Etiology of Syncope in Patients Hospitalized With Syncope and Predictors of Mortality and Rehospitalization for Syncope at 27‐Month Follow‐Up
Open accessAbstract
The authors investigated the etiologies of syncope and risk factors for mortality and rehospitalization for syncope at 27‐month follow‐up in 325 consecutive patients, mean age 66 years, hospitalized for syncope. The causes of syncope were diagnosed in 241 patients (74%). Of 325 patients, 13 (4%) were rehospitalized for syncope and 38 (12%) died. Stepwise logistic regression analysis showed that significant independent prognostic factors for rehospitalization for syncope were diabetes (odds ratio [OR], 5.7; 95% confidence interval [CI], 1.6–20.4), atrial fibrillation (OR, 4.0; 95% CI, 1.0–15.6), and smoking (OR, 4.6; 95% CI, 1.3–16.8). Stepwise Cox regression analysis showed that significant independent prognostic factors for time to mortality were diabetes (hazard ratio [HR], 2.7; 95% CI, 1.4–5.2), coronary artery bypass graft surgery (HR, 2.9; 95% CI, 1.3–6.5), malignancy history (HR, 2.5; 95% CI, 1.2–5.2), narcotics use (HR, 4.0; 95% CI, 1.7–9.8), smoking (HR, 2.8; 95% CI, 1.4–5.5), atrial fibrillation (HR, 2.4; 95% CI, 1.0–5.4), and volume depletion (HR, 2.8; 95% CI, 1.4–5.8). Copyright © 2011 Wiley Periodicals, Inc. The authors have no funding, financial relationships, or conflicts of interest to disclose.
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Presence of ≥1 serious medical condition is the key determinant for further in-hospital management of patients after syncope.
“Presence of ≥1 serious medical condition, summarized in Table 7, is the key determinant for further in-hospital management of patients after syncope (90,98).”
From 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (2017) · cites this paper as [98]
The Discussion says patients should be stratified to identify those needing a more extensive workup, and notes that comorbidities can complicate evaluation. It does not say that the presence of at least one serious medical condition is the key determinant of further in-hospital management. (LLM, conf=0.82)
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- Authors
- Sule, S., Palaniswamy, C., Aronow, W. S., Ahn, C., Peterson, S. J., Adapa, S., & Mudambi, L.
- Affiliations
- New York Medical College (US)
- The University of Texas Southwestern Medical Center (US)
- Corresponding author
- Aronow, Wilbert S.
- Venue
- Clinical Cardiology
- Publisher
- Wiley
- Published
- 2011-01
- Volume
- 34
- Issue
- 1
- Pages
- 35-38
- ISSN
- 0160-9289 (ISSN-L)
- 1932-8737
- PMC
- PMC6652658
- OpenAlex
- W2103977578
- Cited by
- 35
- References
- 11
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 4 · 2017: 6 · 2016: 1 · 2015: 3 · 2014: 3 · 2013: 3 · 2012: 5
- FWCI
- 3.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Cardiology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
- Keywords
- syncope, syncope etiology, mortality, hospital readmission, prognostic factors, diabetes mellitus, atrial fibrillation, smoking, coronary artery bypass grafting, history of malignancy, narcotic use, hypovolemia, hospitalized patients
- MeSH terms
- Aged, Aged, 80 and over, Female, Follow-Up Studies, Hospitalization, Humans, Male, Middle Aged, Patient Readmission, Risk Factors, Syncope, Time Factors, Logistic Models, Proportional Hazards Models, Odds Ratio, Risk Assessment
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