Increased mortality and hospital readmission risk in patients with dementia and a history of cardiovascular disease: Results from a nationwide registry linkage study
Open accessAbstract
OBJECTIVE: To evaluate the impact of cardiovascular disease (CVD) on mortality and readmission risk in patients with dementia. METHODS: Prospective hospital-based cohort of 59 194 patients with dementia admitted to hospital or visiting a day-clinic between 2000 and 2010. Patients were divided in those with and without a history of CVD (ie, previous admission for CVD; coronary heart disease, heart failure, stroke, atrial fibrillation, or other CVD). Absolute mortality risks (ARs), median survival times, and hazard ratios (adjusted for age, sex, and comorbidity) were calculated. RESULTS: Three-year ARs and HRs were higher, and survival times were shorter among patients visiting a day-clinic with a history of CVD than in those without. The differences were less pronounced for inpatients. Readmission risk was further increased in the presence of CVD in both day clinic and inpatients. CONCLUSION: Clinicians need to be more aware of worse prognosis of the population with CVD and dementia.
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Mortality is a definitive outcome, which can illustrate both ill-health and effectiveness of care and symptom management throughout the trajectory of an illness.
“Mortality is a definitive outcome, which can illustrate both ill-health and effectiveness of care and symptom management throughout the trajectory of an illness [16,23].”
From The Impact of demographic, socio-economic and geographic factors on mortality risk among people living with dementia in England (2002–2016) (2021) · cites this paper as [16]
Effective treatment and management of dementia and comorbidities has been illustrated to impact survival rates among people living with dementia.
“Effective treatment and management of dementia and comorbidities has been illustrated to impact survival rates among PLWD [16,17].”
From The Impact of demographic, socio-economic and geographic factors on mortality risk among people living with dementia in England (2002–2016) (2021) · cites this paper as [16]
As dementia progresses, people living with dementia are likely to need greater levels of healthcare involvement.
“As dementia progresses, and health deteriorates, PLWD are likely to need greater levels of healthcare involvement, both in relation to dementia, and comorbidities [16].”
From The Impact of demographic, socio-economic and geographic factors on mortality risk among people living with dementia in England (2002–2016) (2021) · cites this paper as [16]
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- Authors
- van de Vorst, I. E., Vaartjes, I., Bots, M. L., & Koek, H. L.
- Affiliations
- Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Utrecht The Netherlands
- University Medical Center Utrecht (NL)
- Venue
- International Journal of Geriatric Psychiatry
- Publisher
- Wiley
- Published
- 2018-12-21
- Volume
- 34
- Issue
- 3
- Pages
- 488-496
- ISSN
- 0885-6230 (ISSN-L)
- 1099-1166
- OpenAlex
- W2902985626
- Cited by
- 8
- References
- 30
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 1 · 2021: 2 · 2020: 1
- FWCI
- 0.59
- Type
- journal article
- Language
- en
- Open access
- green
- dspace.library.uu.nl
- Licence
- Locations
- International Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Utrecht University Repository (Utrecht University) (submittedVersion)
- Funders
- Hartstichting
- Alzheimer Nederland (WE.03‐2012‐38)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Keywords
- dementia, cardiovascular disease, mortality, hospital readmission, prognosis, day clinic, coronary artery disease, heart failure, stroke, atrial fibrillation, survival time, comorbidities
- MeSH terms
- Aged, Ambulatory Care Facilities, Cardiovascular Diseases, Dementia, Female, Heart Failure, Humans, Inpatients, Male, Middle Aged, Patient Readmission, Prospective Studies, Registries, Risk Factors, Cohort Studies, Comorbidity, Proportional Hazards Models, Stroke
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