Cited by 37Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on BehaviorDecision-Making and Behavioral Economics

Reinforcer pathology: the behavioral economics of abuse liability testing

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Bickel, WK, Snider, SE, Quisenberry, AJ, Stein, JS·2017·Clinical Pharmacology & Therapeutics

Abstract

Understanding the abuse liability of novel drugs is critical to understanding the risk these new compounds pose to society. Behavioral economics, the integration of psychology and economics, can be used to predict abuse liability of novel substances. Here, we describe the behavioral economic concept of reinforcer pathology and how it may predict the use of novel drugs in existing drug‐users and initiation of use in the drug‐naive.

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  • The concept of reinforcer pathology is a recent development in the field of the behavioral economics of addiction specifically focused on how the window of time over which reinforcers are integrated can determine the relative valuation of alcohol and drugs versus other prosocial reinforcers, such as relationships and employment.

    “The concept of reinforcer pathology is a recent development in the field of the behavioral economics of addiction specifically focused on how the window of time over which reinforcers are integrated can determine the relative valuation of alcohol and drugs versus other prosocial reinforcers, such as relationships and employment [22–24].”

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Authors
Bickel, W., Snider, S., Quisenberry, A., & Stein, J.
Affiliations
  • Addiction Recovery Research Center, Virginia Tech Carilion Research Institute Roanoke Virginia USA
  • Carilion Clinic (US)
Venue
Clinical Pharmacology & Therapeutics
Publisher
Wiley
Published
2016-09-19
Volume
101
Issue
2
Pages
185-187
ISSN
  • 0009-9236 (ISSN-L)
  • 1532-6535
OpenAlex
W2476637292
Cited by
37
References
5
Citations by year
2026: 4 · 2024: 3 · 2023: 2 · 2022: 2 · 2021: 4 · 2020: 4 · 2019: 9 · 2018: 6 · 2017: 3
FWCI
5.62
Type
journal article
Language
en
Open access
Locations
  • Clinical Pharmacology & Therapeutics (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute on Drug Abuse (R01DA042535, R01DA034755)
  • National Cancer Institute (U19CA157345, P01CA200512)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
Keywords
abuse liability, behavioral economics, novel drugs, drug initiation, drug use prediction, substance abuse risk
MeSH terms
Alcohol Drinking, Alcoholic Intoxication, Humans, Substance-Related Disorders, Economics, Behavioral

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