Cited by 80Dementia and Cognitive Impairment ResearchAging, Health, and DisabilityAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Depression, cognitive impairment and function in Alzheimer's disease

Espiritu, Doree Ann V., Rashid, Harun, Mast, Benjamin T., Fitzgerald, Joe, Steinberg, Joel, Lichtenberg, Peter A.·2001·International Journal of Geriatric Psychiatry

Abstract

Depression is very common in patients with dementia but the relationship is very complex. Depression is regarded as a cause of excess disability in persons with dementia and contributes to their functional decline. The assessment of depression in dementia patients, however, has been difficult in that the validity of self‐reported depression in patients with dementia has been questioned. This study was done to investigate whether self‐reported depression by persons with dementia (using the GDS) is related to their functional abilities as rated by a family caregiver (using the IADL scale) above and beyond demographic variables. This study was conducted at the Detroit Satellite of the Michigan Alzheimer's Disease Research Center. There were 141 participants, 67% were African American and 33% were European American. Statistical analyses included a correlational and multiple regression approach to determine the predictive relationships of cognitive and depressive symptoms above and beyond the influence of demographic variables and cognition. The results of the study further support the notion that depression in dementia is significantly related to functional decline but, more importantly, that self‐reported depression in patients with dementia can be valuable information in understanding patients' functioning. Copyright © 2001 John Wiley & Sons, Ltd.

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Crossref · 10.1002/gps.476

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Authors
Espiritu, D. A. V., Rashid, H., Mast, B. T., Fitzgerald, J., Steinberg, J., & Lichtenberg, P. A.
Affiliations
  • Wayne State University (US)
  • Harper University Hospital (US)
Corresponding author
Espiritu, Doree Ann V.
Venue
International Journal of Geriatric Psychiatry
Publisher
Wiley
Published
2001-11
Volume
16
Issue
11
Pages
1098-1103
ISSN
  • 0885-6230 (ISSN-L)
  • 1099-1166
OpenAlex
W2084782094
Cited by
80
References
20
Citations by year
2024: 3 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 1 · 2015: 4 · 2014: 4 · 2013: 3 · 2012: 1
FWCI
2.77
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
depression, Alzheimer's disease, dementia, functional decline, self-reported depression, Global Deterioration Scale, instrumental activities of daily living, family caregivers, cognitive impairment, disability
MeSH terms
Activities of Daily Living, Aged, Aged, 80 and over, Alzheimer Disease, Cognition Disorders, Demography, Depression, Female, Persons with Disabilities, Humans, Male, Middle Aged, Psychometrics, Surveys and Questionnaires, Self-Assessment, Caregivers

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