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Cited by 1,019

The DOI matches its Crossref record; 180 of the 180 references it cites were found in a registry or an index.

Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure

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Ferdous, Zannatul, Nemmar, Abderrahim·2020·International Journal of Molecular Sciences
DOI 10.3390/ijms21072375
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Abstract

Engineered nanomaterials (ENMs) have gained huge importance in technological advancements over the past few years. Among the various ENMs, silver nanoparticles (AgNPs) have become one of the most explored nanotechnology-derived nanostructures and have been intensively investigated for their unique physicochemical properties. The widespread commercial and biomedical application of nanosilver include its use as a catalyst and an optical receptor in cosmetics, electronics and textile engineering, as a bactericidal agent, and in wound dressings, surgical instruments, and disinfectants. This, in turn, has increased the potential for interactions of AgNPs with terrestrial and aquatic environments, as well as potential exposure and toxicity to human health. In the present review, after giving an overview of ENMs, we discuss the current advances on the physiochemical properties of AgNPs with specific emphasis on biodistribution and both in vitro and in vivo toxicity following various routes of exposure. Most in vitro studies have demonstrated the size-, dose- and coating-dependent cellular uptake of AgNPs. Following NPs exposure, in vivo biodistribution studies have reported Ag accumulation and toxicity to local as well as distant organs. Though there has been an increase in the number of studies in this area, more investigations are required to understand the mechanisms of toxicity following various modes of exposure to AgNPs.

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Metadata

Authors
Ferdous, Z., & Nemmar, A.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2020-03-30
Volume
21
Issue
7
Pages
2375
ISSN
1422-0067 (ISSN-L)
DOI
10.3390/ijms21072375
OpenAlex
W3013181597
Cited by
1,019
References
180
FWCI
50.34
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure. https://app.cochat.ai/papers/10.3390/ijms21072375
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Ferdous, Z., & Nemmar, A. (2020). Health Impact of Silver Nanoparticles: A Review of the Biodistribution and Toxicity Following Various Routes of Exposure. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21072375

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.