Cited by 185Hypothalamic control of reproductive hormonesOlfactory and Sensory Function StudiesNeuroendocrine regulation and behavior

The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.

Differential projections of the anterior and posterior regions of the medial amygdaloid nucleus in the syrian hamster

Gomez, Diana M., Newman, Sarah Winans·1992·Journal of Comparative Neurology

DOI 10.1002/cne.903170208

Open this paper in CoChat — free account

Abstract

The medial nucleus of the amygdala is important for the neural control of reproductive behavior in the adult male Syrian hamster. Two types of signals are essential for this behavior, chemosensory stimuli and gonadal steroids; these signals appear to be received in different parts of the medial nucleus. The anterior region receives input from olfactory and vomeronasal systems, both of which are required for this behavior, whereas the posterior region receives gonadal hormone inputs. Behavioral studies have also suggested a functional differentiation of these two areas; electrolytic lesions of the anterior, but not the posterior, part eliminates normal sexual behavior. In this study, the efferent projections of the anterior and posterior divisions of the medial nucleus of the amygdala in the Syrian hamster were analyzed throughout the forebrain after injections of the anterograde neuronal tracer, Phaseolus vulgaris-leucoagglutinin. Neurons of the anterior, but not the posterior, medial nucleus, were found to project to numerous olfactory bulb projection areas and to the ventral striatopallidal complex. Within areas of the chemosensory circuitry that control reproductive behavior, the anterior region of the medial nucleus projects to the intermediate part of the posterior bed nucleus of the stria terminalis and the lateral part of the medial preoptic area, whereas the posterior region of the medial nucleus projects to the medial parts of these areas. Differences in targets were also observed in the ventromedial nucleus of the hypothalamus where the anterior region projects to the core while the posterior part projects to the shell of this nucleus. Furthermore, reciprocal projections between the anterior and posterior regions of the medial nucleus were observed. Taken together, these studies support the hypothesis that the anterior and posterior regions of the medial amygdaloid nucleus provide substantially different contributions to the control of reproductive behaviors.

Integrity signals

Registry

Crossref · 10.1002/cne.903170208

Cites

59 of 59 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The rat nervous system
Paxinos, G. (1985) · Cited by 3,715
Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study
Simerly, R. B., Swanson, L. W., Chang, C., & Muramatsu, M. (1990) · Journal of Comparative Neurology · doi:10.1002/cne.902940107 · Cited by 2,118
Amygdaloid projections to subcortical structures within the basal forebrain and brainstem in the rat and cat
Krettek, J. E., & Price, J. L. (1978) · Journal of Comparative Neurology · doi:10.1002/cne.901780204 · Cited by 1,293
New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata
Alheid, G. F., & Heimer, L. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90217-5 · Cited by 1,217
The connections of the septal region in the rat
Swanson, L. W., & Cowan, W. M. (1979) · The Journal of Comparative Neurology · doi:10.1002/cne.901860408 · Cited by 1,136
The differential projections of the olfactory bulb and accessory olfactory bulb in mammals
Scalia, F., & Winans, S. S. (1975) · The Journal of Comparative Neurology · doi:10.1002/cne.901610105 · Cited by 978
The amygdalostriatal projection in the rat—an anatomical study by anterograde and retrograde tracing methods
Kelley, A. E., Domesick, V. B., & Nauta, W. J. H. (1982) · Neuroscience · doi:10.1016/0306-4522(82)90067-7 · Cited by 888
Projections from the amygdaloid complex to the cerebral cortex and thalamus in the rat and cat
Krettek, J. E., & Price, J. L. (1977) · Journal of Comparative Neurology · doi:10.1002/cne.901720408 · Cited by 785
A description of the amygdaloid complex in the rat and cat with observations on intra‐amygdaloid axonal connections
Krettek, J. E., & Price, J. L. (1978) · Journal of Comparative Neurology · doi:10.1002/cne.901780205 · Cited by 727
The afferent connections of the main and the accessory olfactory bulb formations in the rat: An experimental HRP‐study
de Olmos, J. S., Hardy, H., & Heimer, L. (1978) · The Journal of Comparative Neurology · doi:10.1002/cne.901810202 · Cited by 712

