When and how can real world data analyses substitute for randomized controlled trials?

Cited by (316)

Items 201–300 of 316

1. Using Healthcare Databases to Replicate Trial Findings for Supplemental Indications: Adalimumab in Patients with Ulcerative Colitis
   Julia Spoendlin, Rishi J. Desai, Jessica Myers Franklin, Robert J. Glynn, Emma Payne, Sebastian Schneeweiß · 2020 · Clinical Pharmacology & Therapeutics
2. Validation of diagnoses of liver disorders in users of systemic azole antifungal medication in Sweden
   Diego Hernan Giunta, Pär Karlsson, Muhammad Younus, Ina Anveden Berglind, Helle Kieler, Johan Reutfors · 2024 · BMC Gastroenterology
3. Considerations for master protocols using external controls
   Jie Chen, Xiaoyun Li, Chengxing Cindy Lu, Sammy Yuan, Godwin Yung, Jingjing Ye, Hong Tian, Jianchang Lin · 2024 · Journal of Biopharmaceutical Statistics
4. Facilitated Subcutaneous Immunoglobulin Treatment Patterns in Pediatric Patients with Primary Immunodeficiency Diseases
   Monika Mach-Tomalska, Anna Pituch‐Noworolska, Ewa Bień, Magdalena Malanowska, Edyta Machura, Anna Pukas-Bochenek, Ewelina Chrobak, Małgorzata Pac, Barbara Maria Pietrucha, Szymon Drygała et al. · 2024 · Immunotherapy
5. Exploring the Intersection of Machine Learning and Causality in Advanced Diabetes Management: New Insight and Opportunities
   Sahar Echajei, Yman Chemlal, Hanane Ferjouchia, Mostafa Rachik, Nassim Essabah Haraj, Asma Chadli · 2024 · Synthesis lectures on engineering, science, and technology
6. We Certainly Need Real Life Research—But What Is Real Life?
   John P. A. Ioannidis · 2025 · Journal of Evaluation in Clinical Practice
7. Dados de mundo real no processo de tomada de decisão: uma análise sob a perspectiva do sistema brasileiro de saúde suplementar
   André Ballalai, Nadja Souza, Janay Silva, Marina Suavinha, Cláudia Sousa, Tassia Cristina Decimoni · 2019 · Jornal Brasileiro de Economia da Saúde
8. New Technologies in Real-World Data Analysis (RWD): challenges and potential solutions
   R-Pharm, Moscow, Russia, M. Samsonov, N.O. Pogrebnoy, Semantic Hub, Moscow, Russia, E.A. Volskaya · 2020 · Remedium Journal about the Russian market of medicines and medical equipment
9. Incretin-based drugs and hospitalization for heart failure in the clinical practice: A nested case-control study
   Claudia Santucci, Matteo Franchi, Lidia Irene Staszewsky, Carlo La Vecchia, Roberto Latini, Luca Giuseppe Merlino, Giovanni Corrao, Cristina Bosetti · 2018 · Diabetes Research and Clinical Practice
10. Creating a Synthetic Clinical Trial: Comparative Effectiveness Analyses Using an Electronic Medical Record
    Marjorie Glass Zauderer, Aleksandr Grigorenko, Paul May, Nicholas Kastango, Isaac Wagner, Aryeh Caroline, Mark G. Kris · 2019 · JCO Clinical Cancer Informatics
11. Real-World Evidence on the Effectiveness of Pembrolizumab in Patients With Recurrent/Metastatic/Unresectable Head and Neck Squamous Cell Cancer: A Systematic Review and Meta-Analysis
    Meenakshi Meenu, Pravesh Dhiman, Muninder Kumar, Pranita Pradhan, Shivam Pandey · 2025 · Cureus
12. Pharmacovigilance analysis of small bowel bleeding associated with NSAIDs
    Yinghan Deng, Meiting Jiang, Yun Chen, Hongbin Chen · 2025 · Therapeutic Advances in Drug Safety
13. Assessing the replicability of RCTs in RWE emulations
    Jeanette Köppe, Charlotte Micheloud, Stella Erdmann, Rachel Heyard, Leonhard Held · 2025 · BMC Medical Research Methodology
