The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Immune function of microglia
Abstract
During the past decade, mechanisms involved in the immune surveillance of the central nervous system (CNS) have moved to the forefront of neuropathological research mainly because of the recognition that most neurological disorders involve activation and, possibly, dysregulation of microglia, the intrinsic macrophages of the CNS. Increasing evidence indicates that, in addition to their well‐established phagocytic function, microglia may also participate in the regulation of non specific inflammation as well as adaptive immune responses. This article focuses on the signals regulating microglia innate immune functions, the role of microglia in antigen presentation, and their possible involvement in the development of CNS immunopathology. GLIA 36:165–179, 2001. © 2001 Wiley‐Liss, Inc.
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Cites
A Toll-like receptor recognizes bacterial DNA
Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) · Nature · doi:10.1038/35047123 · Cited by 6,491 · cited 2×
“Among these, TLR-2 recognizes products such as peptidoglycans and lipopeptide from gram-positive bacteria and zymosan from yeast, TLR-4 is the receptor for LPS, and TLR-9 recognizes bacterial DNA (Hemmi et al., 2000; Kaisho and Akira, 2000).”
BackgroundInflammation and Alzheimer’s disease
Akiyama, H. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00124-x · Cited by 4,514
Streit, W. J., Walter, S. A., & Pennell, N. A. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00069-0 · Cited by 1,096
Brain microglia constitutively express β-2 integrins
Akiyama, H., & McGeer, P. L. (1990) · Journal of Neuroimmunology · doi:10.1016/0165-5728(90)90055-r · Cited by 430
Linehan, S. A., Martínez-Pomares, L., Stahl, P. D., & Gordon, S. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.12.1961 · Cited by 285 · cited 1×
“…receptors are expressed by macrophages within the meninges, choroid plexuses, and perivascular spaces, whereas resting microglia express low to moderate levels of CR3 (Akiyama and McGeer, 1990), but no CD14 (Dick et al., 1997; Nadeau and Rivest, 2000) or mannose receptor (Linehan et al., 1999).”
BackgroundBernardo, A., Levi, G., & Minghetti, L. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00110.x · Cited by 222
Cited by
Neuroglial activation and neuroinflammation in the brain of patients with autism
Vargas, D. L., Nascimbene, C., Krishnan, C., Zimmerman, A. W., & Pardo, C. A. (2005) · Annals of Neurology · doi:10.1002/ana.20315 · Cited by 2,149
Microglial physiology: unique stimuli, specialized responses
Ransohoff, R. M., & Perry, V. H. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132528 · Cited by 1,858
Microglia as a source and target of cytokines
Hanisch, U. (2002) · Glia · doi:10.1002/glia.10161 · Cited by 1,645
Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
Jin, R., Yang, G., & Li, G. (2010) · Journal of Leukocyte Biology · doi:10.1189/jlb.1109766 · Cited by 1,521
-Synuclein in Parkinson's Disease
Stefanis, L. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a009399 · Cited by 1,446
Metadata
- Authors
- Aloisi, F.
- Venue
- Glia
- Publisher
- Wiley
- Published
- 2001-10-02
- Volume
- 36
- Issue
- 2
- Pages
- 165-179
- ISSN
- 0894-1491 (ISSN-L)
- 1098-1136
- OpenAlex
- W1977604451
- Cited by
- 1,280
- References
- 6
- FWCI
- 21.52
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