Flagged first, then by citations

Show all 59 references

Research works printed but not linked: 12

Canteras N. S., 1989, The efferent connections of the amygdalo‐hippocampal area: A Phaseolus vulgaris leucoaglutinin tract‐tracing study in the rat, Soc. Neurosci., 15, 498.17
Damlama M., 1990, The efferent projections of the bed nucleus of the stria terminalis in the syrian hamster, Soc. Neurosci., 16, 103
Heimer L., 1985, The Rat Nervous System, 37
Irwin R. W., 1990, Vasopressin‐sensitive neurons in the lateral septum and bed nucleus of the stria terminals are involved in the control of flank marking behavior in golden hamsters, Soc. Neurosci., 15, 1070
Lehman M. N.(1982) Doctoral dissertation: University of Michigan. Amygdaloid efferents to the bed nucleus of the stria terminalis and the medial preoptic‐anterior hypothalamic area controlling male hamster sexual behavior:Behavioral and HRP analysis pp.110–154.
Malsbury C. W., 1987, Testosterone regulates the substance P innervation of the medial nucleus of the amygdale, Soc. Neurosci., 13, 1576
Newman S. W., 1991, Androgen and estrogen concentrating neurons in the medial preoptic area and the medial nucleus of the amygdala, Soc. Neurosci., 17, 1411
Paxinos G., 1985, The Rat Nervous System, Vol. 1, Forebrain and Midbrain
Price J. L., 1987, Handbook of Chemical Neuroanatomy, Vol. 5, Integrated Systems of the CNS, Part I, 279
Swann J. M., 1987, Effects of castration and testosterone treatment on substance P levels within the vomeronasal pathway of the male golden hamster, Soc. Neurosci., 13, 1576
Swanson L. W., 1987, Handbook of Chemical Neuroanatomy, Vol. 5, Integrated Systems of the CNS, Part I, 1
Switzer R. C., 1985, The Rat Nervous System, 1

