Apoptotic cells attenuate fulminant hepatitis by priming Kupffer cells to produce interleukin-10 through membrane-bound TGF-β

Interleukin-10 and the Interleukin-10 Receptor

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TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES

Li, M. O., Wan, Y. Y., Sanjabi, S., Robertson, A.-K. L., & Flavell, R. A. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.24.021605.090737 · Cited by 2,199 · see citing works

A blast from the past: clearance of apoptotic cells regulates immune responses

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Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

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Liver: An organ with predominant innate immunity

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The Inflammatory Response to Cell Death

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Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF‐β

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Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF-β1

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Kupffer Cell Engulfment of Apoptotic Bodies Stimulates Death Ligand and Cytokine Expression

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Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity

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TGF-β Released by Apoptotic T Cells Contributes to an Immunosuppressive Milieu

Chen, W., Frank, M., Jin, W., & Wahl, S. M. (2001) · Immunity · doi:10.1016/s1074-7613(01)00147-9 · Cited by 417 · see citing works

Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge

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Phosphatidylserine recognition by phagocytes: a view to a kill

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Mechanism of T cell tolerance induction by murine hepatic Kupffer cells

You, Q., Cheng, L., Kedl, R. M., & Ju, C. (2008) · Hepatology · doi:10.1002/hep.22395 · Cited by 333 · see citing works

The liver as a site of T-cell apoptosis: graveyard, or killing field?

Crispe, I. N., Dao, T., Klugewitz, K., Mehal, W. Z., & Metz, D. P. (2000) · Immunological Reviews · doi:10.1034/j.1600-0528.2002.017412.x · Cited by 321 · see citing works

Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance

Diehl, L., Schurich, A., Grochtmann, R., Hegenbarth, S., Chen, L., & Knolle, P. A. (2008) · Hepatology · doi:10.1002/hep.21965 · Cited by 291 · see citing works

Inhibitory Effects of Apoptotic Cell Ingestion upon Endotoxin-Driven Myeloid Dendritic Cell Maturation

Stuart, L. M., Lucas, M., Simpson, C., Lamb, J. R., Savill, J., & Lacy‐Hulbert, A. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.4.1627 · Cited by 275 · see citing works

CD3-specific antibody–induced immune tolerance involves transforming growth factor-β from phagocytes digesting apoptotic T cells

Perruche, S., Zhang, P., Liu, Y., Saas, P., Bluestone, J., & Chen, W.-J. (2008) · Nature Medicine · doi:10.1038/nm1749 · Cited by 265 · see citing works

Interleukin‐10 targets p38 MAPK to modulate ARE‐dependent TNF mRNA translation and limit intestinal pathology

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Interleukin-10 Expression in Macrophages during Phagocytosis of Apoptotic Cells Is Mediated by Homeodomain Proteins Pbx1 and Prep-1

Chung, E. Y., Liu, J., Homma, Y., Zhang, Y., Brendolan, A., Saggese, M., Han, J., Silverstein, R. L., Selleri, L., & Ma, X. (2007) · Immunity · doi:10.1016/j.immuni.2007.11.014 · Cited by 249 · see citing works

SHP-2 Phosphatase Negatively Regulates the TRIF Adaptor Protein-Dependent Type I Interferon and Proinflammatory Cytokine Production

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Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver

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Lipopolysaccharide Induces Rapid Production of IL-10 by Monocytes in the Presence of Apoptotic Neutrophils

Byrne, A. M., & Reen, D. J. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.4.1968 · Cited by 228 · see citing works

High-content single-cell drug screening with phosphospecific flow cytometry

Krutzik, P. O., Crane, J., Clutter, M. R., & Nolan, G. P. (2007) · Nature Chemical Biology · doi:10.1038/nchembio.2007.59 · Cited by 205 · see citing works

CD69+CD4+CD25− T Cells, a New Subset of Regulatory T Cells, Suppress T Cell Proliferation through Membrane-Bound TGF-β1

Han, Y., Guo, Q., Zhang, M., Chen, Z., & Cao, X. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.1.111 · Cited by 188 · see citing works

Role of the liver in regulating numbers of circulating neutrophils

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The roles of innate immune cells in liver injury and regeneration.

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Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides

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Passive and Active Mechanisms Trap Activated CD8+ T Cells in the Liver

John, B., & Crispe, I. N. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.9.5222 · Cited by 157 · see citing works

Scavenger receptors on liver Kupffer cells mediate the in vivo uptake of oxidatively damaged red blood cells in mice

Terpstra, V., & van Berkel, T. J. C. (2000) · Blood · doi:10.1182/blood.v95.6.2157 · Cited by 153 · see citing works

Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages

Jiang, W., Sun, R., Wei, H., & Tian, Z. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504570102 · Cited by 153 · see citing works

The Liver: A Special Case in Transplantation Tolerance

Benseler, V., McCaughan, G. W., Schlitt, H. J., Bishop, G. A., Bowen, D. G., & Bertolino, P. (2007) · Seminars in Liver Disease · doi:10.1055/s-2007-979471 · Cited by 146 · see citing works

The consequences of apoptosis in autoimmunity

Lleò, A., Selmi, C. F., Invernizzi, P., Podda, M., & Gershwin, M. E. (2008) · Journal of Autoimmunity · doi:10.1016/j.jaut.2008.04.009 · Cited by 140 · see citing works

Requirements for Apoptotic Cell Contact in Regulation of Macrophage Responses

Lucas, M., Stuart, L. M., Zhang, A., Hodivala‐Dilke, K., Febbraio, M., Silverstein, R. L., Savill, J., & Lacy‐Hulbert, A. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.6.4047 · Cited by 133 · see citing works

Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen‐presenting dendritic cells

Schildberg, F. A., Hegenbarth, S. I., Schumak, B., Limmer, A., & Knolle, P. A. (2008) · European Journal of Immunology · doi:10.1002/eji.200738060 · Cited by 115 · see citing works

Intrahepatic immunity: a tale of two sites?

