Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial

Lindor, Keith D., Kowdley, Kris V., Heathcote, Jenny E., Harrison, Edwyn M., Jorgensen, Roberta, Angulo, Paul, Lymp, James F., Burgart, Lawrence +1 more·2004·Hepatology
DOI 10.1002/hep.20092

Cited by (727)

Items 501–600 of 727

  1. Fatty Liver Disease
    DINA G. TINIAKOS, Quentin Mark Anstee, Elizabeth M. Brunt, Alastair D. Burt · 2023 · Elsevier eBooks
  2. Ursodeoxycholic Acid for the Treatment of Liver Diseases
    J.-Y. Wang, S.-D. Wu · 2017 · Elsevier eBooks
  3. Study on the Factors Influencing the Extraction of Chenodeoxycholic Acid from Duck Bile Paste by Calcium Salt Method
    Xiangzheng Hu, Na Feng, Jiaqi Zhang · 2018 · Journal of Applied Chemistry
  4. Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis
    Francesco Angelico, Cesare Alessandri, Maria Del Ben, Flavio Lirussi · 2013 · Cochrane Database of Systematic Reviews
  5. Recent advances in the treatment of non-alcoholic fatty liver disease
    Flavia D. Mendes, Keith D. Lindor · 2005 · Expert Opinion on Investigational Drugs
  6. Current treatments in nonalcoholic steatohepatitis
    Dawn McDowell Torres, Stephen A. Harrison · 2007 · Current Treatment Options in Gastroenterology
  7. The Discovery of Obeticholic Acid ( Ocaliva™ ): First‐in‐Class FXR Agonist
    Roberto Pellicciari, Mark Pruzanski, Antimo Gioiello · 2018 · Wiley eBooks
  8. Phase III, multicenter, randomized, double-blind, placebo-controlled study of norursodeoxycholic acid in metabolic dysfunction-associated steatotic liver disease patients
    Veerendra Kumar Panuganti, Chandrasekhar Varma Alluri, Javeed Mohammad, Mamatha Reddy Dundigalla, Pavan Kumar Madala, Sanyasirao KSSVV, Althaf hussain shaik · 2025 · World Journal of Hepatology
  9. Current Treatment Options, Including Diet, Exercise, and Medications
    Mazen Noureddin, Manal F. Abdelmalek · 2023 · Clinics in Liver Disease
  10. Characteristics of intestinal flora in nonobese nonalcoholic fatty liver disease patients and the impact of ursodeoxycholic acid treatment on these features
    Liyan Wang, Jiali Xu, Ningning You, Li Shao, Zhenjie Zhuang, Lili Zhuo, Jing Liu, Junping Shi · 2024 · Lipids
  11. Evolution of characteristics of MASLD with and without diabetes: a meta-analysis of placebo arms
    Han Ah Lee, Hye Ah Lee, Hwi Young Kim · 2024 · Scientific Reports
  12. Novel treatment strategies for patients with nonalcoholic fatty liver disease
    Brian P Lam, Zobair M. Younossi · 2011 · Clinical Investigation
  13. Pathology of Alcoholic and Nonalcoholic Fatty Liver Disease
    Pierre Bédossa, David Erwin Kleiner · 2015 · Springer eBooks
  14. Nonalcoholic Fatty Liver Disease: Review
    Indrajit Kumar Datta, Anisur Rahman, Tareq Mahmud Bhuiyan, Md. Mohsin Kabir · 2012 · BIRDEM Medical Journal
  15. Nonalcoholic Fatty Liver Disease
    Andrea Ewing Reid · 2010 · Elsevier eBooks
  16. Steatohepatitis und Leberzirrhose: Erstmanifestation 23 Jahre nach ejunoilealem Bypass
    P Piringer, Robert Buder, Fritz Firlinger, Christine Kapral, Christian Luft, Wolfgang Sega, F Wewalka, Kurt Lenz · 2007 · Wiener klinische Wochenschrift
  17. Current and novel therapies for the treatment of nonalcoholic steatohepatitis
    David van der Poorten, Jacob George · 2007 · Hepatology International
  18. NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA
    Yara K. Haddad, Diane Vallerand, Antoine Brault, Jean Spénard, Pierre Selim Haddad · 2011 · International Journal of Hepatology
  19. The trials and tribulations of the treatment of nonalcoholic fatty-liver disease
    Seng Khee Gan, Leon Anton Adams, Gerald Francis Watts · 2008 · Current Opinion in Lipidology
