Flavylium‐ and Silylrhodapolymethines In Excitation Multiplexing
Open accessAbstract
Creation of a flavylium polymethine dye set enabled selection of two fluorophores that match common lasers for exciting in the near‐IR II region. Using these, researchers cast a broad net to catch any wavelength emission in the near‐IR II region, and relied on selective excitation to multiplex; this is a paradigm shift away from multiplexing via discrimination of emission wavelengths. Excitation multiplexing with flavylium dyes is a new and exciting strategy, but not yet a perfect one; it requires discrete water soluble fluorophores, including one that is turned on at 808 nm.
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JuloFlav7 and MeOFlav7 SWIR dyes are applicable for multispectral imaging purposes.
“An adjustment of spectral properties by a heterocycle modification on a 7-substituted flavone intermediate allowed the development of JuloFlav7 and MeOFlav7 SWIR dyes that are applicable for multispectral imaging purposes.40”
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- Authors
- Tian, C., & Burgess, K.
- Affiliations
- Texas A&M University (US)
- Corresponding author
- Burgess, Kevin
- Venue
- ChemPhotoChem
- Publisher
- Wiley
- Published
- 2021-05-26
- Volume
- 5
- Issue
- 8
- Pages
- 702-704
- ISSN
- 2367-0932 (ISSN-L)
- PMC
- PMC9997688
- OpenAlex
- W3165752642
- Cited by
- 7
- References
- 6
- Citations by year
- 2025: 1 · 2024: 3 · 2022: 2 · 2021: 1
- FWCI
- 0.46
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- ChemPhotoChem (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Cancer Prevention and Research Institute of Texas (RP170144, RP180875)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Photochemistry and Electron Transfer Studies
- Keywords
- near-infrared II, water-soluble fluorophores, 808 nm excitation, selective excitation
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