Hepatic fibrosis 2022: Unmet needs and a blueprint for the future

Friedman, Scott L., Pinzani, Massimo·2022·Hepatology

DOI 10.1002/hep.32285

Cited by (432)

Items 301–400 of 432

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Acetoacetate Ameliorates Hepatic Fibrosis by Targeting Peroxisome Proliferator-Activated Receptor Gamma to Restore Lipid Droplets in Activated Hepatic Stellate Cells
Ya Zhou, Feixia Wang, Mengru Hu, Siwei Xia, Li Yang, Shizhong Zheng, Feng Zhang · 2025 · Pharmaceuticals
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X F Zhuang, YuanBin He, Dianming Wu, Yifan Fang, Yu‐Hsuan Lin, Yan-Bing Huang · 2025 · Frontiers in Pediatrics
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Jiaxin Xia, Xiao Ping Tang, Qihua Zhu, Yizhu Xu · 2025 · npj gut and liver.
Serum asprosin level is significantly lower in patients with liver cirrhosis than in those with non-cirrhotic chronic liver diseases
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RAB25 promotes hepatitis B virus-induced liver fibrosis progression through activation of the PI3K/AKT signaling pathway
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Mahboubeh Varmazyad, Dillon C. Gavlock, Michael W. Castiglione, Richard DeBiasio, Gregory M LaRocca, Celeste E. Reese, Lawrence A. Vernetti, Mark E. Schurdak, Andrew M. Stern, D. Lansing Taylor et al. · 2026 · BMC Methods
Asarinin alleviates hepatic fibrosis through TRα-STAT3 pathway: A new strategy by regulating liver microenvironment
Jiaqi Yang, Shu-Ya Li, Peng Jiang, Guo-Li Wu, Zheng Luo, Xin Guo, Xue-Kun Liu, Haiming Sun, Yu-Chen Jiang · 2026 · Journal of Ethnopharmacology
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Long Hao Xu, Runyan He, Yan Neng Kang, Heng Hong Lin, Jia En Yang, Hua Xiao Chen, Xue Ting Huang, Xiao Lu Wu, Baohui Pei, Chao Zhou et al. · 2026 · PeerJ
Rougan Granules ameliorates liver fibrosis through autophagy regulation: Insights from HPLC-Q-TOF-MS/MS, network pharmacology, and experimental validation
Meng-Chao Wen, Ji-Yue Li, QianQian Sun, Chen Hu, SuLan Ju, Fang Tian, Biqing Chen, Chenyao Li, YanMei Liu, Jin‐Yong Zhou et al. · 2026 · Journal of Chromatography B
6-Shogaol inhibits HSCs activation and liver fibrosis by regulating glycolytic reprogramming via targeting HIF-1α
Jie Yang, M Z Shu, Hui Fang, F Y Yang, J R Li, Yuansong Sun, H H Li, Tao Xu · 2026 · Chinese Medicine
Role of the gut microbiota–bile acid axis in liver fibrosis based on microbiomics and targeted metabolomics
Yu-Lin Zhang, Hong-Zhong Gou, Zhen-Jiao Li, Jia-Hui Xi, Xiao-Juan Wang, Jin Shang, Dan Zhu, Longfei Ren, Xiao-Jun Shu, Lei Zhang (38117) · 2026 · BMC Microbiology
Huaganjian decoction attenuates liver fibrosis via purine metabolic-inflammatory synergistic crosstalk: network pharmacology combined with multi-omics analyses
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α-Ketoglutarate mitigates titanium dioxide nanoparticle-induced hepatotoxicity by reinforcing redox balance and PI3K-Akt activation
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Oleic acid modulates perilipin expression and lipid droplet contents in TGFβ1 activated HSCs
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Fibrosis regression in chronic liver disease: The pathologist’s view
Alastair D. Burt, Cynthia Behling, Annette S.H. Gouw, Prodromos Hytiroglou, Carolin Lackner, Venâncio Avancini Ferreira Alves, Valérie Paradis, Young Nyun Park, Peter Schirmacher, DINA G. TINIAKOS · 2026 · Journal of Hepatology
Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancer
Clemens Hinterleitner, Valentin J.A. Barthet, Hailey V. Goldberg, Kristen C. Vogt, Ana Marie Perea, Logan R. Hillger, Stephen B. Ruiz, Domhnall McHugh, Yu-Jui Ho, Almudena Chaves Perez et al. · 2026 · Science
Perfil de un judeoconverso del Reino de Granada: el escribano Antón López de Toledo
