The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Establishment of a continuous tumor‐cell line (PANC‐1) from a human carcinoma of the exocrine pancreas
Abstract
An epithelioid cell line, started from a human pancreatic carcinoma of ductal cell origin, has been maintained in culture for over 2 years and has been subcultured more than 40 times. The PANC‐1 cell line has a doubling time of 52 h and G6PD activity of the slow mobility or B type. Chromosome studies show a modal number of 63 with three distinct marker chromosomes and a small ring chromosome. The malignant nature of the PANC‐1 cell line was verified by: (1) the ready growth of PANC‐1 cells in soft agar and on top of a fibroblast monolayer; and (2) the formation of a progressively growing anaplastic carcinoma after injection of a nude‐athymic mouse with PANC‐1 cells.
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Citations
Cites
Banded Marker Chromosomes as Indicators of Intraspecies Cellular Contamination
Nelson-Rees, W. A., Flandermeyer, R. R., & Hawthorne, P. K. (1974) · Science · doi:10.1126/science.184.4141.1093 · Cited by 210
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Cited by
Phenotype and Genotype of Pancreatic Cancer Cell Lines
Deer, E. L., González-Hernández, J., Coursen, J. D., Shea, J. E., Ngatia, J., Scaife, C. L., Firpo, M. A., & Mulvihill, S. J. (2010) · Pancreas · doi:10.1097/mpa.0b013e3181c15963 · Cited by 936
Human pancreatic carcinoma (mia paca‐2) in continuous culture: Sensitivity to asparaginase
Yunis, A. A., Arimura, G. K., & Russin, D. J. (1977) · International Journal of Cancer · doi:10.1002/ijc.2910190118 · Cited by 373
Genetic profile of 22 pancreatic carcinoma cell lines: Analysis of K-ras, p53, p16 and DPC4/Smad4
Moore, P. S., Sipos, B., Orlandini, S., Sorio, C., Real, F. X., Lemoine, N. R., Gress, T., Bassi, C., Klöppel, G., Kalthoff, H., et al. (2001) · Virchows Archiv · doi:10.1007/s004280100474 · Cited by 329
Lazzari, G., Nicolas, V., Matsusaki, M., Akashi, M., Couvreur, P., & Mura, S. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.08.008 · Cited by 271
Divergent Roles for RalA and RalB in Malignant Growth of Human Pancreatic Carcinoma Cells
Lim, K.-H., O'Hayer, K., Adam, S. J., Kendall, S. D., Campbell, P. M., Der, C. J., & Counter, C. M. (2006) · Current Biology · doi:10.1016/j.cub.2006.10.023 · Cited by 250
Metadata
- Authors
- Lieber, M., Mazzetta, J., Nelson‐Rees, W., Kaplan, M., & Todaro, G.
- Venue
- International Journal of Cancer
- Publisher
- Wiley
- Published
- 1975-05-15
- Volume
- 15
- Issue
- 5
- Pages
- 741-747
- ISSN
- 0020-7136 (ISSN-L)
- 1097-0215
- OpenAlex
- W2132235170
- Cited by
- 508
- References
- 1
- FWCI
- 1.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lieber, M., Mazzetta, J., Nelson‐Rees, W., Kaplan, M., & Todaro, G. (1975). Establishment of a continuous tumor‐cell line (PANC‐1) from a human carcinoma of the exocrine pancreas. International Journal of Cancer. https://doi.org/10.1002/ijc.2910150505
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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