14. Application of the Target Trial Emulation Framework to Studies in the Pediatric Population
    Jenny W. Sun, Daniel B. Horton, Timothy J. Savage, Mehmet Burcu, Sonia Hernández–Dı́az · 2025 · The Journal of Pediatrics
15. Advancing real-world evidence in Brazil: regulatory gaps and global lessons
    Nélio Cezar de Aquino, Cadiele Oliana Reichert, Luís Alberto de Pádua Covas Lage, Hebert Fabrício Culler, Felipe Santa Rosa Roitberg, Vanderson Rocha, Flávia Neves Rocha Alves, Juliana Pereira · 2025 · The Lancet Regional Health - Americas
16. Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy
    Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt · 2026 · British Journal of Clinical Pharmacology
17. Digital Twins in Neonatology: Current Applications and Future Directions: A Narrative Review
    Dimitra Savvidou, Niki Dermitzaki, Maria S. Baltogianni, Aikaterini I. Nikolaou, Vasileios I. Giapros · 2026 · Applied Sciences
18. Statistical Considerations in Proof-of-Concept Studies
    Laurence Colin, Brian P. Smith · 2019 · Springer eBooks
19. Improved quality of physiotherapy care in patients with Whiplash-Associated Disorders: Results based on 16 years of routinely collected data
    Rob A.B. Oostendorp, Hans Elvers, Emiel van Trijffel, Geert M. Rutten, Gwendolijne G. M. Scholten-Peeters, Margot De Kooning, Marjan Laekeman, Jo Nijs, Nathalie Anne Roussel, Han J. A. Samwel · 2022 · Frontiers in Pain Research
20. Research Advance of Causal Inference in Clinical Medicine: A Bibliometrics Analysis via Citespace
    Guoqiang Qin, Jianxiang Wei, Yuehong Sun, Wenwen Du · 2025 · Journal of Multidisciplinary Healthcare
21. Integrative Analysis of Randomized Clinical Trial and Observational Study Data to Inform Post-marketing Safety Decision-Making
    Li‐An Lin, Yafei Zhang, Walter L. Straus, William Yang Wang · 2022 · Therapeutic Innovation & Regulatory Science
22. Clinical observations of acute onset of myopic optic neuropathy in a real-world setting
    Li Liao, Fang Fang, Xiaohua Zhu · 2021 · International Journal of Ophthalmology
23. The Targeted Virtual Control Approach for Single-Arm Clinical Trials with External Controls
    Yixin Fang, Sheng Zhong · 2022 · Statistics in Biopharmaceutical Research
24. Approaches to Assessing the Quality of Observational Studies of Clinical Practice Based on the Big Data Analysis
    Sergey R. Gilyarevsky · 2021 · Rational Pharmacotherapy in Cardiology
25. Exploring the acuity and dependency of adult ward patients following medical emergency team review: The REMAIN study
    Anthony Batterbury · 2022 · Queensland University of Technology
26. Design differences explain variation in results between randomized trials and their non-randomized emulations
    Rachel Heyard, Leonhard Held, Sebastian Schneeweiß, Shirley V. Wang · 2023 · medRxiv
27. Channeling of New Neuropsychiatric Drugs—Impact on Safety and Effectiveness Studies
    Danielle S. Abraham, Thanh Phuong Pham Nguyen, Leah J. Blank, Dylan P. Thibault, Shelly L. Gray, Sean Hennessy, Charles E. Leonard, Daniel A. Weintraub, Allison Wright Willis · 2023 · Neurotherapeutics
28. Complementary evidence on the performance of coronary stents generated by a randomized controlled trial and a worldwide registry
    Alexandre Gautier, Marco Roffi, Peep Laanmets, Shahzad M. Munir, Fazila Tun‐Nesa Malik, Andrés Íñiguez, Gabriel Maluenda, Shoichi Kuramitsu, Michaël Angioı̈, William C. Wijns et al. · 2023 · American Heart Journal
29. Using real‐world data to predict health outcomes—The prediction design: Application and sample size planning
