The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Test-retest reproducibility of the default-mode network in healthy individuals
Open accessAbstract
Independent component analysis (ICA) of functional magnetic resonance imaging (fMRI) time-series reveals distinct coactivation patterns in the resting brain representing spatially coherent spontaneous fluctuations of the fMRI signal. Among these patterns, the so-called default-mode network (DMN) has been attributed to the ongoing mental activity of the brain during wakeful resting state. Studies suggest that many neuropsychiatric diseases disconnect brain areas belonging to the DMN. The potential use of the DMN as functional imaging marker for individuals at risk for these diseases, however, requires that the components of the DMN are reproducible over time in healthy individuals. In this study, we assessed the reproducibility of the DMN components within and between imaging sessions in 18 healthy young subjects (mean age, 27.5 years) who were scanned three times with two resting state scans during each session at 3.0 T field strength. Statistical analysis of fMRI time-series was done using ICA implemented with BrainVoyager QX. At all three sessions the essential components of the DMN could be identified in each individual. Spatial extent of DMN activity and size of overlap within and between sessions were most reproducible for the anterior and posterior cingulate gyrus. The degree of reproducibility of the DMN agrees with the degree of reproducibility found with motor paradigms. We conclude that DMN coactivation patterns are reproducible in healthy young subjects. Therefore, these data can serve as basis to further explore the effects of aging and neuropsychiatric diseases on the DMN of the brain.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Several recent studies of testretest reproducibility for time-concatenated ICA (i.e., our ICA method in this study) of resting state fMRI, however, indicate very good reproducibility when the resting state sessions are performed within one year of each other [Guo et al., 2012;Meindl et al., 2010;Zuo et al., 2010].”
From Specific default mode subnetworks support mentalizing as revealed through opposing network recruitment by social and semantic FMRI tasks: Mentalizing and Default-Mode Subnetworks (2015) · cites this paper as Meindl et al., 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
Functional connectivity in the motor cortex of resting human brain using echo‐planar mri
Biswal, B., Zerrin Yetkin, F., Haughton, V. M., & Hyde, J. S. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910340409 · Cited by 9,812
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0135058100 · Cited by 6,358
Consistent resting-state networks across healthy subjects
Damoiseaux, J. S., Rombouts, S. A. R. B., Barkhof, F., Scheltens, P., Stam, C. J., Smith, S. M., & Beckmann, C. F. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601417103 · Cited by 4,326
Greicius, M. D., Srivastava, G., Reiss, A. L., & Menon, V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308627101 · Cited by 3,684
Wandering minds: the default network and stimulus-independent thought
Mason, M. F., Norton, M. I., Van Horn, J. D., Wegner, D. M., Grafton, S. T., & Macrae, C. N. (2007) · Science · doi:10.1126/science.1131295 · Cited by 2,792
Squire, L. R., Stark, C. E. L., & Clark, R. E. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144130 · Cited by 2,680
Greicius, M. D., Flores, B. H., Menon, V., Glover, G. H., Solvason, H. B., Kenna, H., Reiss, A. L., & Schatzberg, A. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.020 · Cited by 2,214
Electrophysiological signatures of resting state networks in the human brain
Mantini, D., Perrucci, M. G., Del Gratta, C., Romani, G. L., & Corbetta, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700668104 · Cited by 1,938
Frequencies contributing to functional connectivity in the cerebral cortex in "resting-state" data.
Cordes, D., Haughton, V. M., Arfanakis, K., Carew, J. D., Turski, P. A., Moritz, C. H., Quigley, M., & Meyerand, M. E. (2001) · PubMed Central · Cited by 1,402
Reduced resting-state brain activity in the “default network” in normal aging
Damoiseaux, J. S., Beckmann, C. F., Arigita, E. J. S., Barkhof, F., Scheltens, P., Stam, C. J., Smith, S. M., & Rombouts, S. A. R. B. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm207 · Cited by 1,187 · cited 1×
“The DMN is affected by aging [Damoiseaux et al., 2008] and disrupted in several neuropsychiatric disorders such as mild cognitive impairment [Sorg et al., 2007], Alzheimer’s disease [Greicius et al., 2004], schizophrenia [Zhou et al., 2007], depression [Greicius et al., 2007], and autism [Kennedy…”
BackgroundSimultaneous EEG and fMRI of the alpha rhythm
Goldman, R. I., Stern, J. M., Engel, J., & Cohen, M. S. (2002) · Neuroreport · doi:10.1097/00001756-200212200-00022 · Cited by 1,131
Goebel, R., Esposito, F., & Formisano, E. (2006) · Human Brain Mapping · doi:10.1002/hbm.20249 · Cited by 1,053
Selective changes of resting-state networks in individuals at risk for Alzheimer’s disease
Sorg, C., Riedl, V., Mühlau, M., Calhoun, V. D., Eichele, T., Läer, L., Drzezga, A., Förstl, H., Kurz, A., Zimmer, C., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708803104 · Cited by 1,036
EEG-correlated fMRI of human alpha activity
Laufs, H., Kleinschmidt, A., Beyerle, A., Eger, E., Salek-Haddadi, A., Preibisch, C., & Krakow, K. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00286-6 · Cited by 1,025
Dietrich, O., Raya, J. G., Reeder, S. B., Reiser, M. F., & Schoenberg, S. O. (2007) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.20969 · Cited by 1,001
Self-citationSimultaneous EEG and fMRI of the alpha rhythm
Stern (2002) · Neuroreport · doi:10.1097/01.wnr.0000047685.08940.d0 · Cited by 945
Mapping functionally related regions of brain with functional connectivity MR imaging.
