The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Systematic review and meta-analysis of standard and extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer
Abstract
Background: Although some retrospective studies of extended radical lymphadenectomy for pancreatic cancer have suggested a survival advantage, this is controversial. Methods: A literature search identified randomized controlled trials comparing extended with standard lymphadenectomy in pancreatic cancer surgery. Overall survival was analysed using hazard ratios and standard errors. Pooled estimates of overall treatment effects were calculated using a random effects model (odds ratio and 95 per cent confidence interval). Results: Of four randomized trials identified for systematic review, three were included in a meta-analysis of survival. The log hazard ratios (standard errors) for survival for the three trials were 0·36 (0·22), − 0·15 (0·17) and − 0·21 (0·15); the weighted mean log hazard ratio for survival overall was 0·93 (95 per cent confidence interval 0·77 to 1·13), revealing no significant differences between the standard and extended procedure (P = 0·480). Morbidity and mortality rates were also comparable, with a trend towards higher rates of delayed gastric emptying for extended lymphadenectomy. The number of resected lymph nodes was significantly higher in the extended lymphadenectomy groups (P < 0·001). Conclusion: The extended procedure does not benefit overall survival, and there may even be a trend towards increased morbidity. Therefore extended lymphadenectomy should be performed only within adequately powered controlled trials, if at all.
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Cites
1 retracted
Extended versus limited lymph nodes dissection technique for adenocarcinoma of the stomach
McCulloch, P. G., Nita, M. E., Kazi, H. A., & Gama-Rodrigues, J. J. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001964.pub3 · Cited by 134
RetractedMeta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Parmar, M. K. B., Torri, V., & Stewart, L. (1998) · Statistics in Medicine · doi:10.1002/(sici)1097-0258(19981230)17:24<2815::aid-sim110>3.0.co;2-8 · Cited by 4,802
Yeo, C. J., Cameron, J. L., Lillemoe, K. D., Sohn, T. A., Campbell, K. A., Sauter, P. K., Coleman, J., Abrams, R. A., & Hruban, R. H. (2002) · Annals of Surgery · doi:10.1097/00000658-200209000-00012 · Cited by 807
Pedrazzoli, S., DiCarlo, V., Dionigi, R., Mosca, F., Pederzoli, P., Pasquali, C., Klöppel, G., Dhaene, K., & Michelassi, F. (1998) · Annals of Surgery · doi:10.1097/00000658-199810000-00007 · Cited by 692
Farnell, M. B., Pearson, R. K., Sarr, M. G., DiMagno, E. P., Burgart, L. J., Dahl, T. R., Foster, N., Sargent, D. J., & the Pancreas Cancer Working Group (2005) · Surgery · doi:10.1016/j.surg.2005.06.044 · Cited by 482
Ishikawa, O., Ohhigashi, H., Sasaki, Y., Kabuto, T., FUKUDA, I., Furukawa, H., Imaoka, S., & Iwanaga, T. (1988) · Annals of Surgery · doi:10.1097/00000658-198808000-00014 · Cited by 372
Yeo, C. J., Cameron, J. L., Sohn, T. A., Coleman, J., Sauter, P. K., Hruban, R. H., Pitt, H. A., & Lillemoe, K. D. (1999) · Annals of Surgery · doi:10.1097/00000658-199905000-00003 · Cited by 359
Knaebel, H. P., Diener, M. K., Wente, M. N., Büchler, M. W., & Seiler, C. M. (2005) · British Journal of Surgery · doi:10.1002/bjs.5000 · Cited by 335
Self-citationISHIKAWA, O., OHIGASHI, H., IMAOKA, S., FURUKAWA, H., SASAKI, Y. O., FUJITA, M., KURODA, C., & IWANAGA, T. (1992) · Annals of Surgery · doi:10.1097/00000658-199203000-00006 · Cited by 252
Kayahara, M., Nagakawa, T., Ueno, K., Ohta, T., Takeda, T., & Miyazaki, I. (1993) · Cancer · doi:10.1002/1097-0142(19931001)72:7<2118::aid-cncr2820720710>3.0.co;2-4 · Cited by 248