Sorted by citations

The Medial Extended Amygdala in Male Reproductive Behavior A Node in the Mammalian Social Behavior Network
NEWMAN, S. W. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09271.x · Cited by 1,189
Organization of projections from the medial nucleus of the amygdala: A PHAL study in the rat
Canteras, N. S., Simerly, R. B., & Swanson, L. W. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903600203 · Cited by 897
Topography of projections from amygdala to bed nuclei of the stria terminalis
Dong, H.-W., Petrovich, G. D., & Swanson, L. W. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00079-0 · Cited by 714
Overshadowed by the amygdala: The bed nucleus of the stria terminalis emerges as key to psychiatric disorders
Lebow, M. A., & Chen, A. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.1 · Cited by 660
Structure and function of the vomeronasal system: an update
Halpern, M. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00103-5 · Cited by 639
“Thus, anatomical evidence from mammals and reptiles strongly supports the view that interactions between these two systems occur in the telencephalon(Gomez and Newman, 1992; Kevetter and Winans, 1981; Krettek and Price, 1978a,b; Lanuza et al., 1998; Lanuza and Halpern, 1997; Lohman and Smeets, 1993; Mart́ ınez-Garćıa…”
Background
Lhx6 delineates a pathway mediating innate reproductive behaviors from the amygdala to the hypothalamus
Choi, G. B., Dong, H.-W., Murphy, A. J., Valenzuela, D. M., Yancopoulos, G. D., Swanson, L. W., & Anderson, D. J. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.011 · Cited by 462
“Although amygdalar-hypothalamic pathways mediating reproduction and defense have been mapped extensively with anterograde tracers (Canteras et al., 1995; Coolen and Wood, 1998; Dong et al., 2001; Gomez and Newman, 1992; Kevetter and Winans, 1981), there is, so far, no clear model to suggest where and how decisions bet…”
Male Sexual Behavior
Hull, E. M., & Rodrı́guez–Manzo, G. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00001-2 · Cited by 374
Intrinsic GABAergic neurons in the rat central extended amygdala
Sun, N., & Cassell, M. D. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903300308 · Cited by 348
The structural organization of connections between hypothalamus and cerebral cortex 1Published on the World Wide Web on 2 June 1997. 1
Risold, P., Thompson, R. H., & Swanson, L. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00007-6 · Cited by 356
Extended Amygdala and Basal Forebrain
Alheid, G. F. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07082.x · Cited by 334
Mating and agonistic behavior produce different patterns of Fos immunolabeling in the male Syrian hamster brain
Kollack‐Walker, S., & Newman, S. W. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00563-k · Cited by 315
Projections from bed nuclei of the stria terminalis, posterior division: Implications for cerebral hemisphere regulation of defensive and reproductive behaviors
Dong, H., & Swanson, L. W. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20002 · Cited by 296
The Limbic System of Tetrapods: A Comparative Analysis of Cortical and Amygdalar Populations
Bruce, L. L., & Neary, T. J. (2008) · Brain Behavior and Evolution · doi:10.1159/000113276 · Cited by 292
Substantia innominata: a notion which impedes clinical–anatomical correlations in neuropsychiatric disorders
Heimer, L., Harlan, R. E., Alheid, G. F., Garcia, M. M., & de Olmos, J. S. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00405-8 · Cited by 289
Afferent projections to nucleus reuniens of the thalamus
McKenna, J. T., & Vertes, R. P. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20342 · Cited by 272
“We demonstrated moderate to dense projections from the medial nucleus of amygdala (MEA; anterior and posterior divisions) and anterior cortical nucleus to RE and relatively minor projections from the central, basal, posterior, and posterior cortical nuclei of amygdala to RE (Table 1).”
BackgroundInfluential
Neural Connections of the Anterior Hypothalamus and Agonistic Behavior in Golden Hamsters
Delville, Y., Vries, G. J. D., & Ferris, C. F. (2000) · Brain Behavior and Evolution · doi:10.1159/000006642 · Cited by 251
“Indeed, the AH is connected with the lateral parabrachial nucleus and the nucleus solitarius, areas involved in the relay of autonomic inputs to the brain [Saper and Loewy, 1980; Holets et al., 1988; Herbert et al., 1990; Halsell, 1992].”
Background
A field guide to the anterior olfactory nucleus (cortex)
Brunjes, P. C., Illig, K. R., & Meyer, E. A. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.08.005 · Cited by 224
“Dorsomedial nucleus of the hypothalamus Pars medialis and Pars ventroposterior Rat (PHA-L) [236] Medial amygdala—anterior part Pars medialis and Pars ventralis Hamster (PHA-L) [76]”
Background
Bidirectional connections of the medial amygdaloid nucleus in the Syrian hamster brain: Simultaneous anterograde and retrograde tract tracing
Coolen, L. M., & Wood, R. I. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980921)399:2 · Cited by 207
Organization of projections from the anterior hypothalamic nucleus: A Phaseolus vulgaris‐leucoagglutinin study in the rat
Risold, P., Canteras, N. S., & Swanson, L. W. (1994) · The Journal of Comparative Neurology · doi:10.1002/cne.903480102 · Cited by 198
Oxytocin receptors in the anteromedial bed nucleus of the stria terminalis promote stress-induced social avoidance in female California mice
Duque-Wilckens, N., Steinman, M. Q., Busnelli, M., Chini, B., Yokoyama, S., Pham, M., Laredo, S. A., Hao, R., Perkeybile, A. M., Minie, V. A., et al. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.08.024 · Cited by 181
“Anteromedial portions of the BNST receive inputs from the medial amygdala and posterior BNST and send direct projections to the PVN and central nucleus of the amygdala (70,71).”
Background
Convergence of olfactory and vomeronasal projections in the rat basal telencephalon
Pró-Sistiaga, P., Mohedano‐Moriano, A., Úbeda‐Bañón, I., Jiménez, M. D. M. A., Marcos, P., Artacho‐Pérula, E., Crespo, C., Insausti, R., & Martı́nez-Marcos, A. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21455 · Cited by 177
“Scale bar 500 m for A,B,D,G,J,M,P; 40 m for E,F,H,I,K,L,N,O,Q,R; 8 m for C,C . areas such as the piriform cortex as well (Canteras et al., 1992, 1995; Gomez and Newman, 1992; Coolen and Wood, 1998; Majak et al., 2004).”
