Meaning-making as a mediator of anxiety and depression reduction during cognitive behavioral therapy intervention in participants with adjustment disorders
Open accessAbstract
There is a consensus among researchers about the link between low meaning in life and anxiety and depressive symptoms. One unanswered question is whether meaning-making is a mediator of the change in anxiety and depression symptoms in participants with adjustment disorders during cognitive behavioural therapy (CBT) treatment. The aims of this study were (a) to analyse whether there was meaning-making during the application of the CBT, (b) to analyse whether meaning-making was a mediator of anxiety psychopathology and (c) to analyse whether meaning-making was a mediator of depressive symptoms. The sample was composed of 115 patients who satisfied the full Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 criteria for adjustment disorder as their primary diagnosis and completed CBT treatment in a primary care mental health service: 74.78% women, n = 86, and 25.22% men, n = 29, with a mean age of 41.89 (standard deviation [SD] = 10.39) years. The diagnosis was established using the Structured Clinical Interview for DSM-5 (SCID-5), and participants filled out the Beck Anxiety Inventory, the Beck Depression Inventory and Purpose in Life questionnaires. The therapists were clinical psychologists with experience in clinical assessment. A repeated-measures analysis of variance (ANOVA) and two mediation analyses using the bootstrap method were performed. The results indicated that (a) There was meaning-making during the CBT because the treated sample showed a statistically significant improvement in meaning in life, and (b) meaning-making during the CBT was a partial mediator between anxiety symptoms and depressive symptoms before and after the treatment. The present study suggests that meaning in life could be an important variable in the psychopathology of adjustment disorders.
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Studies in clinical and non-clinical samples of patients without a cancer diagnosis have shown that meaning in life is negatively associated with hopelessness, anxiety, emotional dysregulation, coping capacity, and depression, and is a buffer against psychopathology.
“Studies in clinical and non-clinical samples of patients without a cancer diagnosis have shown that meaning in life is an emotional state that is negatively associated with hopelessness, anxiety, emotional dysregulation, coping capacity, and depression, and it is a buffer against psychopathology (5, 6).”
From Spanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial (2022) · cites this paper as [6]
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- Authors
- Marco, J. H., Alonso, S., & Baños, R.
- Affiliations
- Universitat de València (ES)
- Valencia Catholic University Saint Vincent Martyr (ES)
- Corresponding author
- Marco, José H.
- Venue
- Clinical Psychology & Psychotherapy
- Publisher
- Wiley
- Published
- 2020-09-10
- Volume
- 28
- Issue
- 2
- Pages
- 325-333
- ISSN
- 1063-3995 (ISSN-L)
- 1099-0879
- OpenAlex
- W3083126953
- Cited by
- 31
- References
- 56
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 10 · 2021: 3
- FWCI
- 4.11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Psychology & Psychotherapy (publishedVersion)
- PubMed (publishedVersion)
- Repository of Digital Objects for Teaching Research and Culture (University of Valencia) (submittedVersion, cc-by-nc)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
- Keywords
- meaning-making, meaning in life, adjustment disorder, cognitive behavioral therapy, anxiety symptoms, depressive symptoms, mediation, primary care mental health, meaning of life
- MeSH terms
- Adjustment Disorders, Adult, Anxiety, Depression, Female, Humans, Male, Cognitive Behavioral Therapy
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