The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Azide: A Unique Dipole for Metal‐Free Bioorthogonal Ligations
Abstract
Covalently bound azide on a (small) organic molecule or a (large) biomolecular structure has proven an important handle for bioconjugation. Azides are readily introduced, small, and stable, yet undergo smooth ligation with a range of reactive probes under mild conditions. In particular, the potential of azides to undergo metal‐free reactions with strained unsaturated systems has inspired the development of an increasing number of reactive probes, which are comprehensively summarized here. For each individual probe, the synthetic preparation is described, together with reaction kinetics and the full range of applications, from materials science to glycoprofiling. Finally, a qualitative and quantitative comparison of azido‐reactive probes is provided.
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Cites
Tornøe, C. W., Christensen, C., & Meldal, M. (2002) · The Journal of Organic Chemistry · doi:10.1021/jo011148j · Cited by 8,696
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
Sletten, E. M., & Bertozzi, C. R. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900942 · Cited by 3,165
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Kamaly, N., Xiao, Z., Valencia, P. M., Radovic-Moreno, A. F., & Farokhzad, O. C. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15344k · Cited by 1,730
Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation
McKay, C. S., & Finn, M. G. (2014) · Chemistry & Biology · doi:10.1016/j.chembiol.2014.09.002 · Cited by 768
Dommerholt, J., Schmidt, S., Temming, R., Hendriks, L. J. A., Rutjes, F. P. J. T., van Hest, J. C. M., Lefeber, D. J., Friedl, P., & van Delft, F. L. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.201003761 · Cited by 720
Self-citationScinto, S. L., Bilodeau, D. A., Hincapie, R., Lee, W., Nguyen, S. S., Xu, M., am Ende, C. W., Finn, M. G., Lang, K., Lin, Q., et al. (2021) · Nature Reviews Methods Primers · doi:10.1038/s43586-021-00028-z · Cited by 592
Metadata
- Authors
- Debets, M. F., van der Doelen, C. W. J., Rutjes, F. P. J. T., & van Delft, F. L.
- Venue
- ChemBioChem
- Publisher
- Wiley
- Published
- 2010-06-07
- Volume
- 11
- Issue
- 9
- Pages
- 1168-1184
- ISSN
- 1439-4227 (ISSN-L)
- 1439-7633
- OpenAlex
- W2056880409
- Cited by
- 240
- References
- 2
- FWCI
- 12.47
- Type
- journal article
- Language
- en
- Open access
- closed
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- Debets, M. F., van der Doelen, C. W. J., Rutjes, F. P. J. T., & van Delft, F. L. (2010). Azide: A Unique Dipole for Metal‐Free Bioorthogonal Ligations. ChemBioChem. https://doi.org/10.1002/cbic.201000064
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