CoChat
Sign Up
Cited by 76Neuroscience of respiration and sleepRespiratory and Cough-Related ResearchHeart Rate Variability and Autonomic Control

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Axonal projections of pulmonary slowly adapting receptor relay neurons in the rat.

Ezure, Kazuhisa, Tanaka, Ikuko, Saito, Yoshiaki, Otake, Kazuyoshi·2002·Journal of Comparative Neurology
DOI 10.1002/cne.10185
Open this paper in CoChat — free account

Abstract

We elucidated efferent projections of second‐order relay neurons (P‐cells) activated by afferents originating from slowly adapting pulmonary receptors (SARs) to determine the central pathway of the SAR‐evoked reflexes. Special attention was paid to visualizing the P‐cell projections within the nucleus tractus solitarii (NTS), which may correspond to the inhibitory pathway from P‐cells to second‐order relay neurons (RAR‐cells) of rapidly adapting pulmonary receptors. P‐cells were recorded from the NTS in Nembutal‐anesthetized, paralyzed, and artificially ventilated rats. First, we used electrophysiological methods of antidromic mapping and showed that the majority of the P‐cells examined projected their axons to the caudal NTS and to the dorsolateral pons corresponding to the parabrachial complex. Second, a mixture of HRP and Neurobiotin was injected intracellularly or juxtramembranously into P‐cells. (1) Stained P‐cells (n = 7) were located laterally to the solitary tract and had dendrites extending characteristically along the lateral border of the solitary tract. (2) All P‐cells had stem axons projecting to the ipsilateral medulla. Of these, the axons from five P‐cells projected to the nucleus ambiguus and its vicinity with distributing boutons. Some of these axons further ascended in the ventrolateral medulla, and distributed boutons in the areas ventral or ventrolateral to the nucleus ambiguus. (3) All the P‐cells had axonal branches with boutons in the NTS area. In particular, axons from three P‐cells projected bilaterally to the medial NTS caudal to the obex, i.e., to the area of RAR‐cells. These results show anatomic substrates for the connections implicated in the P‐cell inhibition of RAR‐cells as well as the SAR‐induced respiratory reflexes. J. Comp. Neurol. 446:81–94, 2002. © 2002 Wiley‐Liss, Inc.

Overview

Integrity signals

Registry

Crossref · 10.1002/cne.10185

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 4

  1. Anders K, 1987, Morphology of medullary pump‐neurones of cats, Pflugers Arch, 408, R54
  2. Duffin J, 1995, Respiratory rhythm generation: focus on the rostral ventrolateral medulla, News Physiol Sci, 10, 133
  3. Hayashi F, 1998, Axonal projection patterns of pump cells within the medulla, Jpn J Physiol, 48, S80
  4. Kubin L, 1980, Properties of the rostral NRA expiratory neurones projecting to the contralateral NTS group, Neurosci Lett, 5, S141

Cited by

Sorted by citations

See all 76

Related

See all

Metadata

Authors
Ezure, K., Tanaka, I., Saito, Y., & Otake, K.
Affiliations
Tokyo Medical and Dental University (JP)
Corresponding author
Ezure, Kazuhisa
ORCID
Saito, Yoshiaki
Venue
Journal of Comparative Neurology
Publisher
Wiley
Published
2002-03-19
Volume
446
Issue
1
Pages
81-94
ISSN
  • 0021-9967 (ISSN-L)
  • 1096-9861
DOI
10.1002/cne.10185
OpenAlex
W2086248309
Cited by
76
References
40
Citations by year
2025: 1 · 2023: 2 · 2022: 2 · 2020: 2 · 2019: 5 · 2018: 1 · 2016: 2 · 2015: 1 · 2014: 5 · 2013: 3 · 2012: 4
FWCI
1.16
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • The Journal of Comparative Neurology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory and Cough-Related Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Keywords
P cells, nucleus tractus solitarius, axonal projections, parabrachial complex, nucleus ambiguus, ventrolateral medulla, respiratory reflexes, central pathways, rats
MeSH terms
Action Potentials, Animals, Axons, Bronchi, Dendrites, Mechanoreceptors, Nerve Net, Neural Conduction, Neural Inhibition, Pons, Reaction Time, Respiratory Center, Vagus Nerve, Rats, Wistar, Solitary Nucleus, Presynaptic Terminals, Visceral Afferents, Cell Size, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review