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How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer

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Choice of High-Throughput Proteomics Method Affects Data Integration with Transcriptomics and the Potential Use in Biomarker Discovery

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Molecular characteristics of breast tumors in patients screened for germline predisposition from a population-based observational study

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Targeting IGF-IR improves neoadjuvant chemotherapy efficacy in breast cancers with low IGFBP7 expression

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Tearing down inequalities in the healthcare system across Europe: the BEACON project

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Enhanced cancer cell proliferation and aggressive phenotype counterbalance in breast cancer with high BRCA1 gene expression

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Tumour immune characterisation of primary triple-negative breast cancer using automated image quantification of immunohistochemistry-stained immune cells

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High Caveolin-1 mRNA expression in triple-negative breast cancer is associated with an aggressive tumor microenvironment, chemoresistance, and poor clinical outcome

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Changing Landscape of Clinical-Genomic Oncology Practice

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Tumor purity estimated from bulk DNA methylation can be used for adjusting beta values of individual samples to better reflect tumor biology

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Molecular profiling of the Basal-like intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer

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Dynamic methylation and expression of alternative promoters for oestrogen receptor alpha in cell line models of fulvestrant resistance

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A prospective cohort study identifying radiologic and tumor related factors of importance for breast conserving surgery after neoadjuvant chemotherapy

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Kataegis in clinical and molecular subgroups of primary breast cancer

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Digital PCR quantification of ultrahigh ERBB2 copy number identifies poor breast cancer survival after trastuzumab

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Cancer surgery in the genomic era

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“Association of mammographic features with molecular breast tumor profiles”

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Predicting neoadjuvant chemotherapy treatment response in hormone- receptor-positive/HER2-negative breast cancer – results from the Swedish SCAN-B population-based cohort

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Caveolin-1 gene expression provides additional prognostic information combined with PAM50 risk of recurrence (ROR) score in breast cancer

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Homologous recombination deficiency in primary ER-positive and HER2-negative breast cancer

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Automated image quantification of immunohistochemistry-stained immune cells in triple-negative breast cancerPreprint

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Capturing breast cancers’ copy-number landscape in routine pathology: Exploiting low-resolution, genome-wide sequencing to identify HRD and beyond

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Data from Prediction of Lymph Node Metastasis in Breast Cancer by Gene Expression and Clinicopathological Models: Development and Validation within a Population-Based Cohort

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Low IGFBP7 expression identifies a subset of breast cancers with favorable prognosis and sensitivity to IGF-1 receptor targeting with ganitumab: Data from I-SPY2 and SCAN-BPreprint

Godina, C., Pollak, M., & Jernström, H. (2023) · medRxiv · doi:10.1101/2023.12.18.23300129

Dynamic assessment of proliferation to guide response-adapted therapy in the setting of neoadjuvant chemotherapy in ER+/HER2- breast cancer

Saghir, H., Veerla, S., Loman, N., & Kimbung, S. (2025) · Translational Oncology · doi:10.1016/j.tranon.2025.102597

Additional file 1 of Molecular analyses of triple-negative breast cancer in the young and elderly

Aine, M., Boyacı, C., Hartman, J., Häkkinen, J., Mitra, S., Campos, A. B., Niméus, E., Ehinger, A., Vallon‐Christersson, J., Borg, Å., et al. (2021) · Figshare · doi:10.6084/m9.figshare.13889236

Additional file 4 of Molecular analyses of triple-negative breast cancer in the young and elderly

Aine, M., Boyacı, C., Hartman, J., Häkkinen, J., Mitra, S., Campos, A. B., Niméus, E., Ehinger, A., Vallon‐Christersson, J., Borg, Å., et al. (2021) · Figshare · doi:10.6084/m9.figshare.13889245

Additional file 1 of Molecular characteristics of breast tumors in patients screened for germline predisposition from a population-based observational study

Nacer, D. F., Vallon‐Christersson, J., Nordborg, N., Ehrencrona, H., Kvist, A., Borg, Å., & Staaf, J. (2023) · Figshare · doi:10.6084/m9.figshare.22637908

Additional file 3 of Molecular characteristics of breast tumors in patients screened for germline predisposition from a population-based observational study

Nacer, D. F., Vallon‐Christersson, J., Nordborg, N., Ehrencrona, H., Kvist, A., Borg, Å., & Staaf, J. (2023) · Figshare · doi:10.6084/m9.figshare.22637914

Additional file 3 of Molecular analyses of triple-negative breast cancer in the young and elderly

Aine, M., Boyacı, C., Hartman, J., Häkkinen, J., Mitra, S., Campos, A. B., Niméus, E., Ehinger, A., Vallon‐Christersson, J., Borg, Å., et al. (2021) · Figshare · doi:10.6084/m9.figshare.13889242