Background
The main and the accessory olfactory systems interact in the control of mate recognition and sexual behavior
Keller, M., Baum, M. J., Brock, O., Brennan, P., & Bakker, J. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.01.020 · Cited by 172
“While main and accessory olfactory systems exhibit segregated pathways at the level of the first olfactory relays, the two systems converge downstream at several levels, including the cortical-medial amygdala [33,53,54,75,77,93,107].”
Differential efferent projections of the anterior, posteroventral, and posterodorsal subdivisions of the medial amygdala in mice
Pardo‐Bellver, C., Cádiz‐Moretti, B., Novejarque, A., Martínez‐Garciá, F., & Lanuza, E. (2012) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2012.00033 · Cited by 166
“Frontiers in Neuroanatomy www.frontiersin.org August 2012 | Volume 6 | Article 33 | 18 In summary, the Me not only receives direct projections from the main and AOBs (Scalia and Winans, 1975; Pro-Sistiaga et al., 2007; Kang et al., 2009, 2011; Cadiz-Moretti et al., in press), but also shows strong connections with bot…”
BackgroundMethodResultInfluential
Sex comparison of neuronal fos immunoreactivity in the rat vomeronasal projection circuit after chemosensory stimulation
Bressler, S., & Baum, M. J. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00493-9 · Cited by 157
Neurobiology of Male Sexual Behavior
Hull, E. M., Wood, R. W., & MCKENNA, K. (2006) · Elsevier eBooks · doi:10.1016/b978-012515400-0/50038-5 · Cited by 147
Chemosignals, hormones and mammalian reproduction
Petrulis, A. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.03.011 · Cited by 142
“…(MA, BNST, diencephalic areas), the steroid-sensitive and chemosensory sub-regions are also interconnected with one another (Coolen and Wood, 1998; Gomez and Newman, 1992) thereby providing a substrate whereby steroid hormones and chemosensory systems can interact (Been and Petrulis, 2011; Maras…”
Defective neurite extension is caused by a mutation in amyloid ?/A4 (A?) protein precursor found in Familial Alzheimer's Disease
Li, H. L., Roch, J., Sundsmo, M. P., Otero, D. A. C., Sisodia, S. S., Thomas, R. G., & Saitoh, T. (1997) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(199705)32:5 · Cited by 58
Regulation of masculine sexual behavior: involvement of brain opioids and dopamine.
van Furth, W. V., Wolterink, G., & van Ree, J. M. (1995) · Brain research. Brain research reviews · doi:10.1016/0165-0173(96)82985-7 · Cited by 144
Mating activates androgen receptor-containing neurons in chemosensory pathways of the male Syrian hamster brain
Wood, R. I., & Newman, S. W. (1993) · Brain Research · doi:10.1016/0006-8993(93)91019-o · Cited by 135
Anatomical interrelationships of the medial preoptic area and other brain regions activated following male sexual behavior: A combined Fos and tract-tracing study
Coolen, L. M., Peters, H. J. P. W., & Veening, J. G. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980803)397:3 · Cited by 136
Projections of the suprachiasmatic nuclei, subparaventricular zone and retrochiasmatic area in the golden hamster
Morin, L. P., Goodless-Sanchez, N., Smale, L., & Moore, R. Y. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90240-2 · Cited by 133
The pallial amygdala of amniote vertebrates: evolution of the concept, evolution of the structure
Martínez‐Garciá, F., Martı́nez-Marcos, A., & Lanuza, E. (2002) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00665-7 · Cited by 129
The effect of kindling of different nuclei in the left and right amygdala on anxiety in the rat
Adamec, R. E., & Morgan, H. D. (1994) · Physiology & Behavior · doi:10.1016/0031-9384(94)90002-7 · Cited by 124
The human basal forebrain. Part II
Heimer, L., de Olmos, J. S., Alheid, G. F., Pearson, J., Sakamoto, N., Shinoda, K., Marksteiner, J., & Switzer, R. C. (1999) · Handbook of Chemical Neuroanatomy · doi:10.1016/s0924-8196(99)80024-4 · Cited by 125
On the organization of olfactory and vomeronasal cortices
Martı́nez-Marcos, A. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.09.010 · Cited by 126
“…projects to different hypothalamic structures including the ventromedial hypothalamic and ventral premammillary nuclei (Kevetter and Winans, 1981a; Gomez and Newman, 1992; Canteras et al., 1995; Coolen and Wood, 1998), whereas the posteromedial cortical amygdala mainly projects to other…”
Background
Integration of chemosensory and hormonal cues is essential for mating in the male Syrian hamster
Wood, R., & Newman, S. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-11-07261.1995 · Cited by 122
“, 1993; Wood and Newman, 1993a) and the underlying neuronal connections (Gomez and Newman, 1992), suggest that chemosensory and hormonal signals are transmitted through largely separate, but parallel subdivisions within each of three brain regions: the medial amygdaloid nucleus (Me), bed nucleus of the stria terminali…”
BackgroundInfluential
Chapter 28 Theories of basal forebrain organization and the “emotional motor system”
Alheid, G. F., & Heimer, L. (1996) · Progress in brain research · doi:10.1016/s0079-6123(08)61882-8 · Cited by 115
Segregated pathways to the vomeronasal amygdala: differential projections from the anterior and posterior divisions of the accessory olfactory bulb
Mohedano‐Moriano, A., Pro‐Sistiaga, P., Úbeda‐Bañón, I., Crespo, C., Insausti, R., & Martinez‐Marcos, A. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05472.x · Cited by 114
Importance of the medial amygdala in rat penile erection evoked by remote stimuli from estrous females
Kondo, Y., Sachs, B. D., & Sakuma, Y. (1997) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)02287-0 · Cited by 113
The common organization of the amygdaloid complex in tetrapods: New concepts based on developmental, hodological and neurochemical data in anuran amphibians
Moreno, N., & González, A. (2006) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.12.005 · Cited by 111
Afferent connections of the interstitial nucleus of the posterior limb of the anterior commissure and adjacent amygdalostriatal transition area in the rat
Shammah‐Lagnado, S. J., Alheid, G. F., & Heimer, L. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)90280-4 · Cited by 106
Integration of chemosensory and hormonal cues is essential for sexual behaviour in the male syrian hamster: role of the medial amygdaloid nucleus
