The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Lens development and crystallin gene expression: many roles for Pax‐6
Abstract
The vertebrate eye lens has been used extensively as a model for developmental processes such as determination, embryonic induction, cellular differentiation, transdifferentiation and regeneration, with the crystallin genes being a prime example of developmentally controlled, tissue‐preferred gene expression. Recent studies have shown that Pax‐6, a transcription factor containing both a paired domain and homeodomain, is a key protein regulating lens determination and crystallin gene expression in the lens. The use of Pax‐6 for expression of different crystallin genes provides a new link at the developmental and transcriptional level among the diverse crystallins and may lead to new insights into their evolutionary recruitment as refractive proteins.
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Cites
Homology of the eyeless Gene of Drosophila to the Small eye Gene in Mice and Aniridia in Humans
Quiring, R., Walldorf, U., Kloter, U., & Gehring, W. J. (1994) · Science · doi:10.1126/science.7914031 · Cited by 1,100
Cited by
Xu, P.-X., Woo, I., Her, H., Beier, D. R., & Maas, R. L. (1997) · Development · doi:10.1242/dev.124.1.219 · Cited by 331
The last common bilaterian ancestor
Erwin, D. H., & Davidson, E. H. (2002) · Development · doi:10.1242/dev.129.13.3021 · Cited by 320
Sheng, G., Thouvenot, E., Schmucker, D., Wilson, D. S., & Desplan, C. (1997) · Genes & Development · doi:10.1101/gad.11.9.1122 · Cited by 201
Regulation of mouse lens fiber cell development and differentiation by the Maf gene
Ring, B. Z., Cordes, S. P., Overbeek, P. A., & Barsh, G. S. (2000) · Development · doi:10.1242/dev.127.2.307 · Cited by 194
Role of Pax Genes in Eye Evolution
Kozmik, Z., Daube, M., Frei, E., Norman, B., Kos, L., Dishaw, L. J., Noll, M., & Piatigorsky, J. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00325-3 · Cited by 179
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Metadata
- Authors
- Cvekl, A., & Piatigorsky, J.
- Venue
- BioEssays
- Publisher
- Wiley
- Published
- 1996-08
- Volume
- 18
- Issue
- 8
- Pages
- 621-630
- ISSN
- 0265-9247 (ISSN-L)
- 1521-1878
- OpenAlex
- W1973955621
- Cited by
- 282
- References
- 1
- FWCI
- 1.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cvekl, A., & Piatigorsky, J. (1996). Lens development and crystallin gene expression: many roles for Pax‐6. BioEssays. https://doi.org/10.1002/bies.950180805
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
