The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The Biochemistry of Drug Metabolism – An Introduction: Part 2. Redox Reactions and Their Enzymes
Abstract
This review continues a general presentation of the metabolism of drugs and other xenobiotics started in a recent issue of Chemistry & Biodiversity.This Part 2 presents the numerous oxidoreductases involved, their nomenclature, relevant biochemical properties, catalytic mechanisms, and the very diverse reactions they catalyze. Many medicinally, environmentally, and toxicologically relevant examples are presented and discussed. Cytochromes P450 occupy a majority of the pages of Part 2, but a large number of relevant oxidoreductases are also considered,e.g., flavin‐containing monooxygenases, amine oxidases, molybdenum hydroxylases, peroxidases, and the innumerable dehydrogenases/reductases.
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Cites
Role of Quinones in Toxicology
Bolton, J. L., Trush, M. A., Penning, T. M., Dryhurst, G., & Monks, T. J. (2000) · Chemical Research in Toxicology · doi:10.1021/tx9902082 · Cited by 1,703
Frezza, M., di Padova, C., Pozzato, G., Terpin, M., Baraona, E., & Lieber, C. S. (1990) · New England Journal of Medicine · doi:10.1056/nejm199001113220205 · Cited by 1,328
Duester, G. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01497.x · Cited by 570
Hanukoglu, I. (2006) · Drug Metabolism Reviews · doi:10.1080/03602530600570040 · Cited by 293
Klyosov, A. A., Rashkovetsky, L. G., Tahir, M. K., & Keung, W.-M. (1996) · Biochemistry · doi:10.1021/bi9521093 · Cited by 200
Sulfamethoxazole is metabolized to the hydroxylamine in humans
Cribb, A. E., & Spielberg, S. P. (1992) · Clinical Pharmacology and Therapeutics · doi:10.1038/clpt.1992.57 · Cited by 175
McKillop, D., Hutchison, M., Partridge, E. A., Bushby, N., Cooper, C. M. F., Clarkson-Jones, J. A., Herron, W., & Swaisland, H. C. (2004) · Xenobiotica · doi:10.1080/00498250400009171 · Cited by 130
Cited by
The Methylation Effect in Medicinal Chemistry
Barreiro, E. J., Kümmerle, A. E., & Fraga, C. A. M. (2011) · Chemical Reviews · doi:10.1021/cr200060g · Cited by 1,017
Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?
Jockers, R., Maurice, P., Boutin, J. A., & Delagrange, P. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.184 · Cited by 293
Agrawal, V., Huang, N., & Miller, W. L. (2008) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e32830054ac · Cited by 117
Metadata
- Authors
- Testa, B., & Krämer, S. D.
- Venue
- Chemistry & Biodiversity
- Publisher
- Wiley
- Published
- 2007-03
- Volume
- 4
- Issue
- 3
- Pages
- 257-405
- ISSN
- 1612-1872 (ISSN-L)
- 1612-1880
- OpenAlex
- W2952997412
- Cited by
- 171
- References
- 7
- FWCI
- 9.55
- Type
- journal article
- Language
- en
- Open access
- closed
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