  20. New Therapies in Hepatitis C Virus and Chronic Liver Disease: Antifibrotics
    Don C. Rockey · 2006 · Clinics in Liver Disease
  21. Non-alcoholic fatty liver disease
    Rika Jamali, Arsia Jamali · 2010 · KAUMS Journal
  22. Non-alcoholic steatohepatitis (NASH): approaching more tailored and effective therapies.
    Piero Portincasa · 2007 · PubMed
  23. Non‐Alcoholic Fatty Liver Disease
    Christopher Paul Day · 2010
  24. Nonalcoholic Fatty Liver Disease
    Stephen Hugh Caldwell, Curtis Kent Argo, Abdullah M. S. Al‐Osaimi · 2011
  25. The effects of ursodeoxycholic acid on cardiometabolic risk factors: a systematic review and meta-analysis of randomized controlled trials
    Elaheh Rashidbeygi, Niloufar Rasaei, Mohammad Reza Amini, Marieh Salavatizadeh, Mehdi Mohammadizadeh, Azita Hekmatdoost · 2025 · BMC Cardiovascular Disorders
  26. Stéatopathies métaboliques
    Maud Lemoine, Lawrence Serfaty · 2011 · La Presse Médicale
  27. Nonalcoholic Fatty Liver Disease: Pharmacologic and Surgical Options
    Neil D. Parikh, Jawad Ahmad · 2011 · Gastroenterology Clinics of North America
  28. Functional gall-bladder disorders and non-alcoholic fatty liver disease: clinical features and new approaches to therapy
    Мехтиев Сабир Насрединович, О. А. Мехтиева, Z. M. Ibragimova · 2020 · Meditsinskiy sovet = Medical Council
  29. What are the main areas of focus to prevent or treat non‐alcoholic fatty liver disease?
    Asieh Mansour, Azita Hekmatdoost, Parvin Mirmiran · 2019 · Journal of Digestive Diseases
  30. Nonviral Hepatitis
    Kerry Wilbur · 2009 · Journal of Pharmacy Practice
  31. Treatment of fibrosis in nonalcoholic fatty liver disease
    Maarouf A. Hoteit, Frank A. Anania · 2007 · Current Gastroenterology Reports
  32. Current management of patients with nonalcoholic fatty liver disease
    Elzafir B. Elsheikh, Linda L Henry, Zobair M. Younossi · 2013 · Expert Review of Endocrinology & Metabolism
  33. Stéatopathie métabolique : prise en charge
    Alexandre E. Pariente · 2009 · Gastroentérologie Clinique et Biologique
  34. MASLD Pharmacotherapy: Current Standards, Emerging Treatments, and Practical Guidance for Indian Physicians
    Ashish Kumar · 2025 · Journal of the Association of Physicians of India
  35. Ileal FXR Knockdown Ameliorates MASLD Progression in Rats via Modulating Bile Acid Metabolism Mediated by Gut Microbiota
    Junjun Wang, Jiaqi Gao, Qingqing Zhang, Jingyi Lu, Yufei Yang, Xiaobo Cai, Hui Dong, Lungen Lu · 2025 · Journal of Gastroenterology and Hepatology
  36. Development of UHPLC‐MS/MS Method for Evaluation of the Acute Oral Toxicity and Pharmacokinetics of Ursodeoxycholic Acid and Silymarin Combination in Rats
    Mennatallah A. Hammam, Zainab Zakaria, Mahmoud Rabee, Al‐Taher Rabea, Donia E. Hafez, Mohammad Abdel‐Halim, Ahmed Ibrahim Ismail, Azza El‐Sayed Mansy · 2024 · Separation Science Plus
  37. Efficacy and Safety of Obeticholic Acid for Treating Hepatic Steatosis in Patients With Familial Partial Lipodystrophy
    Abhimanyu Garg, Chandna Vasandani, Xilong Li, Claudia Quittner, Takeshi Yokoo · 2025 · The Journal of Clinical Endocrinology & Metabolism
  38. Oxidative Stress and Liver Fibrogenesis
