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Cited by 983

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Topical Delivery of Silver Nanoparticles Promotes Wound Healing

Tian, Jun, Wong, Kenneth K. Y., Ho, Chi‐Ming, Lok, Chun‐Nam, Yu, Wing‐Yiu, Che, Chi‐Ming, Chiu, Jen‐Fu, Tam, Paul K. H.·2007·ChemMedChem
DOI 10.1002/cmdc.200600171
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Abstract

Wound healing is a complex process and has been the subject of intense research for a long time. The recent emergence of nanotechnology has provided a new therapeutic modality in silver nanoparticles for use in burn wounds. Nonetheless, the beneficial effects of silver nanoparticles on wound healing remain unknown. We investigated the wound‐healing properties of silver nanoparticles in an animal model and found that rapid healing and improved cosmetic appearance occur in a dose‐dependent manner. Furthermore, through quantitative PCR, immunohistochemistry, and proteomic studies, we showed that silver nanoparticles exert positive effects through their antimicrobial properties, reduction in wound inflammation, and modulation of fibrogenic cytokines. These results have given insight into the actions of silver and have provided a novel therapeutic direction for wound treatment in clinical practice.

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Crossref · 10.1002/cmdc.200600171

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Metadata

Authors
Tian, J., Wong, K. K. Y., Ho, C., Lok, C., Yu, W., Che, C., Chiu, J., & Tam, P. K. H.
Venue
ChemMedChem
Publisher
Wiley
Published
2006-12-27
Volume
2
Issue
1
Pages
129-136
ISSN
  • 1860-7179 (ISSN-L)
  • 1860-7187
DOI
10.1002/cmdc.200600171
OpenAlex
W2100767817
Cited by
983
References
41
FWCI
10.10
Type
journal article
Language
en
Open access
closed

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.