.1863 · Cited by 747
Ultraviolet radiation screening compounds
COCKELL, C. S., & KNOWLAND, J. (1999) · Biological Reviews of the Cambridge Philosophical Society · doi:10.1017/s0006323199005356 · Cited by 744
Metadata
- Authors
- Koes, R. E., Quattrocchio, F., & Mol, J. N. M.
- Venue
- BioEssays
- Publisher
- Wiley
- Published
- 1994-02
- Volume
- 16
- Issue
- 2
- Pages
- 123-132
- ISSN
- 0265-9247 (ISSN-L)
- 1521-1878
- OpenAlex
- W1991721460
- Cited by
- 768
- References
- 38
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- closed
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