    Erica Novo, Fabio Marra, Maurizio Parola · 2015 · Oxidative stress in applied basic research and clinical practice
  39. Fatty Liver Disease
    Sameer M. Mazhar, Heather M. Patton, Richard T. Scuderi, Takeshi Yokoo, Silvana Castro Faria, Claude B. Sirlin · 2011 · Elsevier eBooks
  40. A Systematic Review of Korean Medicine for Non-Alcoholic Fatty Liver Disease
    Yu‐Ri Lee, Na-kyung Cho, Hong-Sik Choi, Seung-mo Kim, Kyung-soon Kim · 2019 · The Journal of Internal Korean Medicine
  41. A new bile acid treatment for non-alcoholic fatty liver disease
    Wah‐Kheong Chan, Vincent Wai‐Sun Wong · 2019 · The Lancet. Gastroenterology & hepatology
  42. Nonalcoholic steatohepatitis (NASH): therapeutic approaches
    HP Buscher · 2004 · DMW - Deutsche Medizinische Wochenschrift
  43. The PERFECT Study (PEnnel Real liFe Efficacy Clinical Trial), a Double-Blind, Randomized, Multicenter Trial Examining the Efficacy of Biphenyl Dimethyl Dicarboxylate Combined with Garlic Oil in Patients with Transaminase Elevated Chronic Liver Disease
    Hyung Joon Kim, June Sung Lee, Hyun Woong Lee, Mun Young Kim, Soon Woo Nam, Ju Hyun Sohn, Se Hyun Cho, Seung Gyu Yoon, Jin Mo Yang, Chung Kee Park et al. · 2014 · Korean Journal of Medicine
  44. Validity and reliability of the nonalcoholic fatty liver diseases activity score (NAS) in Korean NAFLD patients and its correlation with clinical factors
    Kyung-Hun Lee, Sang Hoon Park, Yu-Jin Kim, Kyung Rim Huh, Kwang Seon Min, Sun‐Young Jun, Kyoung Oh Kim, Cheol Hee Park, Taeho Hahn, Kyo-Sang Yoo et al. · 2010 · The Korean Journal of Hepatology
  45. Nonalcoholic fatty liver disease: a review
    Fred F Poordad · 2005 · Expert Opinion on Emerging Drugs
  46. Management of Nonalcoholic Fatty Liver Disease (NAFLD)
    Monjur Ahmed∥ · 2018 · InTech eBooks
  47. High rates of ineligibility for participation in trials of new therapies in non-alcoholic steatohepatitis: a systematic review
    Anna Roskilly, Jessica E. Shearer, Richard Parker, Ian A.C. Rowe · 2019 · European Journal of Gastroenterology & Hepatology
  48. The Impact of Body Weight Change on Liver Histology in Metabolic Dysfunction-Associated Steatotic Liver Disease Across Various Histological Endpoints: A Systematic Review and Meta-Analysis.
    Jayabalan, Dujinthan, Dhakal, Sugam, Chandra, Jeffrey, Fasser, Daniel A., Jeffrey, Gary P., Garas, George, Vilar-Gomez, Eduardo, Calzadilla-Bertot, Luis, Adams, Leon A. · 2026 · American Journal of Gastroenterology
  49. Nonalcoholic Fatty Liver Disease
    Narriane Chaves Pereira de Holanda, Amanda R. L. Oliveira, Nara Carvalho, Bruno L. Souza · 2022 · Springer eBooks
  50. Combined lipid-lowering therapy in patients with nonalcoholic fatty liver disease
    Pavel Vasilievich Seliverstov, Stanislav I. Sitkin, V. Radchenko, Darejan Tsurtsumia, S. Dzhadzhav · 2018 · Vrach
  51. THE EFFECT OF MELATONIN, METFORMIN AND URSODEOXYCHOLIC ACID ON NON-ALCOHOLIC FATTY LIVER DISEASE: A RANDOMIZED, DOUBLE-BLINDED CONTROLLED TRIAL
    Kourosh Mojtahedi, Farahnaz Joukar, Seyyed Fahim, Sara Yeganeh, Mehrnaz Asgharnezhad, Afshin Shafaghi, Saba Fakhrieh Asl, Fariborz Mansour‐Ghanaei · 2023 · Bulletin of Pharmaceutical Sciences Assiut
  52. [Nonalcoholic steatohepatitis: diagnosis, pathogenesis, treatment and prognosis].