Bowen, D. G., McCaughan, G. W., & Bertolino, P. (2005) · Trends in Immunology · doi:10.1016/j.it.2005.08.005 · Cited by 102 · see citing works

Murine Liver Antigen Presenting Cells Control Suppressor Activity of CD4+CD25+ Regulatory T Cells *

Wiegard, C., Frenzel, C., Herkel, J., Kallen, K.-J., Schmitt, E., & Lohse, A. W. (2005) · Hepatology · doi:10.1002/hep.20756 · Cited by 97 · see citing works

Role of Kupffer cells in the induction of tolerance of orthotopic liver transplantation in rats

Chen, Y., Liu, Z., Liang, S., Luan, X., Long, F., Chen, J., Peng, Y., Yan, L., & Gong, J. (2008) · Liver Transplantation · doi:10.1002/lt.21450 · Cited by 86 · see citing works

Allograft tolerance induced by donor apoptotic lymphocytes requires phagocytosis in the recipient

Sun, E., Gao, Y., Chen, J., Roberts, A. I., Wang, X., Chen, Z., & Shi, Y. (2004) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401500 · Cited by 71 · see citing works

Tumor Apoptotic Bodies Inhibit CTL Responses and Antitumor Immunity via Membrane-Bound Transforming Growth Factor-β1 Inducing CD8+ T-Cell Anergy and CD4+ Tr1 Cell Responses

Xie, Y., Bai, O., Yuan, J., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0496 · Cited by 66 · see citing works

Peripheral T-Cell Tolerance Associated with Prostate Cancer Is Independent from CD4+CD25+ Regulatory T Cells

Degl'Innocenti, E., Grioni, M., Capuano, G., Jachetti, E., Freschi, M., Bertilaccio, M. T. S., Michelini, R. H., Doglioni, C., & Bellone, M. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-2429 · Cited by 62 · see citing works

A Defect in Marco Expression Contributes to Systemic Lupus Erythematosus Development via Failure to Clear Apoptotic Cells

Rogers, N. J., Lees, M., Gabriel, L., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0801320 · Cited by 56 · see citing works

The β2 integrin CD11b attenuates polyinosinic:Polycytidylic acid–induced hepatitis by negatively regulating natural killer cell functions #

Zhang, M., Han, Y., Han, C., et al. (2009) · Hepatology · doi:10.1002/hep.23168 · Cited by 29 · see citing works

Presence of Membrane-Bound TGF-β1 and Its Regulation by IL-2-Activated Immune Cell-Derived IFN-γ in Head and Neck Squamous Cell Carcinoma Cell Lines

Ahn, Y., Lee, J.-C., Sung, M., & Heo, D. S. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803725 · Cited by 18 · see citing works

The Liver Mediates Apoptotic Cell‐Induced Immune Regulation

Wang, Y., Gao, Y., Yuan, X., Xia, W., Luo, Y., Sun, E., & Chen, Z. (2008) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.2008.02141.x · Cited by 8 · see citing works

Inflammation and immunity in liver homeostasis and disease: a nexus of hepatocytes, nonparenchymal cells and immune cells

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Inflammation in Alcohol-Associated Hepatitis: Pathogenesis and Therapeutic Targets

Feng, D., Hwang, S., Guillot, A., Wang, Y., Guan, Y., Chen, C., Maccioni, L., & Gao, B. (2024) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2024.04.009 · Cited by 44 · see citing works

MicroRNA-345-3p is a potential biomarker and ameliorates rheumatoid arthritis by reducing the release of proinflammatory cytokines

Ma, J., Zhao, W., Pei, X., et al. (2023) · Journal of Orthopaedic Surgery and Research · doi:10.1186/s13018-023-03797-3 · Cited by 3 · see citing works

Dihydrocapsaicin suppresses proinflammatory cytokines expression by enhancing nuclear factor IA in a NF-κB-dependent manner

Zhao, J., Hu, Y., Huang, C., et al. (2016) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2016.06.002 · Cited by 21 · see citing works

Effects of Proinflammatory Cytokines in the Heart

Zhang, C. (2004) · Life Science Research

Induction of inducible nitric oxide synthase and proinflammatory cytokines expression by o,p′-DDT in macrophages

Kim, J. (2004) · Toxicology Letters · doi:10.1016/j.toxlet.2003.12.001 · Cited by 45 · see citing works

Proinflammatory Cytokines Mediate GPCR Dysfunction

Mohan, M. L., Vasudevan, N. T., & Prasad, S. V. N. (2017) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000456 · Cited by 21 · see citing works