Wood, R. I., & Coolen, L. M. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00629-x · Cited by 102
Male Sexual Behavior
Hull, E. M., Meisel, R. L., & Sachs, B. D. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50003-2 · Cited by 104
Androgen and estrogen concentrating neurons in chemosensory pathways of the male Syrian hamster brain
Wood, R. I., Brabec, R. K., Swann, J. M., & Newman, S. W. (1992) · Brain Research · doi:10.1016/0006-8993(92)91536-n · Cited by 99
Hodological characterization of the medial amygdala in anuran amphibians
Moreno, N., & González, A. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10887 · Cited by 95
“In rodents, the MeA appears to be composed of two main divisions, the anterior and posterior divisions in hamsters (Gomez and Newman, 1992; Coolen and Wood, 1998) or the ventral (anteroventral, posteroventral, and anterodorsal) and dorsal divisions (posterodorsal) in rats (Canteras et al., 1995;…”
Background
Thinking about Networks in the Control of Male Hamster Sexual Behavior
Wood, R. I. (1997) · Hormones and Behavior · doi:10.1006/hbeh.1997.1403 · Cited by 93
“Thus, we may postu- which traverse MeA and MeP (Gomez and Newman, 1992; Canteras et al., 1995) and presumably extend be-late that the recurrent connections from MPOA to Me and BNST may increase in number or activity with sex- tween subnuclei of BNST and MPOA.”
Influential
Testosterone and its metabolites - modulators of brain functions
Durdiaková, J., Ostatníková, D., & Celec, P. (2011) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2011-1863 · Cited by 93
Testosterone Augments Neuronal Fos Responses to Estrous Odors throughout the Vomeronasal Projection Pathway of Gonadectomized Male and Female Rats
Paredes, R. G., Lopez, M., & Baum, M. J. (1998) · Hormones and Behavior · doi:10.1006/hbeh.1998.1435 · Cited by 90
“It appears that estradiol, formed in the brain from circulating testosterone, acts neonatally in the male rat to defeminize central segments of the vomeronasal projection pathway, along with its inputs to the Acb (Gomez and Newman, 1992).”
Background
Potentiation of Divergent Medial Amygdala Pathways Drives Experience-Dependent Aggression Escalation
Nordman, J. C., Ma, X., Gu, Q., Potegal, M., Li, H., Kravitz, A. V., & Li, Z. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0370-20.2020 · Cited by 93
“…pathways mediate the effect of HFPS on aggression MeApv neurons project to several regions implicated in aggression, including the VmH, BNST, MPO, and LS (Gomez and Newman, 1992; Canteras et al., 1995; Coolen and Wood, 1998; Haller et al., 2006; Nelson and Trainor, 2007; Hashikawa et al., 2016).”
Background
Estradiol, but not dihydrotestosterone, in the medial amygdala facilitates male hamster sex behavior
Wood, R. I. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(95)02204-x · Cited by 89
Afferent projections to the different medial amygdala subdivisions: a retrograde tracing study in the mouse
Cádiz‐Moretti, B., Otero‐García, M., Martínez‐Garciá, F., & Lanuza, E. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0954-y · Cited by 93
“The efferent projections of the Me have been previously characterized in several rodent species including hamsters (Gomez and Newman 1992; Coolen and Wood 1998; Maras and Petrulis 2010a), rats (Canteras et al. 1995) and mice (Usunoff et al. 2009; Pardo-Bellver et al. 2012).”
Background
Functional imaging of cortical feedback projections to the olfactory bulb
Rothermel, M., & Wachowiak, M. (2014) · Frontiers in Neural Circuits · doi:10.3389/fncir.2014.00073 · Cited by 87
“…areas including anterior piriform cortex (Haberly and Price, 1978; Luskin and Price, 1983; Haberly, 2001) and amygdala (De Carlos et al., 1989; Gomez and Newman, 1992; Canteras et al., 1995; Petrovich et al., 1996) as well as higherorder centers such as basal forebrain (Broadwell and…”
Background
Lesions centered on the medial amygdala impair scent-marking and sex-odor recognition but spare discrimination of individual odors in female golden hamsters.
Petrulis, A., & Johnston, R. E. (1999) · Behavioral Neuroscience · doi:10.1037//0735-7044.113.2.345 · Cited by 84
Evolution of the Amygdala in Vertebrates
Martínez‐Garciá, F., Novejarque, A., & Lanuza, E. (2007) · Elsevier eBooks · doi:10.1016/b0-12-370878-8/00139-7 · Cited by 80
Cortical and medial amygdala are both involved in the formation of olfactory offspring memory in sheep
Keller, M., Perrin, G., Meurisse, M., Ferreira, G., & Lévy, F. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03812.x · Cited by 79
Neuronal Fos activation in olfactory bulb and forebrain of male rats having erections in the presence of inaccessible estrous females.
Kelliher, K. R., Liu, Y.-C. A., Baum, M. J., & Sachs, B. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00050-0 · Cited by 76
Chemosignals and hormones in the neural control of mammalian sexual behavior
Petrulis, A. (2013) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2013.07.007 · Cited by 75
“Each of these regions is heavily interconnected with itself but, within each anatomical element (MA, BNST, diencephalic areas), the steroid-sensitive and chemosensory sub-regions are also interconnected with one another (Coolen and Wood, 1998; Gomez and Newman, 1992) thereby providing a substrate whereby steroid hormo…”
Effect of prenatal androgen receptor antagonist or aromatase inhibitor on sexual behavior, partner preference and neuronal Fos responses to estrous female odors in the rat accessory olfactory system
Domı́nguez-Salazar, E. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00674-6 · Cited by 74
“Many, though not all, socially relevant olfactory cues are detected and processed in rodent species by a polysynaptic accessory olfactory system (AOS) [11,12].”
Background
Effects of Vomeronasal Organ Removal on Individual Odor Discrimination, Sex-Odor Preference, and Scent Marking by Female Hamsters
Petrulis, A., Peng, M., & Johnston, R. E. (1999) · Physiology & Behavior · doi:10.1016/s0031-9384(98)00259-5 · Cited by 74
Fos-Immunoreactivity within the Extended Amygdala Is Correlated with the Onset of Sexual Satiety
Parfitt, D. B., & Newman, S. W. (1998) · Hormones and Behavior · doi:10.1006/hbeh.1998.1459 · Cited by 72
Neural mechanisms of individual and sexual recognition in Syrian hamsters (Mesocricetus auratus)