    Peter L. M. Jansen · 2005 · PubMed
  53. Therapieoptionen für die nicht-alkoholinduzierte Fettleber und Fettleberhepatitis
    Johannes Kluwe, Ansgar Wilhelm Lohse · 2005 · Der Internist
  54. Management of nonalcoholic steatohepatitis: Pharmacotherapy
    Vlad Ratziu · 2012 · Clinical Liver Disease
  55. Non Alkolik Yağlı Karaciğer Hastalığında Güncel Medikal Tedavi
    Akif Acay · 2015 · Kocatepe Tıp Dergisi
  56. Nonalcoholic fatty liver disease: treatment
    Sang Hoon Park · 2010 · The Korean Journal of Internal Medicine
  57. Ursodeoxycholic acid treatment of hepatic steatosis: a 13C NMR metabolic study
    Patrícia M. Nunes, John Griffith Jones, Anabela Pinto Rolo, Carlos M. Palmeira, Rui A. Carvalho · 2011 · NMR in Biomedicine
  58. Tratamiento de la enfermedad hepática por depósito de grasa
    Marta Cobo Martín, Pedro Luis Fernández-Gil, Javier Crespo · 2008 · Gastroenterología y Hepatología
  59. Non-Alcoholic Fatty Liver Disease and Malignancy as Complications of Insulin Resistance
    Zachary T. Bloomgarden · 2005 · Metabolic Syndrome and Related Disorders
  60. Chemotherapy-Associated Steatohepatitis with Temozolomide and Dexamethasone
    Robert J.H. Miller, Xianyong Sean Gui, Jacob C. Easaw, Roger Y. Tsang · 2012 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  61. Hypertension and hepatic steatosis
    Matthew Brookes, Tariq H Iqbal, Brian T. Cooper · 2008 · Current Hypertension Reports
  62. Interactions between non‐alcoholic fatty liver disease and hepatitis C viral infection
    Zobair M. Younossi · 2004 · Journal of Gastroenterology and Hepatology
  63. 生活習慣と肝臓病：診断と治療の進歩 ＩＶ．非アルコール性脂肪肝炎（ＮＡＳＨ）３．酸化ストレスとＮＡＳＨ
    岡上 武, 光吉博則 · 2006 · Nihon Naika Gakkai Zasshi
  64. Nonalcoholic Fatty Liver Disease
    Emer Fitzpatrick · 2015 · Springer eBooks
  65. Non-Alcoholic Fatty Liver Disease and Cardiovascular Risk
    Tatjána Ábel, János Fehér · 2008 · Hungarian Medical Journal
  66. Acute and Chronic Hepatitis
    Rima L. Fawaz, Maureen M. Jonas · 2021 · Elsevier eBooks
  67. Tratamiento médico de la hepatopatía grasa no alcohólica primaria
    Diego Moreno Sánchez · 2005 · Medicina Clínica
  68. Treatment of NASH with ursodeoxycholic acid: Pros and cons. More information in children
    Pietro Vajro, Giulia Paolella, Luca Pierri, Roberta D’Aniello · 2013 · Clinics and Research in Hepatology and Gastroenterology
  69. Non-alcoholic Fatty Liver Disease in Obesity
    Silvia Marinho Ferolla · 2015 · Springer eBooks
  70. Treating the patient with nonalcoholic fatty liver disease
    Amanda J. Chaney · 2015 · The Nurse Practitioner
  71. Неалкогольна жирова хвороба печінки: сучасний погляд на патогенез, діагностику та лікування
    Victoria B. Yagmur · 2013 · GASTROENTEROLOGY
  72. Therapeutic and Preventive Effects of Aqueous Extracts of Arctium lappa L. and Cichorium intybus L. against Fatty Liver in Rats
    Mohammad Jafari Shiran, Saeed Naseri, Tahereh Sadeghian-Rizi, Saeed Khani, Mohammad Shoormij, Seyedeh Simin Dakhilpour · 2022 · Jorjani Biomedicine Journal
  73. “NASH-Worldwide the Commonest Aetiology of Liver Cirrhosis”- a Review Article
    Syeda Nur E Jannat, M M Shahin Ul Islam, Mohammad Majharul Haque, Iftekhar Imam, Dewan Saifuddin Ahmed · 2023 · Bangabandhu Sheikh Mujib Medical College Journal
