The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Self-medication with alcohol or drugs for mood and anxiety disorders: A narrative review of the epidemiological literature
Open accessAbstract
BACKGROUND: The comorbidity of mood and anxiety disorders (MD and AD) with substance use disorders (SUD) is common. One explanation for this comorbidity is the self-medication hypothesis, which posits that individuals with MD or AD use substances to cope with the difficult symptoms associated with the disorder. Over time, self-medication (SM) can develop into an independent SUD. This narrative review will present the prevalence and correlates of SM with alcohol and/or drugs for MD and AD and the relationship between SM and subsequent SUD using both cross-sectional and longitudinal epidemiological data. METHODS: Scopus and PsycINFO were searched from January 1997 to April 2018 to identify original research articles that examined the prevalence and correlates of SM and the temporal relationship between MD/AD and SUD in the general population (n = 22). RESULTS: The prevalence of SM with alcohol and/or drugs among those with MD or AD ranged from 21.9% to 24.1%. Male sex, younger age, being separated, divorced or widowed, and being Caucasian were characteristics associated with higher proportions of respondents endorsing SM with alcohol/drugs for MD and AD. Longitudinal data supports the temporal onset of primary MD/AD and secondary SUD among those who self-report SM. CONCLUSION: Providing and promoting alternate coping strategies for those with MD/AD may reduce SM, the development of SUD, and the comorbidity of MD/AD with SUD. The concurrent treatment of MD/AD and substance use is the current "gold standard" model of care, and the results of this review support its use.
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Cites
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The Self-Medication Hypothesis of Substance Use Disorders: A Reconsideration and Recent Applications
Khantzian, E. J. (1997) · Harvard Review of Psychiatry · doi:10.3109/10673229709030550 · Cited by 3,242 · cited 1×
“The self-medication hypothesis (SMH) is one mechanism that can explain the comorbidity between MD/AD and SUD (Khantzian, 1985,1997).”
BackgroundGrant, B. F., Stinson, F. S., Dawson, D. A., Chou, S. P., Dufour, M. C., Compton, W., Pickering, R. P., & Kaplan, K. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.8.807 · Cited by 2,889
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The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence
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“The self-medication hypothesis (SMH) is one mechanism that can explain the comorbidity between MD/AD and SUD (Khantzian, 1985,1997).”
BackgroundKessler, R. C. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830160031005 · Cited by 2,085
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Cited by
Diamond, L. M., & Alley, J. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104720 · Cited by 412
Yu, R., Nevado-Holgado, A. J., Molero, Y., D’Onofrio, B. M., Larsson, H., Howard, L. M., & Fazel, S. (2019) · PLOS Medicine · doi:10.1371/journal.pmed.1002995 · Cited by 152
Addiction, Anhedonia, and Comorbid Mood Disorder. A Narrative Review
Destoop, M., Morrens, M., Coppens, V., & Dom, G. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00311 · Cited by 85
Troxel, W. M., Rodriguez, A., Seelam, R., Tucker, J. S., Shih, R. A., Dong, L., & D’Amico, E. J. (2021) · Sleep · doi:10.1093/sleep/zsab102 · Cited by 45
Child and adolescent social withdrawal predict adult psychosocial adjustment: A meta-analysis
Gazelle, H., Shafer Lundin, J. K., Lei, H., Cao, H., & Litchfield, M. (2024) · Frontiers in Developmental Psychology · doi:10.3389/fdpys.2024.1408166 · Cited by 16
Metadata
- Authors
- Turner, S., Mota, N., Bolton, J., & Sareen, J.
- Venue
- Depression and Anxiety
- Publisher
- Wiley
- Published
- 2018-07-12
- Volume
- 35
- Issue
- 9
- Pages
- 851-860
- ISSN
- 1091-4269 (ISSN-L)
- OpenAlex
- W2849064358
- Cited by
- 432
- References
- 53
- FWCI
- 5.31
- Type
- journal article
- Language
- en
- Open access
- hybrid
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