The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Brain‐derived neurotrophic factor and the development of structural neuronal connectivity
Open accessAbstract
During development, neural networks are established in a highly organized manner, which persists throughout life. Neurotrophins play crucial roles in the developing nervous system. Among the neurotrophins, brain‐derived neurotrophic factor (BDNF) is highly conserved in gene structure and function during vertebrate evolution, and serves an important role during brain development and in synaptic plasticity. BDNF participates in the formation of appropriate synaptic connections in the brain, and disruptions in this process contribute to disorders of cognitive function. In this review, we first briefly highlight current knowledge on the expression, regulation, and secretion of BDNF. Further, we provide an overview of the possible actions of BDNF in the development of neural circuits, with an emphasis on presynaptic actions of BDNF during the structural development of central neurons. © 2010 Wiley Periodicals, Inc. Develop Neurobiol 2010
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Metadata
- Authors
- Cohen‐Cory, S., Kidane, A. H., Shirkey, N. J., & Marshak, S.
- Venue
- Developmental Neurobiology
- Publisher
- Wiley
- Published
- 2010-02-22
- Volume
- 70
- Issue
- 5
- Pages
- 271-288
- ISSN
- 1932-8451 (ISSN-L)
- 1932-846X
- OpenAlex
- W1975682269
- Cited by
- 589
- References
- 18
- FWCI
- 13.23
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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