The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Chitosan nanofiber biocomposites for potential wound healing applications: Antioxidant activity with synergic antibacterial effect
Open accessAbstract
Bacterial wound infection is one of the most common nosocomial infections. The unnecessary employment of antibiotics led to raising the growth of antibiotic‐resistant bacteria. Accordingly, alternative armaments capable of accelerating wound healing along with bactericidal effects are urgently needed. Considering this, we fabricated chitosan (CS)/polyethylene oxide (PEO) nanofibers armed with antibacterial silver and zinc oxide nanoparticles. The nanocomposites exhibited a high antioxidant effect and antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. Besides, based on the results of the cell viability assays, the optimum concentration of ZnONPs and AgNPs in the nanofibrous mats is 0.2% w/v and 0.08% w/v respectively and had no cytotoxicity on fibroblast cells. The scaffold also showed good blood compatibility according to the effects of coagulation time. As well as significant fibroblast migration and proliferation on the wound margin, according to wound‐healing assay. All in all, the developed biocompatible, antioxidant, and antibacterial Ag‐ZnO NPs incorporated CS/PEO nanofibrous mats showed their potential as an effective wound dressing.
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Cites
Piezoelectric Nanogenerators Based on Zinc Oxide Nanowire Arrays
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Silver nanoparticles as a new generation of antimicrobials
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Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism
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Drug delivery systems and materials for wound healing applications
Saghazadeh, S., Rinoldi, C., Schot, M., Kashaf, S. S., Sharifi, F., Jalilian, E., Nuutila, K., Giatsidis, G., Mostafalu, P., Derakhshandeh, H., et al. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.04.008 · Cited by 842
Electrospinning for tissue engineering applications
Rahmati, M., Mills, D. K., Urbanska, A. M., Saeb, M. R., Venugopal, J. R., Ramakrishna, S., & Mozafari, M. (2021) · Progress in Materials Science · doi:10.1016/j.pmatsci.2020.100721 · Cited by 816
Research Techniques Made Simple: Analysis of Collective Cell Migration Using the Wound Healing Assay
Grada, A., Otero-Vinas, M., Prieto-Castrillo, F., Obagi, Z., & Falanga, V. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.11.020 · Cited by 777
Metadata
- Authors
- Bagheri, M., Validi, M., Gholipour, A., Makvandi, P., & Sharifi, E.
- Venue
- Bioengineering & Translational Medicine
- Publisher
- Wiley
- Published
- 2021-09-16
- Volume
- 7
- Issue
- 1
- Pages
- e10254-e10254
- ISSN
- 2380-6761 (ISSN-L)
- OpenAlex
- W3198158797
- Cited by
- 268
- References
- 63
- FWCI
- 9.84
- Type
- journal article
- Language
- en
- Open access
- gold
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- Bagheri, M., Validi, M., Gholipour, A., Makvandi, P., & Sharifi, E. (2022). Chitosan nanofiber biocomposites for potential wound healing applications: Antioxidant activity with synergic antibacterial effect. Bioengineering & Translational Medicine. https://doi.org/10.1002/btm2.10254
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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