Depression, cognitive impairment and function in Alzheimer's disease
Abstract
Depression is very common in patients with dementia but the relationship is very complex. Depression is regarded as a cause of excess disability in persons with dementia and contributes to their functional decline. The assessment of depression in dementia patients, however, has been difficult in that the validity of self‐reported depression in patients with dementia has been questioned. This study was done to investigate whether self‐reported depression by persons with dementia (using the GDS) is related to their functional abilities as rated by a family caregiver (using the IADL scale) above and beyond demographic variables. This study was conducted at the Detroit Satellite of the Michigan Alzheimer's Disease Research Center. There were 141 participants, 67% were African American and 33% were European American. Statistical analyses included a correlational and multiple regression approach to determine the predictive relationships of cognitive and depressive symptoms above and beyond the influence of demographic variables and cognition. The results of the study further support the notion that depression in dementia is significantly related to functional decline but, more importantly, that self‐reported depression in patients with dementia can be valuable information in understanding patients' functioning. Copyright © 2001 John Wiley & Sons, Ltd.
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Depression symptoms are common for older adults with memory difficulties.
“Depression symptoms are common for older adults with memory difficulties and their caregivers.”
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- Authors
- Espiritu, D. A. V., Rashid, H., Mast, B. T., Fitzgerald, J., Steinberg, J., & Lichtenberg, P. A.
- Affiliations
- Wayne State University (US)
- Harper University Hospital (US)
- Corresponding author
- Espiritu, Doree Ann V.
- Venue
- International Journal of Geriatric Psychiatry
- Publisher
- Wiley
- Published
- 2001-11
- Volume
- 16
- Issue
- 11
- Pages
- 1098-1103
- ISSN
- 0885-6230 (ISSN-L)
- 1099-1166
- OpenAlex
- W2084782094
- Cited by
- 80
- References
- 20
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 4 · 2014: 4 · 2013: 3 · 2012: 1
- FWCI
- 2.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- depression, Alzheimer's disease, dementia, functional decline, self-reported depression, Global Deterioration Scale, instrumental activities of daily living, family caregivers, cognitive impairment, disability
- MeSH terms
- Activities of Daily Living, Aged, Aged, 80 and over, Alzheimer Disease, Cognition Disorders, Demography, Depression, Female, Persons with Disabilities, Humans, Male, Middle Aged, Psychometrics, Surveys and Questionnaires, Self-Assessment, Caregivers
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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