    Stella Erdmann, Dominic Edelmann, Meinhard Kieser · 2023 · Biometrical Journal
30. Health technology assessments of new specialized therapies: A typology of key challenges and potential policy solutions
    Sarah Wadmann, Malene S. Sørensen, Betina Højgaard · 2024 · Health Policy and Technology
31. Electronic Health Data Categories
    Fidelia Cascini · 2025 · SpringerBriefs in public health
32. Clinical Outcomes of Repeated Sodium Polynucleotide Injections in Knee Osteoarthritis: Large-Scale, Retrospective Cohort Study
    Jiyon Bok, Bongseong Kim, Kyungdo Han, Dong Wook Shin, Hasuk Bae · 2025 · Journal of Clinical Medicine
33. Comparative Effectiveness of Ixekizumab Versus Ustekinumab in Patients With Psoriasis: A Randomized Controlled Trial Replication Using Data From an Observational Study (Shanghai Psoriasis Effectiveness Evaluation Cohort)
    Ning Yu, Lian Cui, Yuye Wang, Yu Wang, Xinyi Song, Qin Yang, Yuling Shi · 2025 · Value in Health
34. Real-world data and evidence: pioneering frontiers in precision oncology
    Jingxin Jiang, Weiwei Pan, Liyang P. Sun, Liwei Pang, Hailang Chen, Jian Huang, W. Chen · 2025 · Journal of Zhejiang University SCIENCE B
35. Building a Robust Investigator‐Initiated Platform: The I‐ CARE Experience
    Julien Kirchgesner, Laurent Beaugerie, Cédric Baumann, Filip J. Baert, Jean‐François Rahier, Daniel Bergemalm, Fiorella Cañete, Bénédicte Caron, Marta Cossignani, Sandra Dias et al. · 2026 · Clinical Pharmacology & Therapeutics
36. Framework for evidence synthesis of traditional, complementary and integrative medicine systems incorporating context and complexity, illustrated by the example of homeopathy
    Robbert A. van Haselen, Martin Loef, Pradeep Kumar Dua, Linda L. D. Zhong, Michael Teut, Janney Wale, RajKumar Manchanda, Stephan Baumgartner · 2026 · Frontiers in Public Health
37. Anticancer activities of macromolecules of marine origin: Clinical evidence
    Aryaman Girish Patwardhan, Moin Merchant, Smit Bhavsar, Harpal Singh Buttar, Maushmi Shailesh Kumar · 2024 · Elsevier eBooks
38. Appropriate Relevancy and Reliability of Real-World Data for the Utilization of Regulatory Submission
    Hideaki Bando, Toshihiro Misumi, Yasutoshi Sakamoto, Yuriko Takeda, Yoshiaki Nakamura, K. Mizuguchi, Yoshihiro Aoyagi, Miki Izumi, Tomohiro Kuroda, Ryu Kasai et al. · 2024 · Clinical Colorectal Cancer
39. Comparative risk of opioid overdose in patients who initiated antibiotics for urinary tract infection while on long-term opioid therapy
    Nazleen F. Khan, Katsiaryna Bykov, Robert J. Glynn, Seanna M. Vine, Joshua J. Gagne · 2024 · American Journal of Epidemiology
40. Epidemiology in Clinical Settings
    Kenneth Jay Rothman, Krista F. Huybrechts, Eleanor J. Murray · 2024
41. Results of a French pilot database of standard of care of chronic subdural hematoma
    Clément Baumgarten, A. Lazard, Elsa Magro, Roche Ph, Olivier Hamel, Claire Haegelen, Emmanuel De Schlichting · 2022 · Neurochirurgie
42. The main gaps for randomised-controlled trials in psychiatry: a bibliometric study
    João Maurício Castaldelli-Maia, Michelle Riba, Dušica Lečić‐Toševski, Prabha S. Chandra, Alfredo H. Cía, Peter J Tyrer, Reinhard Heun, Christopher Paul Szabo · 2020 · GLOBAL PSYCHIATRY ARCHIVES
43. Données et preuves en vie réelle dans l’évaluation des technologies de santé : dans quels cas sont-elles complémentaires, substitutives, ou les seules sources de données par rapport aux essais cliniques ?