Riall, T. S., Cameron, J. L., Lillemoe, K. D., Campbell, K. A., Sauter, P. K., Coleman, J., Abrams, R. A., Laheru, D., Hruban, R. H., & Yeo, C. J. (2005) · Journal of Gastrointestinal Surgery · doi:10.1016/j.gassur.2005.08.034 · Cited by 219
Radical pancreatectomy for ductal cell carcinoma of the head of the pancreas
Manabe, T., Ohshio, G., Baba, N., Miyashita, T., Asano, N., Tamura, K., Yamaki, K., Nonaka, A., & Tobe, T. (1989) · Cancer · doi:10.1002/1097-0142(19890901)64:5<1132::aid-cncr2820640528>3.0.co;2-v · Cited by 203
Capussotti, L., Massucco, P., Ribero, D., Viganò, L., Muratore, A., & Calgaro, M. (2003) · Archives of Surgery · doi:10.1001/archsurg.138.12.1316 · Cited by 146
A Surgical and Pathological Based Classification of Resective Treatment of Pancreatic Cancer
Pedrazzoli, S., Beger, H. G., Obertop, H., Andrén‐Sandberg, Å., Fernández‐Cruz, L., Henne‐Bruns, D., Lüttges, J., & Neoptolemos, J. P. (1999) · Digestive Surgery · doi:10.1159/000018744 · Cited by 142
Standard vs. Radical Pancreaticoduodenectomy for Periampullary Adenocarcinoma
Nguyen, T. C., Riall, T. S., Cameron, J. L., Lillemoe, K. D., Campbell, K. A., Coleman, J., Sauter, P. K., Abrams, R. A., Hruban, R. H., & Yeo, C. J. (2003) · Journal of Gastrointestinal Surgery · doi:10.1016/s1091-255x(02)00187-7 · Cited by 127
Gastrectomy with extended lymphadenectomy for primary treatment of gastric cancer
McCulloch, P. G., Niita, M. E., Kazi, H. A., & Gama-Rodrigues, J. J. (2005) · British journal of surgery · doi:10.1002/bjs.4839 · Cited by 125
Satake, K., Nishiwaki, H., Yokomatsu, H., Kawazoe, Y., Kim, K.-S., Haku, A., Umeyama, K., & Miyazaki, I. (1992) · PubMed · Cited by 120
Henne‐Bruns, D., Vogel, I., Lüttges, J., Klöppel, G., & Kremer, B. (2000) · World Journal of Surgery · doi:10.1007/s002689910089 · Cited by 106
CONSORT and QUOROM guidelines for reporting randomized clinical trials and systematic reviews
Turpin, D. L. (2005) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2005.10.010 · Cited by 59
Imaizumi, T., Hanyu, F., Harada, N., Hatori, T., & Fukuda, A. (1998) · Digestive Surgery · doi:10.1159/000018642 · Cited by 47
Does Extended Lymphadenectomy Improve Survival of Pancreatic Cancer Patients ?
Popiela, T. J., Kędra, B., & Sierżęga, M. (2002) · Acta chirurgica Belgica · doi:10.1080/00015458.2002.11679271 · Cited by 23
Taat, C. W., van Lanschot, J. J. B., Gouma, D. J., et al. (1995) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529509090309 · Cited by 20
Reber, H. A., & Gloor, B. (1998) · Surgical Oncology Clinics of North America · doi:10.1016/s1055-3207(18)30291-6 · Cited by 18
Cited by
Kleeff, J., Korc, M., Apte, M., La Vecchia, C., Johnson, C. D., Biankin, A. V., Neale, R. E., Tempero, M., Tuveson, D. A., Hruban, R. H., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.22 · Cited by 1,982
Self-citationFitness consequences of personality: a meta-analysis
Smith, B. R., & Blumstein, D. T. (2008) · Behavioral Ecology · doi:10.1093/beheco/arm144 · Cited by 1,450
Systematic Review and Meta-Analysis of the Role of Defunctioning Stoma in Low Rectal Cancer Surgery
Hüser, N., Michalski, C. W., Erkan, M., Schuster, T., Rosenberg, R., Kleeff, J., & Friess, H. (2008) · Annals of Surgery · doi:10.1097/sla.0b013e318176bf65 · Cited by 616
Self-citationCurrent status and progress of pancreatic cancer in China
Lin, Q.-J. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i26.7988 · Cited by 285
Metadata
- Authors
- Michalski, C. W., Kleeff, J., Wente, M. N., Diener, M. K., Büchler, M. W., & Friess, H.
- Venue
- British Journal of Surgery
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-02-22
- Volume
- 94
- Issue
- 3
- Pages
- 265-273
- ISSN
- 0007-1323 (ISSN-L)
- 1365-2168
- OpenAlex
- W1964246836
- Cited by
- 302
- References
- 24
- FWCI
- 1.57
- Type
- journal article
- Language
- en
- Open access
- closed
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