The DOI matches its Crossref record; 260 of the 260 references it cites were found in a registry or an index.
Squalene – biochemistry, molecular biology, process biotechnology, and applications
Abstract
Squalene is a natural triterpene and an important intermediate of sterol and hopanoid biosynthesis in various types of cell from bacteria to human. Synthesis and further conversion of squalene are key steps in the metabolism of sterols and related components. Here we summarize the recent knowledge of squalene biochemistry, its molecular properties, and its physiological effects. We compare squalene biosynthetic pathways in different cell types and describe biotechnological strategies to isolate this lipid. Finally, applications of squalene in nutrition, pharmacy, and medicine are discussed.
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Cites
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High-value products from microalgae—their development and commercialisation
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Advances in Microalgae-Derived Phytosterols for Functional Food and Pharmaceutical Applications
Luo, X., Su, P., & Zhang, W. (2015) · Marine Drugs · doi:10.3390/md13074231 · Cited by 226
Terpenoids and Their Biosynthesis in Cyanobacteria
Pattanaik, B., & Lindberg, P. (2015) · Life · doi:10.3390/life5010269 · Cited by 173
Gohil, N., Bhattacharjee, G., Khambhati, K., Braddick, D., & Singh, V. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00050 · Cited by 121
“Squalene (C30H50), an intermediate of cholesterol biosynthesis, is a naturally occurring highly unsaturated triterpenic hydrocarbon compound that forms solely via the mevalonic acid (MVA) or 2-C-methyl-D-erythritol 4-phosphate (MEP) pathways (Spanova and Daum, 2011; Popa et al., 2015; Rani et al., 2018).”
Background
Metadata
- Authors
- Spanova, M., & Daum, G.
- Venue
- European Journal of Lipid Science and Technology
- Publisher
- Wiley
- Published
- 2011-09-15
- Volume
- 113
- Issue
- 11
- Pages
- 1299-1320
- ISSN
- 1438-7697 (ISSN-L)
- 1438-9312
- OpenAlex
- W1967251058
- Cited by
- 268
- References
- 260
- FWCI
- 3.06
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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