M. T. Beltrán · 2006 · Revista del Centro de Estudios Históricos de Granada y su Reino/Revista del Centro de Estudios Históricos de Granada y su Reino
Collagens of the third and fourth types in various forms of alcoholic liver disease
Ольга Петровна Дуданова, Алиса Сергеевна Родина, Марина Эдуардовна Шубина, Курбатова Ирина Валерьевна, Ludmila V. Topchieva · 2023 · Экспериментальная и клиническая гастроэнтерология
In situ subtotal spleen resection combined with selective pericardial devascularization for the treatment of portal hypertension
Hailin Li, Shanglei Ning, Yanjing Gao, Tao Zhou, Yuxin Chen · 2023 · World Journal of Gastrointestinal Surgery
Farnesoid X receptor modulator 12β-( m -methyl-benzoyl)-11,12-dihydro oleanolic acid represses liver fibrosis by inhibiting ERK/p38 signaling pathways
Yiming Li, Yunyang Bao, Simin Guo, Yang Li, Wei‐Shuo Fang, Na Zhang, Hongwei He · 2024 · Toxicology Mechanisms and Methods
Analysis of the relationship between Cxcl12, Tweak, Notch1 and Yap1 mRNA expression in the molecular mechanisms of liver fibrogenesis
E. I. Lebedeva, Anatoliy T. Shchastniy, Andrei S. Babenka, Dmitry Aleksandrovich Zinovkin · 2024 · Molecular Biology
Second harmonic generation digital pathology with artificial intelligence: breakthroughs in studying fibrosis dynamics and treatment response
Nikolai V. Naoumov, Elaine Chng · 2024 · Future Medicine AI
Cpd861 Targeting BCL2 to Alleviate Hepatic Fibrosis: Network Pharmacology, Mendelian Randomization, and Molecular Docking Mechanisms
Yaning Lyu, Xifeng Liang, Shuang Gao, Jing Li, Jinming Li, Shuhan Zhang, Chenghong Yin, Cheng Chi · 2024 · Current Pharmaceutical Design
A Novel Nanoscale Phase-Change Contrast Agent Evaluates the Hepatic Fibrosis Through Targeting Hepatic Stellate Cell Platelet-Derived Factor Beta Receptor by Ultrasound in Vitro
Hanmei Li, Linli Feng, Qiong Jiang, You Yang, Juying Zhang, Xia Luo, Xing Yang, Bo Ren, Li-tao Ye, Zheng-ju Hou et al. · 2024 · Ultrasound in Medicine & Biology
Engineered Intelligent Microenvironment Responsive Prodrug Conjugates Navigated by Bioinspired Lipoproteins for Reversing Liver Fibrosis
Mingzhu Fang, Boyu Su, Shilin Zhang, Fangxin Li, Yun Guo, Qinjun Chen, Yuxing Wu, Huiyi Liu, Chen Jiang, Tao Sun · 2025 · Small Methods
Correlation of liver fibrosis quantification by morphometry using HepaScan with the analysis of liver biopsies. A pilot study
Nathalie Alemán-García, José Antonio García-García, Marco A. Durán-Padilla, María E. Gutiérrez-Díaz-de Ceballos, Thelma Rizo-Pica, Ana del Carmen Susunaga Notario, Celia A. Sanchez-Perez · 2023 · Gaceta Médica de México
Special Issue on “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis II”
Ralf Weiskirchen · 2022 · Cells
Persistence of fibrogenic process in direct-acting antiviral (DAA) treated patients?
Cecilia Battistelli, Marco Tripodi · 2022 · ExRNA
Non-Alcoholic Steatohepatitis (NASH) and Liver Fibrosis: Molecular and Multicellular Control of Evolving Diseased States
Jérôme Eeckhoute · 2022 · Cells
Role of Sonoelastography in Evaluation of Liver Fibrosis: Review Article
Omar Ahmed Abdellatif Ahmed · 2022 · The Egyptian Journal of Hospital Medicine
Study on the Mechanism of Blood Circulation in Patients with Liver Fibrosis
莉田 · 2022 · Advances in Clinical Medicine
Deep Learning Based Classiftcation of Normal and Hepatic Fibrosis Mouse Model Using Digital Pathology Images
Ayesha Kousar, Shivam Damani, Priyanka Anvekar, Arush Rajotia, Keerthy Gopalakrishnan, Bhavana Baraskar, Vaishnavi Kalpesh Modi, Keirthana Aedma, Joshika Agarwal, Hima Varsha Voruganti et al. · 2022 · IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Correlación de la cuantificación de fibrosis hepática por morfometría mediante HepaScan con el análisis de las biopsias hepáticas. Estudio piloto