Cordes, D., Haughton, V. M., Arfanakis, K., Wendt, G. J., Turski, P. A., Moritz, C. H., Quigley, M., & Meyerand, M. E. (2000) · PubMed Central · Cited by 908
Failing to deactivate: Resting functional abnormalities in autism
Kennedy, D. P., Redcay, E., & Courchesne, E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600674103 · Cited by 543
van de Ven, V. G., Formisano, E., Prvulovic, D., Röder, C. H., & Linden, D. E. J. (2004) · Human Brain Mapping · doi:10.1002/hbm.20022 · Cited by 538
Alexander, G. E., Chen, K., Pietrini, P., Rapoport, S. I., & Reiman, E. M. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.5.738 · Cited by 532
Self-referential reflective activity and its relationship with rest: a PET study
D’Argembeau, A., Collette, F., der Linden, M. V., Laureys, S., Fiore, G. D., Degueldre, C., Luxen, A., & Salmon, É. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.11.048 · Cited by 498
Independent component analysis of fMRI group studies by self-organizing clustering
Esposito, F., Scarabino, T., Hyvärinen, A., Himberg, J., Formisano, E., Comani, S., Tedeschi, G., Goebel, R., Seifritz, E., & Salle, F. D. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.10.042 · Cited by 367
Zhou, Y., Liang, M., Jiang, T., Tian, L., Liu, Y., Liu, Z., Liu, H., & Kuang, F. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.02.081 · Cited by 295
Functional connections among cortical regions: topography of EEG coherence
Tucker, D. M., Roth, D. L., & Bair, T. B. (1986) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(86)90092-1 · Cited by 183
Rombouts, S. A. R. B., Barkhof, F., Hoogenraad, F. G. C., Sprenger, M., & Scheltens, P. (1998) · Magnetic Resonance Imaging · doi:10.1016/s0730-725x(97)00253-1 · Cited by 169
Loubinoux, I., Carel, C., Alary, F., Boulanouar, K., Viallard, G., MANELFE, C., Rascol, O., Celsis, P., & Chollet, F. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200105000-00014 · Cited by 156
Test-retest analysis with functional MR of the activated area in the human visual cortex.
Rombouts, S. A. R. B., Barkhof, F., Hoogenraad, F. G. C., Sprenger, M., Valk, J., & Scheltens, P. (1997) · PubMed Central · Cited by 130
Tyler, J. L., Strother, S. C., Zatorre, R. J., Alivisatos, B., Worsley, K. J., Dikšić, M., & Yamamoto, Y. (1988) · PubMed · Cited by 80
Reproducibility of activation in four motor paradigms
Havel, P., Braun, B., Rau, S., Tonn, J. C., Fesl, G., Brückmann, H., & Ilmberger, J. (2005) · Journal of Neurology · doi:10.1007/s00415-005-0028-4 · Cited by 62
Flagged first, then by citations
Cited by
Sorted by citations
Dynamic functional connectivity: Promise, issues, and interpretations
Hutchison, R. M., Womelsdorf, T., Allen, E. A., Bandettini, P. A., Calhoun, V. D., Corbetta, M., Della Penna, S., Duyn, J. H., Glover, G. H., Gonzalez-Castillo, J., et al. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.05.079 · Cited by 2,962
The influence of head motion on intrinsic functional connectivity MRI
Van Dijk, K. R. A., Sabuncu, M. R., & Buckner, R. L. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.07.044 · Cited by 2,344
Van Dijk, K. R. A., Hedden, T., Venkataraman, A., Evans, K. C., Lazar, S. W., & Buckner, R. L. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00783.2009 · Cited by 1,844
Zhou, J., Greicius, M. D., Gennatas, E. D., Growdon, M. E., Jang, J. Y., Rabinovici, G. D., Kramer, J. H., Weiner, M., Miller, B. L., & Seeley, W. W. (2010) · Brain · doi:10.1093/brain/awq075 · Cited by 1,016
Zuo, X.-N., Kelly, C., Adelstein, J. S., Klein, D. F., Castellanos, F. X., & Milham, M. P. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.10.080 · Cited by 744
Metadata
- Authors
- Meindl, T., Teipel, S., Elmouden, R., Mueller, S., Koch, W., Dietrich, O., Coates, U., Reiser, M., & Glaser, C.
- Affiliations
- Ludwig-Maximilians-Universität München (DE)
- University of Rostock (DE)
- Venue
- Human Brain Mapping
- Publisher
- Wiley
- Published
- 2009-07-20
- Volume
- 31
- Issue
- 2
- Pages
- 237-246
- ISSN
- 1065-9471 (ISSN-L)
- 1097-0193
- PMC
- PMC6871144
- OpenAlex
- W2082137112
- Cited by
- 220
- References
- 35
- Citations by year
- 2026: 3 · 2024: 5 · 2023: 5 · 2022: 5 · 2021: 17 · 2020: 7 · 2019: 33 · 2018: 4 · 2017: 18 · 2016: 8 · 2015: 12 · 2014: 23 · 2013: 18 · 2012: 22
- FWCI
- 10.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Human Brain Mapping (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
- Keywords
- default mode network, test-retest reproducibility, resting-state fMRI, independent component analysis, spontaneous brain activity, anterior cingulate cortex, posterior cingulate cortex, healthy young adults
- MeSH terms
- Adult, Brain, Brain Mapping, Female, Gyrus Cinguli, Humans, Magnetic Resonance Imaging, Male, Motor Activity, Neural Pathways, Neuropsychological Tests, Signal Processing, Computer-Assisted, Software, Reproducibility of Results, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
