Friedman, Scott L.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Mechanisms of NAFLD development and therapeutic strategies

Friedman, S. L., Neuschwander-Tetri, B. A., Rinella, M., & Sanyal, A. J. (2018) · Nature Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 4,354

Mechanisms of hepatic stellate cell activation

Tsuchida, T., & Friedman, S. L. (2017) · Nature Reviews Gastroenterology & Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 2,909

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

Friedman, S. L. (2008) · Physiological Reviews

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 2,842

Weight loss through lifestyle modification significantly reduces features of nonalcoholic steatohepatitis

Vilar-Gomez, E., Martinez-Perez, Y., Calzadilla-Bertot, L., Torres-Gonzalez, A., Gra-Oramas, B., Gonzalez-Fabian, L., Friedman, S. L., Diago, M., & Romero-Gomez, M. (2015) · Gastroenterology

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 2,492

Mechanisms and disease consequences of nonalcoholic fatty liver disease

Loomba, R., Friedman, S. L., & Shulman, G. I. (2021) · Cell

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 2,002

Pathogenesis of Liver Fibrosis

Hernandez-Gea, V., & Friedman, S. L. (2011) · Annual Review of Pathology: Mechanisms of Disease

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 1,809

Liver fibrosis – from bench to bedside

Friedman, S. L. (2003) · Journal of Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 1,780

Hepatic stellate cells as key target in liver fibrosis

Higashi, T., Friedman, S. L., & Hoshida, Y. (2017) · Advanced Drug Delivery Reviews

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 1,485

Gene expression in fixed tissues and outcome in hepatocellular carcinoma

Hoshida, Y., Villanueva, A., Kobayashi, M., Peix, J., Chiang, D. Y., Camargo, A., Gupta, S., Moore, J., Wrobel, M. J., Lerner, J., et al. (2008) · New England Journal of Medicine

Gene expression and cancer classificationHepatocellular Carcinoma Treatment and Prognosis

Cited by 1,286

Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma

Hoshida, Y., Nijman, S. M. B., Kobayashi, M., Chan, J. A., Brunet, J.-P., Chiang, D. Y., Villanueva, A., Newell, P., Ikeda, K., Hashimoto, M., et al. (2009) · Cancer Research

Hepatocellular Carcinoma Treatment and PrognosisGene expression and cancer classification

Cited by 1,238

Senolytic CAR T cells reverse senescence-associated pathologies

Amor, C., Feucht, J., Leibold, J., Ho, Y.-J., Zhu, C., Alonso-Curbelo, D., Mansilla-Soto, J., Boyer, J. A., Li, X., Giavridis, T., et al. (2020) · Nature

Telomeres, Telomerase, and SenescenceCAR-T cell therapy research

Cited by 1,098

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features

Sia, D., Jiao, Y., Martinez-Quetglas, I., Kuchuk, O., Villacorta-Martin, C., Castro de Moura, M., Putra, J., Camprecios, G., Bassaganyas, L., Akers, N., et al. (2017) · Gastroenterology

Cancer Immunotherapy and BiomarkersHepatocellular Carcinoma Treatment and Prognosis

Cited by 976

Mechanisms of hepatic fibrogenesis

Lee, U. E., & Friedman, S. L. (2011) · Best Practice & Research Clinical Gastroenterology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 923

p53 Activates the CD95 (APO-1/Fas) Gene in Response to DNA Damage by Anticancer Drugs

Müller, M., Wilder, S., Bannasch, D., Israeli, D., Lehlbach, K., Li-Weber, M., Friedman, S. L., Galle, P. R., Stremmel, W., Oren, M., et al. (1998) · The Journal of Experimental Medicine

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 878

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.

Friedman, S. L., Roll, F. J., Boyles, J., & Bissell, D. M. (1985) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 859

Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

Chiang, D. Y., Villanueva, A., Hoshida, Y., Peix, J., Newell, P., Minguez, B., LeBlanc, A. C., Donovan, D. J., Thung, S. N., Solé, M., et al. (2008) · Cancer Research

Hepatocellular Carcinoma Treatment and PrognosisCancer Genomics and Diagnostics

Cited by 719

Hepatic fibrosis: concept to treatment

Trautwein, C., Friedman, S. L., Schuppan, D., & Pinzani, M. (2015) · Journal of Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 677

A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis

Friedman, S. L., Ratziu, V., Harrison, S. A., Abdelmalek, M. F., Aithal, G. P., Caballeria, J., Francque, S., Farrell, G., Kowdley, K. V., Craxi, A., et al. (2018) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 671

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

Fujiwara, N., Friedman, S. L., Goossens, N., & Hoshida, Y. (2018) · Journal of Hepatology

Hepatocellular Carcinoma Treatment and PrognosisHepatitis B Virus Studies

Cited by 659

Therapy for Fibrotic Diseases: Nearing the Starting Line

Friedman, S. L., Sheppard, D., Duffield, J. S., & Violette, S. (2013) · Science Translational Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisLiver physiology and pathology

Cited by 655

Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues

Hernández–Gea, V., Ghiassi–Nejad, Z., Rozenfeld, R., Gordon, R., Fiel, M. I., Yue, Z., Czaja, M. J., & Friedman, S. L. (2012) · Gastroenterology

Liver physiology and pathologyAutophagy in Disease and Therapy

Cited by 654

A simple diet- and chemical-induced murine NASH model with rapid progression of steatohepatitis, fibrosis and liver cancer

Tsuchida, T., Lee, Y. A., Fujiwara, N., Ybanez, M., Allen, B., Martins, S., Fiel, M. I., Goossens, N., Chou, H.-I., Hoshida, Y., et al. (2018) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 583