When and how can real world data analyses substitute for randomized controlled trials?

Cited by (316)

Items 301–316 of 316

1. Real-World Comparative Effectiveness and Safety of Immune Checkpoint Inhibitors in Advanced Renal Cell Carcinoma: A Systematic Review
   Chin Hang Yiu, Gwyneth Yuet Yin Leung, Isabelle C. Lee, Christine Y. Lu · 2026 · Targeted Oncology
2. Real-world outcomes of second-line pembrolizumab in urothelial carcinoma: a multicenter analysis from the Campania Oncological Network (ROC)
   Rosa Tambaro, Gabriele Calvanese, Andrea Muto, Luigi Formisano, Giuseppe Di Lorenzo, Carlo Buonerba, Davide Bosso, Francesco Sabbatino, Elisabetta Coppola, Marilena Di Napoli et al. · 2026 · BMC Cancer
3. Propranolol and Neurodevelopment in Infantile Hemangioma: Reassuring Signals From Real‐World Data
   Alain Taı̈eb · 2026 · JEADV Clinical Practice
4. Discharge Opioid Dosing and New Opioid Use Disorder After Elective Surgery in Opioid-Naive Adults: An Emulated Target Trial
   Yu-Chia (Sam) Hsu, Hezkiel A. Nanda, Joel F. Farley, Paul E. Drawz, Genevieve B. Melton, Christopher James Tignanelli, Bronwyn J. Southwell, Eric D. Weinhandl, Wendy St. Peter · 2026 · Journal of Surgical Research
5. Fragmented Data, Fragmented Decisions: Integrating Knowledge Systems in Modern Pharmacotherapy
   Alhasan Alsahti Ahmed, Xintong Fan, Al Imran, Changbiao Li, Yu Zhang, Qingyu Wang · 2026 · Research Square
6. Medical Affairs in the Age of Complexity: From Scientific Support to Strategic Enterprise Integrator
   Mussa Arvani · 2026 · Pharmaceutical Medicine
7. Analytical methods in real-world data/evidence (RWD/E): a critical review
   Idrisa Kiryowa, V. Draguns, Mohamed Said Boulkrane · 2026 · Real-World Data & Evidence
8. Real-World Impact of Remote Patient Management on Care Consumption and Care Time in Heart Failure: Retrospective Cohort Study
   Wessel William Nieuwenhuys, Mayke Maria Christina Josephina van Leunen, Jeroen A. A. van de Pol, Frederique Jantine Hafkamp, Ruud F. Spee, René A. Tio, Mathias Funk, Hareld Kemps · 2026 · JMIR Formative Research
9. Durability of Blood Pressure Reduction After Renal Denervation in Resistant Hypertension: Mid‐Term Real‐World Outcomes From Kuwait
   Yahya E. Alansari, Baha S. Abed, Bara S. Abed, Maryam AlQouba, Abdulwahab Alsayegh, Abdullah Nabeel AlAwadi, FS ROOMI, Mohamed Mehana, budour almandeel, Othman Alothman et al. · 2026 · Journal of Clinical Hypertension
10. Changes in evidence used for FDA Novel Drug Approvals: 2016-2024
    Aditya P. Narayan, Veronica L. Irvin, Amanda Jeanette Koong, S.M. Song, Robert M. Kaplan · 2026 · PLoS ONE
11. Pharmaceutical Innovation as a Co-Evolving System of Excipients, Devices, Data, and Regulation
    Andréas Müller, Stefan Weber, Julia Hoffmann, Lukas Schneider, Tobias Klein · 2025 · Journal of Applied Pharmaceutical Technologies and Systems
12. Are target trial emulation studies a valid method of evaluating MCS devices in patients with cardiogenic shock?
    Graham Nichol, Karen Adams, Nicole Chicoine Mooney, Thomas W. Carton, Kenta Nakamura · 2026 · American Heart Journal
13. From Biological Mechanisms to Causal Inference: Quantitative Systems Pharmacology and Causal Frameworks in Drug Development
    Thomas Klabunde, Ramon Hernandez Vecino, Piet H. van der Graaf, Tommaso Andreani · 2026 · Clinical Pharmacology & Therapeutics
14. Real-World Evidence as a Driver of Precision Oncology and Personalized Therapeutic Sequencing in Later-Line Metastatic Colorectal Cancer
    Carlo Signorelli · 2026 · Cancers
15. Stratified Safety Evaluation Framework for Natural Products Based on New Approach Methodologies in Integrative Medicine: A Narrative Review
    Manzhu Cao, Xiaoyan Duan, Jie Li, Ziqi Zhou, Hongtao Jin · 2026 · Future Integrative Medicine
16. Real‐World Databases in Diabetes: A Systematic Review
    Jonah J C Thomas, Anna Meffen, Alessandro Rizzi, Andrew P. Kingsnorth, Beatrice A. Pieri, Ying He, Shirley Konnor, Clare L. Gillies, Kamlesh K. Khunti, Jonathan Valabhji et al. · 2026 · Diabetes/Metabolism Research and Reviews