Additional file 6 of Molecular analyses of triple-negative breast cancer in the young and elderly

Aine, M., Boyacı, C., Hartman, J., Häkkinen, J., Mitra, S., Campos, A. B., Niméus, E., Ehinger, A., Vallon‐Christersson, J., Borg, Å., et al. (2021) · Figshare · doi:10.6084/m9.figshare.13889251

Additional file 5 of Molecular analyses of triple-negative breast cancer in the young and elderly

Aine, M., Boyacı, C., Hartman, J., Häkkinen, J., Mitra, S., Campos, A. B., Niméus, E., Ehinger, A., Vallon‐Christersson, J., Borg, Å., et al. (2021) · Figshare · doi:10.6084/m9.figshare.13889248

Additional file 7 of Molecular analyses of triple-negative breast cancer in the young and elderly

Aine, M., Boyacı, C., Hartman, J., Häkkinen, J., Mitra, S., Campos, A. B., Niméus, E., Ehinger, A., Vallon‐Christersson, J., Borg, Å., et al. (2021) · Figshare · doi:10.6084/m9.figshare.13889254

Interplay between AIB1 genotypes and radiotherapy in a Swedish population-based breast cancer cohort

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Comprehensive comparison of homologous recombination deficiency predictors in early-stage triple-negative breast cancer

Nacer, D. F., Veerla, S., Sasiain, I., Häkkinen, J., Vallon‐Christersson, J., Rossing, M., Nik‐Zainal, S., Edsjö, A., & Staaf, J. (2026) · Breast Cancer Research · doi:10.1186/s13058-026-02325-5

Integrated prediction of lung cancer histology and molecular profiles from small bronchoscopic tumor specimens

Kotevska, M., Karlsson, A., Brunnström, H., Jönsson, M., Kosieradzki, J., Barath, S., Näslund, A., Estberg, C., Arbajian, E., Rosengren, F., et al. (2026) · npj Precision Oncology · doi:10.1038/s41698-026-01623-7

Assessing the Analytical and Clinical Validity of AI-Based Tumor-Infiltrating Lymphocyte Scoring in TNBC and the Interchangeability of Machine Learning Models

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Serum Levels of Thyroid Hormones in Relation to Breast Cancer Prognosis: A Multicentre Cohort Study

Brange, A., Bengtsson, Y., Demircan, K., Vallon‐Christersson, J., Malmberg, M., Saal, L. H., Rydén, L., Borg, Å., Schomburg, L., & Manjer, J. (2026) · Cancer Medicine · doi:10.1002/cam4.72264

ESR1 mutations are associated with enhanced MTORC1 signaling in a context-dependent manner

Marchi, T. D., Kuras, M., Betancourt, L. H., Kjellström, S., Valcich, J., Vallon‐Christersson, J., Brueffer, C., Saal, L. H., Malmström, J. A., & Niméus, E. (2026) · Communications Biology · doi:10.1038/s42003-026-11096-w

The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine

Saal, L. H., Vallon-Christersson, J., Häkkinen, J., Hegardt, C., Grabau, D., Winter, C., Brueffer, C., Tang, M.-H. E., Reuterswärd, C., Schulz, R., et al. (2015) · Genome Medicine · doi:10.1186/s13073-015-0131-9 · Cited by 255 · see citing works

Population-scale integration of tumor transcriptomics into breast cancer care: a decade of the SCAN-B initiativePreprint

Saal, L. H., Dalal, H., Meng, P., Brueffer, C., Gladchuk, S., Gruvberger-Saal, S. K., Häkkinen, J., Nordborg, N., Li, M., Valcich, J., et al. (2026) · medRxiv · doi:10.64898/2026.08.20.26360879

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Abstract P1-07-17: The SCAN-B study: 5-year summary of a large-scale population-based prospective breast cancer translational genomics platform covering a wide geography of Sweden (NCT02306096)

Saal, L. H., Hegardt, C., Vallon‐Christersson, J., Häkkinen, J., Ehinger, A., Manjer, J., Larsson, C. U., Loman, N., Rydén, L., Malmberg, M., et al. (2017) · Cancer Research · doi:10.1158/1538-7445.sabcs16-p1-07-17

P3-06-08: SCAN-B: An Accelerated Translational Pipeline from Profile to Prognosis and Prediction for Individual Breast Cancer Patients.

Loman, N., Saal, L. H., Häkkinen, J., Vallon‐Christersson, J., Ringnér, M., Hegardt, C., Jönsson, G., Gruvberger-Saal, S., Kvist, A., Reuterswärd, C., et al. (2011) · Cancer Research · doi:10.1158/0008-5472.sabcs11-p3-06-08