    Gérard de Pouvourville, Xavier Armoiry, Aurélie Lavorel, Pascal Bilbault, Philippe Maugendre, Lionel Bensimon, Dan Beziz, Patrick Blin, Isabelle Borget, Stephane Bouée et al. · 2022 · Therapies
44. Building Trust in RWE Will Support Clearer Regulatory Uses
    Gregory W. Daniel · 2019 · Therapeutic Innovation & Regulatory Science
45. Data Mining and Other Informatics Approaches to Pharmacoepidemiology
    Andrew Bate, Gianluca Trifirò, Paul Avillach, Stephen J. W. Evans · 2019 · Pharmacoepidemiology
46. The Concurrent Initiation of Medications Is Associated with Discontinuation of Buprenorphine Treatment for Opioid Use Disorder
    Pengyue Zhang, Chien‐Wei Chiang, Sara K. Quinney, Macarius M. Donneyong, Bo Lü, Lei Frank Huang, Feixiong Cheng · 2020 · medRxiv
47. Reply to Comment on: The Tube Versus Trabeculectomy IRISⓇ Registry Study: Cohort Selection and Follow-up and Comparisons to the Randomized Controlled Trial
    Elizabeth A. Vanner, Catherine Q. Sun, Matthew J. McSoley, Patrice J. Persad, William J. Feuer, Flora Lum, Scott Kelly, Richard K. Parrish Ii, Ta Chen Chang, Steven Jon Gedde · 2021 · American Journal of Ophthalmology
48. Use of Recommended Real-World Methods for Electronic Health Record Data Analysis Has Not Improved Over 10 Years
    Chenyu Li, Abdulrahman M. Alsheikh, Karen A. Robinson, Harold P. Lehmann · 2023 · medRxiv
49. Leveraging Observational Data for Causal Inference
    Sébastien Bailly, Tanujit Dey · 2025 · CHEST Journal
50. Innovation in the Design of Clinical Trials: Necessary for Innovation in Medicine
    Brian P. Smith, Oliver Sander · 2017 · Clinical Pharmacology & Therapeutics
51. Breaking Down Barriers to Effective Patient Care
    Peter H. O’Donnell · 2018 · Clinical Pharmacology & Therapeutics
52. Continuing the Effort to Predict Risk of Future Unplanned Healthcare Use in Older Adults
    Clark DuMontier, Dae Hyun Kim · 2018 · Journal of the American Geriatrics Society
53. Evaluation of Cardio-Metabolic Effects of Treatment with Incretin-Based Therapies in Patients with Type 2 Diabetes
    Olga Montvida · 2018 · Queensland University of Technology
54. Ascertaining vaccine exposure at the brand level using real‐world data
    Tamar Lasky · 2019 · Pharmacoepidemiology and Drug Safety
55. Drs. Singh and Magrey reply
    Marina Magrey, DILPREET KAUR SINGH · 2020 · The Journal of Rheumatology
56. The Main Gaps for Randomized-controlled Trials in Psychiatry: A Bibliometric Study
    João Maurício Castaldelli-Maia, Michelle Riba, Dušica Lečić‐Toševski, Prabha S. Chandra, Alfredo H. Cía, Peter J Tyrer, Reinhard Heun, Christopher Paul Szabo · 2020 · GLOBAL PSYCHIATRY ARCHIVES
57. Machine Learning Methods for Causal Inference with Observational Biomedical Data
    A. Averitt · 2020
58. Mortality Risk of Antipsychotic Augmentation for Adult Depression
    Tobias Gerhard, T. Scott Stroup, Christoph Ulrich Correll, Soko Setoguchi, Brian L. Strom, Cecilia S. Huang, Zhiqiang Tan, Stephen Crystal, Mark Olfson · 2021 · FOCUS The Journal of Lifelong Learning in Psychiatry