Petrulis, A. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.10.027 · Cited by 69
“Nevertheless, within each anatomical element (ME, BNST, diencephalic areas), the steroid-sensitive and chemosensory sub-regions are interconnected with one another [11,22].”
Background
Experience facilitates vomeronasal and olfactory influence on Fos expression in medial preoptic area during pheromone exposure or mating in male hamsters
Fewell, G. D., & Meredith, M. J. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02613-6 · Cited by 68
Attack priming in female Syrian golden hamsters is associated with a c-fos-coupled process within the corticomedial amygdala
Potegal, M., Ferris, C. F., Hebert, M. A., Meyerhoff, J. L., & Skaredoff, L. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00236-9 · Cited by 69
Amygdala kindling, anxiety, and corticotrophin releasing factor (CRF)
Adamec, R. E., & McKay, D. W. (1993) · Physiology & Behavior · doi:10.1016/0031-9384(93)90230-d · Cited by 68
Pubertal and seasonal plasticity in the amygdala
Romeo, R. D., & Sisk, C. L. (2001) · Brain Research · doi:10.1016/s0006-8993(00)03111-5 · Cited by 67
Cell-body lesions of the posterodorsal preoptic nucleus or posterodorsal medial amygdala, but not the parvicellular subparafascicular thalamus, disrupt mating in male gerbils
Heeb, M. M., & Yahr, P. (2000) · Physiology & Behavior · doi:10.1016/s0031-9384(99)00182-1 · Cited by 65
Anatomical and functional connections among cell groups in the gerbil brain that are activated with ejaculation
Heeb, M. M., & Yahr, P. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1346 · Cited by 62
“In studies tracing projections from the posterior medial amygdala of hamsters (Gomez and Newman, 1992) or MeApd of rats (Canteras et al., 1995), the density of fiber labeling seen just rostral and caudal to where the PdPN is found (Maragos et al., 1989; Swanson, 1992) suggests that the MeApd may…”
Background
Male rats with the testicular feminization mutation of the androgen receptor display elevated anxiety-related behavior and corticosterone response to mild stress
Zuloaga, D., Poort, J. E., Jordan, C. L., & Breedlove, S. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.07.008 · Cited by 56
“However, the MePD projects to two other hormone and stress responsive regions (BNST, MPOA) and through these projections may regulate anxiety-related behaviors (Coolen and Wood, 1998; Gomez and Newman, 1992).”
Oestrogen Receptor‐α‐Immunoreactive Neurones Project to the Suprachiasmatic Nucleus of the Female Syrian Hamster
Iglesia, D. L., Blaustein, & Bittman (1999) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1999.00341.x · Cited by 64
Pheromones, Odors, and Vasanas
McClintock, M. K. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50017-2 · Cited by 63
Sexually Dimorphic Processing of Somatosensory and Chemosensory Inputs to Forebrain Luteinizing Hormone-Releasing Hormone Neurons in Mated Ferrets
Wersinger, S. R., & Baum, M. J. (1997) · Endocrinology · doi:10.1210/en.138.3.1121 · Cited by 62
The bed nucleus of the stria terminalis in the Syrian hamster: Subnuclei and connections of the posterior division
Wood, R. I., & Swann, J. M. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.05.029 · Cited by 60
Ependymal/subependymal zone cells of postnatal and adult songbird brain generate both neurons and nonneuronal siblingsin vitro andin vivo
Goldman, S. A., Zukhar, A., Barami, K., Mikawa, T., & Niedzwiecki, D. (1996) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(199608)30:4 · Cited by 59
Amygdaloid lesion-induced obesity: relation to sexual behavior, olfaction, and the ventromedial hypothalamus.
King, B. M. (2006) · American Journal of Physiology. Regulatory Integrative and Comparative Physiology · doi:10.1152/ajpregu.00199.2006 · Cited by 59
“In fact, one of the major efferent projections from the medial amygdaloid nucleus is to the VMH via the stria terminalis (21, 38, 71, 125), and there are reciprocal connections from the VMH (20, 60, 94, 166).”
Background
Monoaminergic innervation of the macaque extended amygdala
Freedman, L. J., & Shi, C. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00157-9 · Cited by 58
Fear and power-dominance drive motivation: neural representations and pathways mediating sensory and mnemonic inputs, and outputs to premotor structures
Sewards, T. V., & Sewards, M. A. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00020-9 · Cited by 57
Differential projections from the anterior and posterior divisions of the accessory olfactory bulb to the medial amygdala in the opossum, Monodelphis domestica
Martı́nez-Marcos, A., & Halpern, M. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00797.x · Cited by 57
Obesity-inducing amygdala lesions: examination of anterograde degeneration and retrograde transport
King, B. M., Cook, J. T., Rossiter, K. N., & Rollins, B. L. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00249.2002 · Cited by 56
“Although the central extended amygdala does not seem to be innervated by the MePD (12, 36) or by the BSTIA (present results), all its components (including the central amygdaloid nucleus, its sublenticular and supracapsular extension, the interstitial nucleus of the posterior limb of the anterior commissure, and the l…”
Influential
Brief, high-frequency stimulation of the corticomedial amygdala induces a delayed and prolonged increase of aggressiveness in male Syrian golden hamsters.
Potegal, M., Hebert, M. A., DeCoster, M. A., & Meyerhoff, J. L. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.2.401 · Cited by 55
The main olfactory system mediates pheromone-induced fos expression in the extended amygdala and preoptic area of the male Syrian hamster
Swann, J. M., Rahaman, F. N., Bijak, T., & Fiber, J. M. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00227-5 · Cited by 54
Amygdalostriatal projections in the neurocircuitry for motivation: a neuroanatomical thread through the career of Ann Kelley
Zorrilla, E. P., & Koob, G. F. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.11.019 · Cited by 59
“In hamsters, Gomez and Newman (1992) used PHA-L anterograde tracing to identify a dense projection from the rostral MeA to NAc shell, fundus striati, and olfactory tubercle, findings replicated by Coolen and Wood (1998) who showed a sparser ventral striatal connection from the caudal posterdorsal…”
Method