  74. Non-Alcoholic Fatty Liver Disease
    Elisabetta Bugianesi · 2009 · Frontiers of gastrointestinal research
  75. Is there an effective therapy available for non-alcoholic fatty liver disease?
    Vittorio Di Maso, Stefano Bellentani · 2009 · F1000 Medicine Reports
  76. Pharmacological agents for nonalcoholic steatohepatitis
    Maéva Guillaume, Vlad Ratziu · 2013 · Hepatology International
  77. Pharmacologic Management of Non-Alcoholic Fatty Liver Disease
    George Boon‐Bee Goh · 2014 · Advances in Pharmacoepidemiology & Drug Safety
  78. Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH)
    C. S. Pitchumoni, C. S. Pitchumoni, C. S. Pitchumoni · 2012 · Springer eBooks
  79. Future Treatments of NASH
    Brent A. Neuschwander‐Tetri · 2016 · Current Hepatology Reports
  80. 1. Nonalcoholic Fatty Liver Disease
    Toshinari Takamura · 2013 · Nihon Naika Gakkai Zasshi
  81. Clinical Aspects of Nonalcoholic Fatty Liver Disease
    Noa Mashav, Oren Shibolet · 2014 · Oxidative stress and disease
  82. NASH
    Brent A. Neuschwander‐Tetri · 2006 · Elsevier eBooks
  83. What proportion of people have a follow-up biopsy in randomized trials of treatments for non-alcoholic steatohepatitis?: A systematic review and meta-analysis
    Dimitrios A. Koutoukidis, Elizabeth M. Morris, John A. Henry, Yusra Shammoon, Matthew Zimmerman, Moscho Michalopoulou, Susan Ann Jebb, Paul N Aveyard · 2021 · PLoS ONE
  84. Ursodeoxycholic Acid in Liver Cirrhosis: An Evidence-Based Review
    Kanokwan Pinyopornpanish · 2022 · Springer eBooks
  85. Liver Transplantation for Nonalcoholic Fatty Liver Disease
    Michael Charlton · 2008 · Humana Press eBooks
  86. NUTRIÇÃO NA DOENÇA HEPÁTICA GORDUROSA NÃO ALCOÓLICA E SÍNDROME METABÓLICA: UMA REVISÃO INTEGRATIVA
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  87. Fígado Gordo Não Alcoólico: Revisão da Literatura
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  88. Aspectos relevantes de la enfermedad por hígado graso no alcohólico
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  89. Identification of Shared Gene Signatures in Different Stages of Nonalcoholic Fatty Liver Disease Using Integrated Microarray Datasets
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    Filiz Akyüz, Kadir Demır, Uğur Çevikbaş, Atilla Ökten · 2004 · Journal of Gastroenterology and Hepatology
  91. The Effect of Endocrine Diseases on Liver Function
    Anthony J. DeSantis, Andrés T. Blei · 2007
  92. Non-Alcoholic Fatty Liver Disease : A clinical and histopathological study
    Mattias Ekstedt · 2008 · DiVA (Linkoping University)
  93. Endoplasmic reticulum stress in nonalcoholic fatty liver disease
    Fabienne Foufelle, Pascal Ferré · 2015
  94. Is vitamin e or ursodeoxycholic acid a valid treatment option for nonalcoholic fatty liver disease in 2016?
    M Beaton, Bandar Al-Judaibi · 2016 · Saudi Journal of Gastroenterology
  95. Two faces of the same coin non alcoholic fatty liver disease; with and without diabetes: Comparative clinico pathological analysis: A cross sectional observational study
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  97. Nonalcoholic Fatty Liver Disease in Adults: The Impact of Diet and Other Therapeutic Interventions on Clinical and Histological Outcomes
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  98. Insulin-resistance and non-alcoholic fatty liver, is there a cause-effect relationship between both conditions?
    Raúl Orlando Calderín Bouza, Carlos Domínguez Álvarez, Pedro Evelio Velbes Marquetti, Luis Alberto Pérez Blanco, Eduardo Cabrera Rode, Neraldo Orlandi González · 2009 · DOAJ (DOAJ: Directory of Open Access Journals)
  99. Enfermedad del hígado graso no alcohólico y riesgo cardiovascular
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  100. Non-Alcoholic Fatty Liver Disease
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