59. What can real world evidence contribute to regulatory science in pre and post marketing setting?
    N. Martini, Jamie Sultana, Addis, M. Braga, G. Corrao, A. Campomori, A. Capuano, G. Corrao, R. Gini, G Mazzaglia et al. · 2020
60. Causal Inference with Truncation-by-Death and Unmeasured Confounding
    Yuhao Deng, Yingjun Chang, Xiao‐Hua Zhou · 2021 · arXiv (Cornell University)
61. The irradiated breast: impact on the patient and potential solutions for skin toxicity
    Marie Charlotte Theresia Batenburg · 2022
62. Inmunoterapia en cáncer de pulmón metastásico
    Jésica Storino, M. Cerini, Lorena Lupinacci, Sergio Specterman, Federico Cayol · 2022 · Oncología Clínica
63. Exploring the discrepancies between clinical trials and real-world data by accounting for Selection criteria, Operations, and Measurements of Outcome
    Luca Marzano, Adam S. Darwich, Asaf Dan, Salomon Tendler, Rolf Lewensohn, Luigi De Petris, Jayanth Raghothama, Sebastiaan Meijer · 2024 · medRxiv
64. Quantifying Fit-for-Purpose in Real World Data: Data Grading and FitQ Scores
    Michael L. Jackson, R. Manickam, Dan C. Derieg, Saurabh Gombar, Yen Low · 2024 · medRxiv
65. On the use of RWD in support of regulatory submission in drug development
    Shein‐Chung Chow, Peijin Wang · 2024 · Journal of Biopharmaceutical Statistics
66. Comparative Effectiveness of Robot-Assisted Prostatectomy Versus Open Surgery: A High Dimensional Propensity Score Matched Cohort Study in a Nationwide Claims Database
    G. Robert, Patrick Blin, Franck Bladou, Jérémy Jové, Eric N. Ouattara, Magali Rouyer, Cécile Droz‐Perroteau, Laurent Piazza, Nathalie Préaubert · 2024 · SSRN Electronic Journal
67. Evidence-Based Medicine in Theory and Practice: Epistemological and Normative Issues
    Wendy Rogers, Katrina Hutchison · 2024 · Springer eBooks
68. Cancer registry as external control data for regulatory submission in Japan
    Hideaki Bando, Natsuko Tsuda Okita, Yasutoshi Sakamoto, Hiroki Sokuoka, Yoshiaki Nakamura, T. Hashimoto, Toshihiro Misumi, Yasuhiro Takeda, Y. Aoyagi, K. Mizuguchi et al. · 2024 · ESMO Real World Data and Digital Oncology
69. Machine learning approach for detection of MACE events within clinical trial data
    John A. Spanias, Robbie Buderi, Pierre-Louis Bourlon, Christopher Tso, Caleb E. Strait, David Saunders, Kayleen Deanna Ports, Weixi Chen, Rahul Jain, Bhargav Koduru et al. · 2024 · Journal of Biopharmaceutical Statistics
70. Methods to Estimate When to Stop a Treatment and to Compare Treatment Durations Using Observational Data: A Methodological Review
    Peiyu Hao, Sally G. Yaacoub, Raphaël Porcher · 2025 · SSRN Electronic Journal
71. Comparative Risks of Opioid Overdose in Patients on Oxycodone Initiating Selective Serotonin Reuptake Inhibitors
    Katsiaryna Bykov, C. Andrew Basham, Nazleen F. Khan, Robert J. Glynn, Shruti Belitkar, Seanna M. Vine, Sungho Bea, Brian T. Bateman, Krista F. Huybrechts · 2025 · Epidemiology
72. Evidence-Based Medicine in Theory and Practice: Epistemological and Normative Issues
    Wendy Rogers, Katrina Hutchison · 2025 · Springer eBooks
73. Emulation of placebo-controlled index trials using observational data with cloning, censoring and weighting: Empirical assessment of constraints and credibility
    Anna‐Janina Stephan, Gerard Portela, Raisa Levin, Nils Krüger, Sebastian Schneeweiß, Rishi J. Desai · 2025 · medRxiv