Efferent Projections of the Anterior and Posterodorsal Regions of the Medial Nucleus of the Amygdala in the Mouse
Usunoff, K. G., Schmitt, O., Itzev, D. E., Haas, S. J.-P., Lazarov, N., Rolfs, A., & Wree, A. (2009) · Cells Tissues Organs · doi:10.1159/000209233 · Cited by 52
Chemosensory and hormone information are relayed directly between the medial amygdala, posterior bed nucleus of the stria terminalis, and medial preoptic area in male Syrian hamsters
Been, L. E., & Petrulis, A. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.02.005 · Cited by 47
“As such, main and accessory olfactory information that converges on Me can terminate at BNST or continue directly to MPOA (Coolen and Wood, 1998; Gomez and Newman, 1992), whereas accessory olfactory information received by BNST can be relayed to MPOA (Gomez and Newman, 1992; Wood and Swann, 2005).”
Background
Organization of the ophidian amygdala: Chemosensory pathways to the hypothalamus
Martínez-Marcos, A., Lanuza, E., & Halpern, M. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990913)412:1 · Cited by 45
The anterior medial amygdala transmits sexual odor information to the posterior medial amygdala and related forebrain nuclei
Maras, P. M., & Petrulis, A. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07289.x · Cited by 44
The effect of seizures and kindling on reproductive hormones in the rat
Edwards, H. E., MacLusky, N. J., & Burnham, W. M. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00034-8 · Cited by 42
Testicular hormones modulate circadian rhythms of the diurnal rodent, Octodon degus
Jechura, T. J., Walsh, J. M., & Lee, T. M. (2000) · Hormones and Behavior · doi:10.1006/hbeh.2000.1624 · Cited by 40
“In rats and hamsters, both the amygdala and PVT are sensitive to steroid hormones and both have connections to the SCN; the PVT has a direct and reciprocal connection with the SCN, while the amygdala has indirect connectivity to the SCN and a direct reciprocal projection to the PVT ( Gomez and Newman, 1992; Moga et al…”
Background
Chemosensory Function of the Amygdala
Gutiérrez‐Castellanos, N., Martı́nez-Marcos, A., Martínez‐Garciá, F., & Lanuza, E. (2010) · Vitamins and hormones · doi:10.1016/s0083-6729(10)83007-9 · Cited by 40
“Concerning the MxCA with vomeronasal predominance, the Me is a very complex nucleus usually divided, as explained above, into anterior and posterior divisions (Gomez and Newman, 1992; Usunoff et al., 2009), often further subdivided in dorsal and ventral subnuclei (Canteras et al.”
Background
Hyperinsulinemia in rats with obesity-inducing amygdaloid lesions
King, B. M., Cook, J. T., & Dallman, M. F. (1996) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1996.271.5.r1156 · Cited by 40
Amygdala
de Olmos, J. S. (2004) · Elsevier eBooks · doi:10.1016/b978-012547626-3/50023-5 · Cited by 40
Development of the vomeronasal amygdala in anuran amphibians: Hodological, neurochemical, and gene expression characterization
Moreno, N., & González, A. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21422 · Cited by 38
“…the MOB and is especially related to the ventromedial nucleus of the hypothalamus, thus modulating reproductive and defensive behaviors (Scalia and Winans, 1975; Lehman and Winans, 1982; Gomez and Newman, 1992; Canteras et al., 1995; Risold et al., 1997; Coolen and Wood, 1998; Choi et al., 2005).”
Background
Differential patterns of c-fos mRNA expression in amygdala during successive stages of odor discrimination learning.Preprint
Hess, U., Gall, C. M., Granger, R., & Lynch, G. (1997) · Learning & Memory · doi:10.1101/lm.4.3.262 · Cited by 39
Collateral projection from the amygdalo–hippocampal transition area and CA1 to the hypothalamus and medial prefrontal cortex in the rat
Chiba, T. (2000) · Neuroscience Research · doi:10.1016/s0168-0102(00)00183-8 · Cited by 37
Pheromone Sensing in Mammals: A Review of the Vomeronasal System
Torres, M. V., Ortiz‐Leal, I., & Sánchez‐Quinteiro, P. (2023) · Anatomia · doi:10.3390/anatomia2040031 · Cited by 37
Traumatic Stress Induces Prolonged Aggression Increase through Synaptic Potentiation in the Medial Amygdala Circuits
Nordman, J. C., Ma, X., & Li, Z. (2020) · eNeuro · doi:10.1523/eneuro.0147-20.2020 · Cited by 38
“…regions that influence aggressive behavior including the ventromedial hypothalamus (VmH), bed nucleus of the stria terminalis (BNST), and lateral septum (LS; Gomez and Newman, 1992; Canteras et al., 1995; Coolen and Wood, 1998; Haller et al., 2006; Nelson and Trainor, 2007; Hashikawa et al., 2016).”
Background
Lesions that functionally disconnect the anterior and posterodorsal sub-regions of the medial amygdala eliminate opposite-sex odor preference in male Syrian hamsters (Mesocricetus auratus)
Maras, P. M., & Petrulis, A. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.11.024 · Cited by 35
“Critically, substantial reciprocal fibers connect MeA and MePD (Gomez and Newman, 1992; Coolen and Wood, 1998), providing a substrate for the neural integration of these cues.”
BackgroundMethodInfluential
A Population of Kisspeptin/Neurokinin B Neurons in the Arcuate Nucleus May Be the Central Target of the Male Effect Phenomenon in Goats
Sakamoto, K., Wakabayashi, Y., Yamamura, T., TANAKA, T., Takeuchi, Y., Mori, Y., & Okamura, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081017 · Cited by 36
“The pathway and distribution of the efferent fibers of the MeA observed in goats are comparable to those demonstrated in rats [58,59] and hamsters [60], suggesting that these neural pathways are highly conserved among mammals.”
Background
Projection patterns from the amygdaloid nuclear complex to subdivisions of the dorsal raphe nucleus in the rat
Lee, H. S., Eum, Y. J., Jo, S. M., & Waterhouse, B. D. (2007) · Brain Research · doi:10.1016/j.brainres.2007.01.081 · Cited by 35
“The medial amygdaloid nucleus receives input from olfactory and vomeronasal systems as well as gonadal hormone inputs (Gomez and Newman, 1992).”
Background
Effects of Angiotensin II Microinjected into Medial Amygdala on Male Sexual Behavior in Rats
Breigeiron, M. K., Morris, M. J., Lucion, A. B., & Sanvitto, G. L. (2002) · Hormones and Behavior · doi:10.1006/hbeh.2002.1771 · Cited by 35
Differential centrifuagal afferents to the anterior and posterior accessory olfactory bulb
Martı́nez-Marcos, A., & Halpern, M. (1999) · Neuroreport · doi:10.1097/00001756-199907130-00004 · Cited by 35

