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Cited by 73Maternal Mental Health During Pregnancy and PostpartumGrief, Bereavement, and Mental HealthPsychotherapy Techniques and Applications

Preliminary open trial of interpersonal counseling for subsyndromal depression following miscarriage

Neugebauer, Richard, Kline, Jennie, Bleiberg, Kathryn, Baxi, Laxmi, Markowitz, John C., Rosing, Mark, Levin, Bruce, Keith, Jessica·2007·Depression and Anxiety
DOI 10.1002/da.20150
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Abstract

Miscarriage occurs in 10-20% of clinically recognized pregnancies and is associated with two- to fourfold increases in depressive symptoms. No counseling programs for depressed miscarrying women have been manualized or evaluated for safety and efficacy. We investigated whether depressive symptoms decline substantially among miscarrying women receiving one to six weekly sessions of manualized, telephone-administered interpersonal counseling (IPC), a variant of interpersonal psychotherapy (IPT) in an open trial. Depressive symptom levels were measured with the Center for Epidemiologic Studies-Depression (CES-D) scale. Of 65 women evaluated, 24 were study eligible; 17 consented to participate. Change in symptom levels was evaluated by comparing baseline to postintervention CES-D scores in an intention to treat (ITT) sample (n=17) and a completer subsample (n=9). The latter sample comprised women reevaluated postintervention. In the ITT sample, the CES-D mean score declined from 25.4 to 18.8 [mean within-subject change=6.6, 95% confidence interval (CI)=1.4-11.6]; in the completer subsample, it declined from 23.6 to 11.2 (mean within-subject change=12.3, 95% CI=4.0-20.7). Findings from this small open trial suggest that IPC decreases depressive symptoms after miscarriage. A randomized, controlled trial of IPC's safety and efficacy with depressed miscarrying women is warranted.

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  • Only a few randomized controlled studies have been carried out for women after prenatal loss, and most have been limited by being aimed at outcomes of depression and psychiatric disorder rather than grief itself.

    “Only a few randomized controlled studies have been carried out for women after prenatal loss, and most of these have been limited by being aimed at outcomes of depression and psychiatric disorder rather than grief itself.61-63”

    From Complicated grief after perinatal loss (2012) · cites this paper as [61]

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Authors
Neugebauer, R., Kline, J., Bleiberg, K., Baxi, L., Markowitz, J. C., Rosing, M., Levin, B., & Keith, J.
Affiliations
  • New York State Psychiatric Institute (US)
  • Cornell University (US)
  • Columbia University (US)
  • St. Barnabas Hospital (US)
Corresponding author
Neugebauer, Richard
ORCID
Venue
Depression and Anxiety
Publisher
Hindawi Limited
Published
2007
Volume
24
Issue
3
Pages
219-222
ISSN
  • 1091-4269 (ISSN-L)
  • 1520-6394
DOI
10.1002/da.20150
OpenAlex
W2037679158
Cited by
73
References
21
Citations by year
2025: 1 · 2024: 3 · 2023: 15 · 2022: 3 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 5 · 2017: 5 · 2016: 3 · 2015: 3 · 2014: 5 · 2013: 5 · 2012: 5
FWCI
1.67
Type
journal article
Language
en
Open access
closed
Licence
doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 3165 d)
Locations
  • Depression and Anxiety (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r03mh059179-02)
  • National Institute of Mental Health (1 R03 MH59179-01A1)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
  • Social Sciences › Psychology › Clinical Psychology › Grief, Bereavement, and Mental Health
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords
miscarriage, subthreshold depression, interpersonal counseling, interpersonal psychotherapy, depressive symptoms, postpartum depression, manualized intervention
MeSH terms
Abortion, Spontaneous, Adolescent, Adult, Counseling, Depression, Female, Humans, Interpersonal Relations, Pregnancy, Pregnancy Outcome, Psychotherapy, Severity of Illness Index

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