74. Clinical parameters associated with blood pressure in patients with primary open-angle glaucoma and exfoliation glaucoma
    Ayumu Akagi, Kaito Narimoto, Kanta Ueda, Noriko Koizumi, Naoki Okumura, Masaki Tanito · 2025 · Graefe s Archive for Clinical and Experimental Ophthalmology
75. κ=0.97: A Practical Framework Any Hospital Can Implement for Research-Grade Data Quality
    Denisse Martínez-Ríos, Juan Carlos Moreno-Rojas, Adrián Martínez-Ríos, Guillermo Díaz Terán-Aguilera, Carlos Eduardo Lulé-Martínez, Dámaso Hernández-López · 2025 · Research Square
76. Additional file 1 of Comparative effectiveness and safety of pharmaceuticals assessed in observational studies compared with randomized controlled trials
    Hong, Yoon Duk, Jeroen Paul Jansen, John Guerino, Marc L. Berger, William H. Crown, Wim Goettsch, Mullins, C. Daniel, Willke, Richard J., Lucinda Strycker Orsini · 2021 · Figshare
77. Additional file 1 of Real-world data emulating randomized controlled trials of non-vitamin K antagonist oral anticoagulants in patients with venous thromboembolism
    Yoon, Dongwon, Jeong, Han Eol, Sohee Park, You, Seng Chan, Bang, Soo-Mee, Shin, Ju-Young · 2023 · Figshare
78. Additional file 2 of Comparative effectiveness and safety of pharmaceuticals assessed in observational studies compared with randomized controlled trials
    Hong, Yoon Duk, Jeroen Paul Jansen, John Guerino, Marc L. Berger, William H. Crown, Wim Goettsch, Mullins, C. Daniel, Willke, Richard J., Lucinda Strycker Orsini · 2021 · Figshare
79. Additional file 3 of Comparative effectiveness and safety of pharmaceuticals assessed in observational studies compared with randomized controlled trials
    Hong, Yoon Duk, Jeroen Paul Jansen, John Guerino, Marc L. Berger, William H. Crown, Wim Goettsch, Mullins, C. Daniel, Willke, Richard J., Lucinda Strycker Orsini · 2021 · Figshare
80. Leveraging the Estimand Framework for Integrated Evidence Planning
    Wentian Guo, Lisa V. Hampson, Rima lzem, Alice Wang, Na Yang, Qiong Du, Chen Lu, Jonathan Siegel · 2025 · Springer series in pharmaceutical statistics
81. Real-World Cardiovascular Research Using the German IQVIA Disease Analyzer Database: Methods, Evidence, and Limitations (2000–2025)
    Karel Kostev, Marcel Konrad, Mark Lüdde · 2026 · Journal of Cardiovascular Development and Disease
82. Leveraging real-world data in evidence-based caries research: a meta-epidemiological study
    Sicheng Wu, Man Kei Chan, Edward Chin Man Lo, May Chun Mei Wong · 2026 · Journal of Evidence Based Dental Practice
83. Patterns of Alarm Fatigue and Their Predictors Among Nurses in Intensive Care Units: A Latent Profile Analysis
    Fu Sheng Yang, Rui Tai, Qian Yu, Qian Qi, Qiuli Wang, Ying Pu, Fang Fang · 2026 · Nursing and Health Sciences
84. Integration of Real-World Data into Clinical Trials: An Interdisciplinary Discussion from Regulatory and Practical Perspectives
    Jeanette Köppe, Anja E. Schiel, Christoph Gerlinger, Heiko Götte, Dominic Edelmann, Stella Erdmann · 2026 · Das Gesundheitswesen
85. The role of generative AI in enhancing predictive modeling for cost-effectiveness analysis in healthcare
    Aanuoluwapo Clement David-Olawade, Ayodele Osunmakinde, Folasayo I Ayoola, Eghosasere Egbon, David B. Olawade · 2026 · Digital engineering.
86. Where is the patient in the records? Evaluating physiotherapists’ first visit in occupational health primary care pathway for low back pain
    Maija Paukkunen, Birgitta E. Öberg, Jaro Ilari Karppinen, Leena Ala‐Mursula, Katja Ryynänen, Riikka Holopainen, Allan Abbott · 2026 · BMJ Open Quality
87. Sources of Data Used in Pharmacoepidemiology and Pharmacovigilance
    Tichawona Chinzowu, Prasad S. Nishtala · 2026 · Elsevier eBooks
88. Human keratin matrix use and wound healing outcomes in post-acute care of pressure ulcers: Evidence from a Bayesian real-world study
    Zwelithini Tunyiswa, Sasha Frade, Ryan Dirks, Howard Walthall · 2026 · International Journal of Tissue Repair
89. Real-World Early Outcomes of the Avalus Aortic Valve: Results From 1250 Patients in the Avalus Clinical confidencE Registry
    Lennart L.W. Vanglabeke, Tom Verbelen, Jean‐Christian Roussel, Christian Lildal Carranza, Lenard Conradi, Koen Cathenis, Giovanni Troise, Julien Guihaire, Juan Bustamante‐Munguira, Bart Meuris et al. · 2026 · Annals of Thoracic Surgery Short Reports
90. Diversity in clinical Trials: The example of systemic lupus erythematosus
    Andrew M. Bevan, Nora Carroll, Garrick L Wallstrom, Sudhakar Sridharan · 2026 · Contemporary Clinical Trials Communications
91. Big data–driven observational evidence in Korea: challenges in interpreting non-randomized studies
    Jong Han Choi · 2026 · Journal of Evidence-Based Practice
92. Émulation d'essais randomisés à partir de données observationnelles : revue méthodologique et applications
    Noémie Simon‐Tillaux · 2024
93. Données de santé, dynamiques et enjeux de souveraineté
    Erwan Pinilla · 2023
94. When evidence meets artificial intelligence
    Gustavo Adolfo Cruz-Suarez, Daniela Hincapie-Ayala, Felipe Ocampo Osorio, María Camila Gómez-Ayala, Sergio Alzate‐Ricaurte, Fredy Ariza, Santiago Esteban, Sohyeon Jeon, Leo Anthony Celi · 2026 · The Lancet Regional Health - Americas
95. The economic burden of KCNT1-related disorders in the United States: insights from caregiver-reported and EMR-derived data
    Amanda Abuhl, Brad Bryan, Megan Wright, Allison Rosenberg, Justin West, Sarah Drislane · 2026 · BMC Health Services Research
96. Efficacy and safety of second-line fluorouracil, leucovorin, and irinotecan plus ramucirumab according to prior first-line regimens in metastatic colorectal cancer: a multicenter retrospective study
    Toshinori Yanagawa, Kozo Kataoka, Hiroki Osumi, Mitsuhiro Furuta, Zhenxin Rao, Ayako Imada, Yuko Fukumoto, Jihyung Song, Kazuma Ito, Kei Kimura et al. · 2026 · International Journal of Clinical Oncology
97. Cost, context, and confounding: rethinking real-world data generation and interpretation in advanced NSCLC
    Mehmet Mutlu Çatlı, Arif Hakan Önder · 2026 · The Oncologist
98. Association between first-trimester cell-free fetal DNA levels and the risk of preterm birth and low birth weight: A propensity score-matched cohort study
    Xiaosa Wang, Hui Shao, Junjiang Wu, Guofeng Yin · 2026 · PLoS ONE
99. Interpreting Glucagon-Like Peptide-1 Receptor Agonist–Associated Cough in Observational Data—Reply
    Tyler J. Gallagher, Albert Li, Anca M. Barbu · 2026 · JAMA Otolaryngology–Head & Neck Surgery
100. Applications of Pharmacoepidemiology and Pharmacovigilance Studies
     Tichawona Chinzowu, Prasad S. Nishtala · 2026 · Elsevier eBooks