Authors: Gomez, D. M., & Newman, S. W.
Affiliations: University of Michigan (US)
Venue: Journal of Comparative Neurology
Publisher: Wiley
Published: 1992-03-08
Volume: 317
Issue: 2
Pages: 195-218
ISSN: 0021-9967 (ISSN-L)
1096-9861
DOI: 10.1002/cne.903170208
OpenAlex: W2094469610
Cited by: 185
References: 59
Citations by year: 2025: 1 · 2024: 2 · 2023: 3 · 2022: 4 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 5 · 2015: 1 · 2014: 6 · 2013: 7 · 2012: 5
FWCI: 7.56
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 4598 d)
Locations: The Journal of Comparative Neurology (publishedVersion)
PubMed (publishedVersion)
Deep Blue (University of Michigan) (submittedVersion)
Funders: National Institutes of Health (2r01ns020629-05)
National Institute of Neurological Disorders and Stroke (NS-20629)
Topics: Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Keywords: medial amygdala, efferent projections, golden hamster, male reproductive behavior, olfactory bulb, vomeronasal system, bed nucleus of the stria terminalis, medial preoptic area, ventromedial hypothalamus, reciprocal projections
MeSH terms: Amygdala, Animals, Brain Mapping, Corpus Striatum, Efferent Pathways, Globus Pallidus, Cricetinae, Hypothalamus, Male, Mesocricetus, Olfactory Pathways, Preoptic Area, Sexual Behavior, Animal, Thalamus

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Differential projections of the anterior and posterior regions of the medial amygdaloid nucleus in the syrian hamster

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks