Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Sun, Xiaofang, Ou, Zhanhui, Chen, Ruochan, Niu, Xiaohua, Chen, De, Kang, Rui, Tang, Daolin·2016·Hepatology

DOI 10.1002/hep.28251

Cited by (1,001)

Items 501–600 of 1,001

Sipeimine ameliorates PM2.5-induced lung injury by inhibiting ferroptosis via the PI3K/Akt/Nrf2 pathway: A network pharmacology approach
Yilan Wang, Zherui Shen, Sijing Zhao, Demei Huang, Xiaomin Wang, Yongcan Wu, Caixia Pei, Shihua Shi, Nan Jia, Yacong He et al. · 2022 · Ecotoxicology and Environmental Safety
Ferroptosis and its role in cardiomyopathy
Danlei Li, Wenhu Pi, Zhenzhu Sun, Xiaoman Liu, Jianjun Jiang · 2022 · Biomedicine & Pharmacotherapy
Ferroptosis in ulcerative colitis: Potential mechanisms and promising therapeutic targets
Dan Long, Chenhan Mao, Yingtao Huang, Yin Xu, Ying Zhu · 2024 · Biomedicine & Pharmacotherapy
Identification of a Ferroptosis-Related Signature Model Including mRNAs and lncRNAs for Predicting Prognosis and Immune Activity in Hepatocellular Carcinoma
Zian Chen, Hui Tian, Dong-Mei Yao, Yuan Zhang, Zhijie Feng, Chuan‐Jie Yang · 2021 · Frontiers in Oncology
Ferroptosis: At the Crossroad of Gemcitabine Resistance and Tumorigenesis in Pancreatic Cancer
Jianhui Yang, Jin Xu, Bo Zhang, Zhen Tan, Qingcai Meng, Jie Hua, Jiang Liu, Wei Wang, Si Shi, Xianjun Yu et al. · 2021 · International Journal of Molecular Sciences
The Potential Mechanisms by which Artemisinin and Its Derivatives Induce Ferroptosis in the Treatment of Cancer
Yingying Hu, Nan Guo, Ting Yang, Jianghong Yan, Wenjun Wang, Xiang Li · 2022 · Oxidative Medicine and Cellular Longevity
Multifaceted Roles of Ferroptosis in Lung Diseases
Yi Li, Ying Yang, Yongfeng Yang · 2022 · Frontiers in Molecular Biosciences
The Cancer Antioxidant Regulation System in Therapeutic Resistance
Xuanhao Gu, Chunyang Mu, Rujia Zheng, Zhe Zhang, Qi Zhang, Tingbo Liang · 2024 · Antioxidants
Autophagy, an accomplice or antagonist of drug resistance in HCC?
Yafei Wu, Jigang Zhang, Qin Li · 2021 · Cell Death and Disease
Iron Administration Overcomes Resistance to Erastin-Mediated Ferroptosis in Ovarian Cancer Cells
Anna Martina Battaglia, Alessandro Sacco, Ida Daniela Perrotta, Maria Concetta Faniello, Mariangela Scalise, Daniele Torella, Sonia Levi, Francesco Saverio Costanzo, Flavia Biamonte · 2022 · Frontiers in Oncology
Ferroptosis in hepatocellular carcinoma: from bench to bedside
Daolin Tang, Guido Kroemer, Rui Kang · 2023 · Hepatology
Targeted inhibition of Rev‐erb‐α/β limits ferroptosis to ameliorate folic acid‐induced acute kidney injury
Lianxia Guo, Tianpeng Zhang, Fei Wang, Xun Chen, Haiman Xu, Cui Zhou, Min Chen, Fangjun Yu, Shuai Wang, Deguang Yang et al. · 2020 · British Journal of Pharmacology
Natural Products as Inducers of Non-Canonical Cell Death: A Weapon against Cancer
Giulia Greco, Elena Catanzaro, Carmela Fimognari · 2021 · Cancers
SIRT6 silencing overcomes resistance to sorafenib by promoting ferroptosis in gastric cancer
Shunv Cai, Shuang Fu, Weikang Zhang, Xiaohong Yuan, Yun Cheng, Jun Fang · 2021 · Biochemical and Biophysical Research Communications
Iron and liver cancer: an inseparable connection
Keisuke Hino, Izumi Yanatori, Yuichi Hara, Sohji Nishina · 2021 · FEBS Journal
FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner
Jong Woo Kim, Min-Ju Kim, Tae-Hee Han, Ji-Yoon Lee, Sangok Kim, Hye‐Rin Kim, Kyoung‐Jin Oh, Won Kon Kim, Baek‐Soo Han, Kwang‐Hee Bae et al. · 2023 · Cell Death and Disease
BHQ-Cyanine-Based “Off–On” Long-Circulating Assembly as a Ferroptosis Amplifier for Cancer Treatment: A Lipid-Peroxidation Burst Device
Mangmang Sang, Renjie Luo, Yidan Bai, Jun Dou, Zhongtao Zhang, Fulei Liu, Feng Feng, Wenyuan Liu · 2019 · ACS Applied Materials & Interfaces
Gastrodin Inhibits H2O2-Induced Ferroptosis through Its Antioxidative Effect in Rat Glioma Cell Line C6
Ting Jiang, Jun Chu, Hejuntao Chen, Hui Cheng, Jingjing Su, Xuncui Wang, Yin Cao, Shasha Tian, Qinglin Li · 2020 · Biological and Pharmaceutical Bulletin
Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats
Jun Su, Chongting Gao, Ling Xie, Ying Fan, Yilan Shen, Qunwei Huang, Niansong Wang, Youhua Xu, Nizhi Yang, Dingkun Gui · 2021 · Frontiers in Pharmacology
Ferroptosis and Its Potential Role in the Nervous System Diseases
Yiyang Zhou, Wei Lin, Tian Rao, Jinyu Zheng, Tianlei Zhang, Min Zhang, Zhenlang Lin · 2022 · Journal of Inflammation Research
Propofol Protects Myocardium From Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through the AKT/p53 Signaling Pathway
Shengqiang Li, Zhen Lei, Xiaomei Yang, Meng Liang Zhao, Yonghao Hou, Di Wang, Shuhai Tang, Jingxin Li, Jingui Yu · 2022 · Frontiers in Pharmacology
Ferroptosis in cardiovascular disease
Guoqing Liu, Xiaoyong Xie, Wang Liao, Siyuan Chen, Rumao Zhong, Jiahui Qin, Peichun He, Jian Xie · 2023 · Biomedicine & Pharmacotherapy
Emerging Mechanisms and Targeted Therapy of Ferroptosis in Neurological Diseases and Neuro-oncology
Yajie Wang, Bufu Tang, Jinyu Zhu, Junchao Yu, Junguo Hui, Shuiwei Xia, Jiansong Ji · 2022 · International Journal of Biological Sciences
Ferroptosis-related small-molecule compounds in cancer therapy: Strategies and applications
Linzhou Yin, Pengyu Liu, Yue Jin, Zunxi Ning, Yiren Yang, Huiyuan Gao · 2022 · European Journal of Medicinal Chemistry
Targeting ferroptosis: a novel insight against myocardial infarction and ischemia–reperfusion injuries
Xuejie Han, Jie Zhang, Jian Liu, Hongxia Wang, Fenghe Du, Xiangjun Zeng, Caixia Guo · 2022 · APOPTOSIS
The interplay of oncogenic signaling, oxidative stress and ferroptosis in cancer
Wentao Zeng, Xiaohang Long, Pu‐Ste Liu, Xin Xie · 2023 · International Journal of Cancer
Targeting cell death in NAFLD: mechanisms and targeted therapies
Huili Xu, Shengrong Wan, Ying An, Qi Wu, Yi-hang Xing, Chen-Hao Deng, Pingping Zhang, Yang Long, Bu-tuo Xu, Zongzhe Jiang · 2024 · Cell Death Discovery
Ferroptosis Driver SOCS1 and Suppressor FTH1 Independently Correlate With M1 and M2 Macrophage Infiltration in Head and Neck Squamous Cell Carcinoma
Zhangwei Hu, Yihui Wen, Renqiang Ma, Lin Chen, Xue‐Lan Zeng, Weiping Wen, Wei Sun · 2021 · Frontiers in Cell and Developmental Biology
Targeting Regulated Cell Death with Pharmacological Small Molecules: An Update on Autophagy-Dependent Cell Death, Ferroptosis, and Necroptosis in Cancer
Junhao Wu, Jing Ye, Qiang Xie, Bo Liu, Ming Liu · 2022 · Journal of Medicinal Chemistry
Ferroptosis‐Mediated Synergistic Therapy of Hypertrophic Scarring Based on Metal–Organic Framework Microneedle Patch
Bin Zhao, Wenfeng Guo, Xiaomeng Zhou, Yumeng Xue, Tianyi Wang, Qiang Li, Lili Tan, Li Shang · 2023 · Advanced Functional Materials
Targeting Nrf2 in ischemia-reperfusion alleviation: From signaling networks to therapeutic targeting
Mehrdokht Sadrkhanloo, Maliheh Entezari, Sima Orouei, Amirhossein Zabolian, Amirreza Mirzaie, Amin Maghsoudloo, Rasoul Raesi, Neda Asadi, Mehrdad Hashemi, Ali Zarrabi et al. · 2022 · Life Sciences
The epigenetic regulatory mechanisms of ferroptosis and its implications for biological processes and diseases
Molin Yang, Hanshen Luo, Xin Yi, Xiang Wei, D. Jiang · 2023 · MedComm
Double-edged roles of ferroptosis in endometriosis and endometriosis-related infertility
Yangshuo Li, Yalun He, Wen Cheng, Zhihao Zhou, Zhexin Ni, Chaoqin Yu · 2023 · Cell Death Discovery
Molecular Mechanisms of Ferroptosis and Its Role in Pulmonary Disease
Ningning Tao, Kang Li, Jingjing Liu · 2020 · Oxidative Medicine and Cellular Longevity
GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail
Ling Chen, Qidong Cai, Rui Yang, Haiyan Wang, Huli Ling, Tiansheng Li, Na Liu, Zuli Wang, Jingyue Sun, Tania Tao et al. · 2023 · Proceedings of the National Academy of Sciences
Antioxidant Systems as Modulators of Ferroptosis: Focus on Transcription Factors
Carolina Punziano, Silvia Trombetti, Elena Cesaro, Michela Grosso, Raffaella Faraonio · 2024 · Antioxidants
Targeting the regulation of iron homeostasis as a potential therapeutic strategy for nonalcoholic fatty liver disease
Yutong Sui, Xue Geng, Ziwei Wang, Jing Zhang, Yanqun Yang, Ziyu Meng · 2024 · Metabolism
Mechanism of Action and Therapeutic Implications of Nrf2/HO-1 in Inflammatory Bowel Disease
Lingling Yuan, Yingyi Wang, Na Li, Xuli Yang, Xuhui Sun, Huai’e Tian, Yi Zhang · 2024 · Antioxidants
Cellular and Molecular Pathophysiology of Gestational Diabetes
Johnatan Torres‐Torres, Irma Eloísa Monroy-Muñoz, Javier Perez Duran, Juan Mario Solis‐Paredes, Zaira Alexi Camacho‐Martinez, Deyanira Baca, Salvador Espino y Sosa, Raigam Jafet Martinez-Portilla, Lourdes Rojas‐Zepeda, Héctor Jesús Borboa-Olivares et al. · 2024 · International Journal of Molecular Sciences
A mini-review and perspective on ferroptosis-inducing strategies in cancer therapy
Shuaifei Wang, Hongwei Liao, Fangyuan Li, Daishun Ling · 2019 · Chinese Chemical Letters
Emerging roles of ferroptosis in liver pathophysiology
Kyu Min Kim, Sam Seok Cho, Sung Hwan Ki · 2020 · Archives of Pharmacal Research
Death by histone deacetylase inhibitor quisinostat in tongue squamous cell carcinoma via apoptosis, pyroptosis, and ferroptosis
Xinhuan Wang, Ke Liu, Huimin Gong, Dezhi Li, Wenfeng Chu, Dan Zhao, Xiaofeng Wang, Dongyang Xu · 2020 · Toxicology and Applied Pharmacology
Targetting ferroptosis for blood cell-related diseases
Zhe Chen, Jinyong Jiang, Nian Fu, Linxi Chen · 2021 · Journal of drug targeting
The Emerging Role of Ferroptosis in Liver Diseases
Si Chen, Junyao Zhu, Xin Zang, Yongzhen Zhai · 2021 · Frontiers in Cell and Developmental Biology
Activation of the P62‐Keap1‐NRF2 Pathway Protects against Ferroptosis in Radiation‐Induced Lung Injury
Xuan Li, Jingyao Chen, Sujuan Yuan, Xibing Zhuang, Tiankui Qiao · 2022 · Oxidative Medicine and Cellular Longevity
Porphyromonas gingivalis is a risk factor for the development of nonalcoholic fatty liver disease via ferroptosis
Chao Hua Yao, Dongmei Lan, Xue Li, Yan Wang, Shengcai Qi, Yuehua Liu · 2022 · Microbes and Infection
The mechanism of ferroptosis in early brain injury after subarachnoid hemorrhage
Xinpeng Deng, Yiwen Wu, Ziliang Hu, Shiyi Wang, Shengjun Zhou, Chenhui Zhou, Xiang Gao, Yi Huang · 2023 · Frontiers in Immunology
Autophagosomes Defeat Ferroptosis by Decreasing Generation and Increasing Discharge of Free Fe 2+ in Skin Repair Cells to Accelerate Diabetic Wound Healing
Shengnan Cui, Xi Liu, Yong Liu, Wenzhi Hu, Kui Ma, Qilin Huang, Ziqiang Chu, Lige Tian, Sheng Meng, Jianlong Su et al. · 2023 · Advanced Science
BNIP3-mediated mitophagy attenuates hypoxic–ischemic brain damage in neonatal rats by inhibiting ferroptosis through P62–KEAP1–NRF2 pathway activation to maintain iron and redox homeostasis
Xinxin Wang, Mei Li, Xiaowen Xu, Wenbin Zhao, Yi-ming Jin, Lili Li, Zheng-Hong Qin, Rui Sheng, Hong Ni · 2024 · Acta Pharmacologica Sinica
CRISPR/Cas9 genome-wide screening identifies KEAP1 as a sorafenib, lenvatinib, and regorafenib sensitivity gene in hepatocellular carcinoma
A. Zheng, Nadja Chevalier, Margot Calderoni, Gilles Dubuis, O. Dormond, Panos G. Ziros, G. Sykiotis, C. Widmann · 2019 · OncoTarget
Mechanisms of Modulation of Ferroptosis and Its Role in Central Nervous System Diseases
Qingyun Tan, Yuying Fang, Qiong Gu · 2021 · Frontiers in Pharmacology
Integrated Analysis of Immunity- and Ferroptosis-Related Biomarker Signatures to Improve the Prognosis Prediction of Hepatocellular Carcinoma
Xuanlong Du, Yewei Zhang · 2020 · Frontiers in Genetics
Ferroptosis as a new therapeutic opportunity for nonviral liver disease
Min Jia, Hongmei Zhang, Qiaohong Qin, Ying Hou, Xin Zhang, Di Chen, Hong Zhang, Yulong Chen · 2021 · European Journal of Pharmacology
GPX4‐Regulated Ferroptosis Mediates S100‐Induced Experimental Autoimmune Hepatitis Associated with the Nrf2/HO‐1 Signaling Pathway
Lujian Zhu, Da‐Zhi Chen, Yin Zhu, Tongtong Pan, Dingchao Xia, Tingchen Cai, Hongwei Lin, Jing Lin, Xiaozhi Jin, Fa-Ling Wu et al. · 2021 · Oxidative Medicine and Cellular Longevity
A Novel Insight Into the Fate of Cardiomyocytes in Ischemia-Reperfusion Injury: From Iron Metabolism to Ferroptosis
Jingyan Li, Shuangqing Liu, Ren-qi Yao, Yingping Tian, Yongming Yao · 2021 · Frontiers in Cell and Developmental Biology
PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
Qianping Zhang, Tiantian Sun, Yu Fan, Wei Liu, Jin Gao, Jinyu Chen, Hao Zheng, Jinming Liu, Chenjian Miao, Huanyi Guo et al. · 2024 · Nature Chemical Biology
PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
Xin Ping Yang, Zhe Wang, Светлана Николаевна Самович, Alexandr A. Kapralov, Andrew A. Amoscato, Vladimir A. Tyurin, Haider Hussain Dar, Zhiming Li, Shoufu Duan, Ning Kon et al. · 2024 · Cell Metabolism
The Tripartite Nexus: Autophagy, Cancer, and Tripartite Motif-Containing Protein Family Members
Michael A. Mandell, Bhaskar Saha, Todd A. Thompson · 2020 · Frontiers in Pharmacology
Effects of Lipid Peroxidation‐Mediated Ferroptosis on Severe Acute Pancreatitis‐Induced Intestinal Barrier Injury and Bacterial Translocation
Deliang Ma, Pengling Jiang, Yingjian Jiang, Hongbo Li, Dianliang Zhang · 2021 · Oxidative Medicine and Cellular Longevity
Designer Exosomes for Targeted Delivery of a Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma
Xiaoju Li, Qianqian Yu, Runze Zhao, Xinyan Guo, Chenlin Liu, Kuo Zhang, Wangqian Zhang, Jinghan Liu, Jinzheng Yu, Shuning Wang et al. · 2022 · Frontiers in Oncology
Free docosahexaenoic acid promotes ferroptotic cell death via lipoxygenase dependent and independent pathways in cancer cells
Kai Shan, Ninghan Feng, Doudou Zhu, Hongyan Qu, Guoling Fu, Jiaqi Li, Jing Cui, Heyan Chen, Rong Wang, Yumin Qi et al. · 2022 · European Journal of Nutrition
Ferroptosis: a new hunter of hepatocellular carcinoma
Yulang Jiang, Yongxin Yu, Ziyang Pan, Christian Glandorff, Mingyu Sun · 2024 · Cell Death Discovery
Protein modification and degradation in ferroptosis
Yuan Wang, Yan Ding, Jinbao Liu, Daolin Tang, Xin Chen · 2024 · Redox Biology
Shuganning injection, a traditional Chinese patent medicine, induces ferroptosis and suppresses tumor growth in triple-negative breast cancer cells
Jingjing Du, Lishuang Wang, Xiaoming Huang, Na Zhang, Ze Long, You Qing Yang, Fangfang Zhong, Bowen Zheng, Wen‐Jian Lan, Wanjun Lin et al. · 2021 · Phytomedicine
Implications of Withaferin A for the metastatic potential and drug resistance in hepatocellular carcinoma cells via Nrf2-mediated EMT and ferroptosis
Yigang Zhang, Yi Tan, Shuangchi Liu, Hongxiang Yin, Jiakang Duan, Longfei Fan, Xiangyang Zhao, Bowen Jiang · 2022 · Toxicology Mechanisms and Methods
Combination of Metformin and Sorafenib Induces Ferroptosis of Hepatocellular Carcinoma Through p62-Keap1-Nrf2 Pathway
Kezhong Tang, Qing Chen, Yanmo Liu, Lantian Wang, Wenjie Lu · 2022 · Journal of Cancer
Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells
Zeyu Wang, Weijian Li, Xue Wang, Qin Zhu, Liguo Liu, Shimei Qiu, Lu Zou, Ke Liu, Guoqiang Li, Huijie Miao et al. · 2023 · Chinese Medical Journal
Ferroptosis and Its Modulation by Autophagy in Light of the Pathogenesis of Lysosomal Storage Diseases
Karolina Pierzynowska, Estera Rintz, Lidia Gaffke, Grzegorz Węgrzyn · 2021 · Cells
Shedding a New Light on Skin Aging, Iron- and Redox-Homeostasis and Emerging Natural Antioxidants
Charareh Pourzand, A. Albieri, Nico N. Raczek · 2022 · Antioxidants
d-Borneol enhances cisplatin sensitivity via autophagy dependent EMT signaling and NCOA4-mediated ferritinophagy
Jinxiu Li, Jianmei Yuan, Yong Li, Jian Wang, Qian Xie, Rong Ma, Jiajun Wang, Mihong Ren, Danni Lu, Zhuo Xu · 2022 · Phytomedicine
Interplay of Ferroptosis and Cuproptosis in Cancer: Dissecting Metal-Driven Mechanisms for Therapeutic Potentials
Jinjiang Wang, Jiaxi Li, Jiao Liu, Kit-Ying Chan, Jacqueline Ho Sze Lee, Kenneth Nansheng Lin, Chi Chiu Wang, Tat‐San Lau · 2024 · Cancers
Advances in research on immunocyte iron metabolism, ferroptosis, and their regulatory roles in autoimmune and autoinflammatory diseases
Liuting Zeng, Kailin Yang, Ganpeng Yu, Wensa Hao, Xiaofei Zhu, Anqi Ge, Junpeng Chen, Lingyun Sun · 2024 · Cell Death and Disease
Risk factors for hepatocellular carcinoma: an umbrella review of systematic review and meta-analysis
Jie Wang, Kaijie Qiu, Songsheng Zhou, Yichao Gan, Keting Jiang, Donghuan Wang, Haibiao Wang · 2025 · Annals of Medicine
A Novel Ferroptosis-Associated Gene Signature to Predict Prognosis in Patients with Uveal Melanoma
Huan Luo, Chao Ma · 2021 · Diagnostics
Environmental allergens house dust mite‑induced asthma is associated with ferroptosis in the lungs
Weifeng Tang, Ming Dong, Fangzhou Teng, Jie Cui, Xueyi Zhu, Wenqian Wang, Tulake Wuniqiemu, Jingjing Qin, La Yi, Shiyuan Wang et al. · 2021 · Experimental and Therapeutic Medicine
Tumour cells are sensitised to ferroptosis via RB1CC1‐mediated transcriptional reprogramming
Xiangfei Xue, Lifang Ma, Xiao Zhang, Xin Xu, Susu Guo, Yikun Wang, Shiyu Qiu, Jiangtao Cui, Wanxin Guo, Yongchun Yu et al. · 2022 · Clinical and Translational Medicine
Ferroptosis in Hepatocellular Carcinoma: Mechanisms, Drug Targets and Approaches to Clinical Translation
Dino Bekric, Matthias Ocker, Christian Mayr, Sebastian Stintzing, Markus Ritter, Tobias Kiesslich, Daniel Neureiter · 2022 · Cancers
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma
Yating Liu, Lianlian Ouyang, Chao Mao, Yuanbing Chen, Tiansheng Li, Na Liu, Zuli Wang, Weiwei Lai, Yanling Zhou, Ya Cao et al. · 2022 · Oncogene
Ferroptosis contribute to hepatic stellate cell activation and liver fibrogenesis
Sam Seok Cho, Ji Hye Yang, Ji‐Hyun Lee, Jin Sol Baek, Sae‐Kwang Ku, Il Je Cho, Kyu Min Kim, Sung Hwan Ki · 2022 · Free Radical Biology and Medicine
Ferroptosis: The Entanglement between Traditional Drugs and Nanodrugs in Tumor Therapy
Kexuan Liu, Lei Huang, Shuangyan Qi, Shuchen Liu, Wangni Xie, Liuyi Du, Cui Jing, Xu Zhang, Boya Zhang, Lijun Liu et al. · 2023 · Advanced Healthcare Materials
Lycium barbarum polysaccharide-glycoprotein ameliorates ionizing radiation-induced epithelial injury by regulating oxidative stress and ferroptosis via the Nrf2 pathway
Sijing Jiang, Xun Xiao, Jing Li, Yandong Mu · 2023 · Free Radical Biology and Medicine
Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants
Xiao‐Yuan Mao, Ming-Zhu Jin, Jinfei Chen, Hong‐Hao Zhou, Weilin Jin · 2017 · Pharmacology & Therapeutics
Redox Modulation and Induction of Ferroptosis as a New Therapeutic Strategy in Hepatocellular Carcinoma
Jana Lippmann, Kathrin Petri, Simone Fulda, Juliane Liese · 2020 · Translational Oncology
MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1G93A Motor Neuron of Amyotrophic Lateral Sclerosis
Jialing Peng, Jingrui Pan, Jingjing Mo, Ying Peng · 2022 · Oxidative Medicine and Cellular Longevity
Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis
Feng, Lifeng, Chen, Miaoqin, Li, Yiling, Li, Muchun, Hu, Shiman, Zhou, Bingluo, Zhu, Liyuan, Yu, Lei, Zhou, Qiyin, Tan, Linghui et al. · 2021 · Cell Death & Disease
Mitochondria autophagy: a potential target for cancer therapy
Yu-Han Qiu, Tianshu Zhang, Xiaowei Wang, Meng‐Yan Wang, Wenxia Zhao, Huimin Zhou, Cong-Hui Zhang, Meilian Cai, Xiaofang Chen, Wuli Zhao et al. · 2021 · Journal of drug targeting
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice
Ping Han, Xia Wang, Tianqiu Zhou, Jinmei Cheng, Chengniu Wang, Fei Sun, Xi Zhao · 2022 · Free Radical Biology and Medicine
Ferroptosis in tumor immunity and therapy
Chuandong Gong, Qiankun Ji, Miaojing Wu, Zewei Tu, Kunjian Lei, Min Luo, Junzhe Liu, Li Lin, Kuangxun Li, Jingying Li et al. · 2022 · Journal of Cellular and Molecular Medicine
Targeting lipid metabolism for ferroptotic cancer therapy
Minhua Luo, Jiajing Yan, Xinyu Hu, Haolong Li, Hongsheng Li, Quentin Liu, Yibing Chen, Zhengzhi Zou · 2022 · APOPTOSIS
RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems
Daiha Shin, Eun Hye Kim, Jaewang Lee, Jong‐Lyel Roh · 2017 · Redox Biology
Oxaliplatin induces ferroptosis and oxidative stress in HT29 colorectal cancer cells by inhibiting the Nrf2 signaling pathway
Liu, Ben, Wang, Hui · 2022 · Experimental and Therapeutic Medicine
Metal ions/nucleotide coordinated nanoparticles comprehensively suppress tumor by synergizing ferroptosis with energy metabolism interference
Yanqiu Wang, Jie Chen, Jianxiu Lu, Juqun Xi, Zhilong Xu, Lei Fan, Hua Dai, Lizeng Gao · 2022 · Journal of Nanobiotechnology
Relationship between miRNA and ferroptosis in tumors
Shang‐Ming Dai, Feng‐Jiao Li, Hui‐Zhi Long, Zi-Wei Zhou, Hongyu Luo, Shuo‐Guo Xu, Lichen Gao · 2022 · Frontiers in Pharmacology
Ferroptosis and Neurodegenerative Diseases: Insights into the Regulatory Roles of SLC7A11
Chen Wang, Haihui Liu, Si Xu, Yu Lin Deng, Bin Xu, Tianyao Yang, Wei Liu · 2023 · Cellular and Molecular Neurobiology
Type 2 diabetic mellitus related osteoporosis: focusing on ferroptosis
Yili Chen, Wen Zhao, An Hu, Shi Lin, Ping Chen, Bing Yang, Zhirong Fan, Ji Qi, Wenhui Zhang, Huanhuan Gao et al. · 2024 · Journal of Translational Medicine
Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury
Kuo Du, Seh‐Hoon Oh, Rajesh Kumar Dutta, Tianai Sun, Wen‐Hsuan Yang, Jen‐Tsan Chi, Anna Mae Diehl · 2021 · Liver International
Development and Validation of a Random Forest Diagnostic Model of Acute Myocardial Infarction Based on Ferroptosis-Related Genes in Circulating Endothelial Cells
Chen Yifan, Shi Jianfeng, Jun Pu · 2021 · Frontiers in Cardiovascular Medicine
Mechanisms and pharmacological applications of ferroptosis: a narrative review
Jingjing Zhang, Jing Du, Ni Kong, Guangyu Zhang, Mengzhen Liu, Chong Liu · 2021 · Annals of Translational Medicine
Lycopene alleviates di(2-ethylhexyl) phthalate-induced splenic injury by activating P62-Keap1-NRF2 signaling
Xueyan Dai, Shi‐Yong Zhu, Jian Chen, Muzi Li, Yi Peng Zhao, Milton Talukder, Jin‐Long Li · 2022 · Food and Chemical Toxicology
Cycloacceleration of Reactive Oxygen Species Generation Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for Tumor Ferroptosis Therapy
Huimin Zhou, Xuanyi Lu, Chao Du, Zijian Zhou, Jie Feng, Zhiyu Liang, Yikai Xu, Xiaozhong Qiu, Zheyu Shen · 2022 · Small