Nathalie Alemán-García, José Antonio García-García, Marco A. Durán-Padilla, María E. Gutiérrez-Díaz-de Ceballos, Thelma Rizo-Pica, Ana del Carmen Susunaga Notario, Celia A. Sanchez-Perez · 2023 · Gaceta Médica de México
Book Review: Weiskirchen, R.; Friedman, S.L. Hepatic Stellate Cells: Methods and Protocols, 1st Ed.; Weiskirchen, R., Friedman, S.L., Eds.; Methods in Molecular Biology 2669; Humana Press: New York, NY, USA, 2023; ISBN 978-1-07-163206-2; eISBN: 978-1-0716-3207-9
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Shuya Zhang, Ying Liu, Liping Chen, Yuxuan Liu, Yuqi Guo, Jilin Cheng, Jun Huang · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Special Issue “Liver Fibrosis: Mechanisms, Targets, Assessment and Treatment”
Ralf Weiskirchen, Tilman Sauerbruch · 2023 · Livers
Effect of mycophenolate mofetil alleviates carbon tetrachloride-induced liver fibrosis in mice.
Peng Ding, Pengpeng Zhang, Hao Li, Yingzi Ming · 2023 · PubMed Central
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Manon Allaire, Charles Roux, Sepideh Akhavan, Pascal Lebray, Dominique Thabut · 2023 · Clinics and Research in Hepatology and Gastroenterology
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Kaitlyn Hinz, Wen‐Xing Ding · 2023 · Cellular and Molecular Gastroenterology and Hepatology
Alcoholic Fibrosis/Cirrhosis and Its Reversibility
Massimo Pinzani · 2023 · Springer eBooks
Wuling Capsule Modulates Macrophage Polarization by Inhibiting the TLR4-NF-κB Signaling Pathway to Relieve Liver Fibrosis
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Additional file 2 of Cyp4a12-mediated retinol metabolism in stellate cells is the antihepatic fibrosis mechanism of the Chinese medicine Fuzheng Huayu recipe
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Pathological and Ultrastructural Study on the Chronic Liver Damage Induced by Thioacetamide in Male Rats.
Sohaila Abd El-Hameed, Iman Ibrahim, Walaa Fekri Awadin, Ahmed El-Shaieb · 2024 · Egyptian Journal of Veterinary Science
Dietary Nutritional Supplements Are Associated with the Deterioration of Hepatic Fibrosis in Women and Individuals without Underlying Disease
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R-Spondin Mimetic, SZN-043, Induced Proliferation and Expression of Wnt Target Genes, Two Impaired Features in Human Alcohol-Associated Liver Disease
Trevor Fisher, Mehaben Patel, Shalaka Deshmukh, Darshini Shah, Chenggang Lu, Maureen R. Newman, Jay Ye, Russell B. Fletcher, Geertrui F. Vanhove, Jay Tibbitts et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
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R-Spondin Mimetic, SZN-043, Induced Proliferation and Expression of Wnt Target Genes, Two Impaired Features in Human Alcohol-Associated Liver Disease
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R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease
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Additional file 1 of Cyp4a12-mediated retinol metabolism in stellate cells is the antihepatic fibrosis mechanism of the Chinese medicine Fuzheng Huayu recipe
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Additional file 1 of lncRNA Helf promotes hepatic inflammation and fibrosis by interacting with PTBP1 to facilitate PIK3R5 mRNA stabilization
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Additional file 1 of Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis
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Additional file 2 of Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis
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Additional file 2 of lncRNA Helf promotes hepatic inflammation and fibrosis by interacting with PTBP1 to facilitate PIK3R5 mRNA stabilization
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