The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Topical Delivery of Silver Nanoparticles Promotes Wound Healing
Abstract
Wound healing is a complex process and has been the subject of intense research for a long time. The recent emergence of nanotechnology has provided a new therapeutic modality in silver nanoparticles for use in burn wounds. Nonetheless, the beneficial effects of silver nanoparticles on wound healing remain unknown. We investigated the wound‐healing properties of silver nanoparticles in an animal model and found that rapid healing and improved cosmetic appearance occur in a dose‐dependent manner. Furthermore, through quantitative PCR, immunohistochemistry, and proteomic studies, we showed that silver nanoparticles exert positive effects through their antimicrobial properties, reduction in wound inflammation, and modulation of fibrogenic cytokines. These results have given insight into the actions of silver and have provided a novel therapeutic direction for wound treatment in clinical practice.
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Brown, L. F., Yeo, K. T., Berse, B., Yeo, T. K., Senger, D. R., Dvorak, H. F., & van de Water, L. (1992) · The Journal of experimental medicine · doi:10.1084/jem.176.5.1375 · Cited by 878
Engelhardt, E., Toksoy, A., Goebeler, M., Debus, S., Bröcker, E.-B., & Gillitzer, R. (1998) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)65699-4 · Cited by 435
Cited by
Silver nanoparticles: A new view on mechanistic aspects on antimicrobial activity
Durán, N., Durán, M., de Jesus, M. B., Seabra, A. B., Fávaro, W. J., & Nakazato, G. (2016) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2015.11.016 · Cited by 1,542
Silver nanoparticles: Synthesis, medical applications and biosafety
Xu, L., Wang, Y.-Y., Huang, J., Chen, C.-Y., Wang, Z.-X., & Xie, H. (2020) · Theranostics · doi:10.7150/thno.45413 · Cited by 1,315
Ferdous, Z., & Nemmar, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072375 · Cited by 1,019
Nanoparticles and microparticles for skin drug delivery
Prow, T. W., Grice, J. E., Lin, L. L., Faye, R., Butler, M., Becker, W., Wurm, E. M. T., Yoong, C., Robertson, T. A., Soyer, H. P., et al. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.01.012 · Cited by 873
You, C., Li, Q., Wang, X., Wu, P., Ho, J. K., Jin, R., Zhang, L., Shao, H., & Han, C. (2017) · Scientific Reports · doi:10.1038/s41598-017-10481-0 · Cited by 304
Metadata
- Authors
- Tian, J., Wong, K. K. Y., Ho, C., Lok, C., Yu, W., Che, C., Chiu, J., & Tam, P. K. H.
- Venue
- ChemMedChem
- Publisher
- Wiley
- Published
- 2006-12-27
- Volume
- 2
- Issue
- 1
- Pages
- 129-136
- ISSN
- 1860-7179 (ISSN-L)
- 1860-7187
- OpenAlex
- W2100767817
- Cited by
- 983
- References
- 3
- FWCI
- 10.10
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tian, J., Wong, K. K. Y., Ho, C., Lok, C., Yu, W., Che, C., Chiu, J., & Tam, P. K. H. (2007). Topical Delivery of Silver Nanoparticles Promotes Wound Healing. ChemMedChem. https://doi.org/10.1002/cmdc.200600171
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