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Cited by 375

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Randomized clinical trial of multimodal optimization and standard perioperative surgical care

Anderson, A D G, McNaught, C E, MacFie, J, Tring, I, Barker, P, Mitchell, C J·2003·British Journal of Surgery

Abstract

Background: Multimodal optimization of surgical care has been associated with reduced hospital stay and improved physical function. The aim of this randomized trial was to compare multimodal optimization with standard care in patients undergoing colonic resection. Methods: Twenty-five patients requiring elective right or left hemicolectomy were randomized to receive a ten-point optimization programme (14 patients) or conventional care (11). The groups were similar in terms of age (64 versus 68 years), male : female sex ratio (6 : 8 versus 5 : 6) and Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) score (both 26). Outcome measures were recorded before operation and on postoperative days 1, 7 and 30. They included hand grip strength, lung spirometry, and pain and fatigue scores. Further outcome measures included time to achieve a predetermined mobilization target, time to resumption of normal diet, and length of stay. Results: Optimization was associated with maintained grip strength, earlier mobilization (46 versus 69 h; P = 0·043), and significantly lower pain and fatigue scores. Patients in the optimization group tolerated a regular hospital diet significantly earlier than controls (48 versus 76 h; P < 0·001). Optimization significantly reduced the median length of hospital stay (3 versus 7 days; P = 0·002). Conclusion: Optimization of surgical care significantly improved patients' physical and psychological function in the early postoperative period and facilitated early hospital discharge.

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Metadata

Authors
Anderson, A. D. G., McNaught, C. E., MacFie, J., Tring, I., Barker, P., & Mitchell, C. J.
Venue
British Journal of Surgery
Published
2003-11-03
Volume
90
Issue
12
Pages
1497-1504
ISSN
  • 0007-1323 (ISSN-L)
  • 1365-2168
OpenAlex
W2074325074
Cited by
375
References
28
FWCI
11.60
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Randomized clinical trial of multimodal optimization and standard perioperative surgical care. https://app.cochat.ai/papers/10.1002/bjs.4371
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Anderson, A. D. G., McNaught, C. E., MacFie, J., Tring, I., Barker, P., & Mitchell, C. J. (2003). Randomized clinical trial of multimodal optimization and standard perioperative surgical care. British Journal of Surgery. https://doi.org/10.1002/bjs.4371

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.