The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Detection of antibodies against the cellular protein p53 in sera from patients with breast cancer
Abstract
Antibodies reacting with the host protein p53 were found in the sera of patients with primary or secondary carcinoma of the breast. Fourteen out of the 155 sera from breast cancer patients tested were positive for anti‐p53 antibodies (9%) and no positives were detected among 164 control sera from normal women tested. The locations of the first metastasis in patients with positive sera were unusual, with more lung metastases and fewer bone metastases than expected. The detection of anti‐p53 antibodies indicates that p53 is altered in amount, type or presentation in breast tumors so that it becomes immunogenic.
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Cites
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Self-citationMonoclonal antibodies specific for simian virus 40 tumor antigens
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A monoclonal antibody that recognizes B cells and B cell precursors in mice.
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Detection of a common feature in several human tumor cell lines--a 53,000-dalton protein.
Crawford, L. V., Pim, D. C., Gurney, E. G., Goodfellow, P., & Taylor-Papadimitriou, J. (1981) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.78.1.41 · Cited by 236
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Cited by
Kastenhuber, E. R., & Lowe, S. W. (2017) · Cell · doi:10.1016/j.cell.2017.08.028 · Cited by 1,906
Weinberg, R. A. (1991) · Science · doi:10.1126/science.1659741 · Cited by 1,756
Rivlin, N., Brosh, R., Oren, M., & Rotter, V. (2011) · Genes & Cancer · doi:10.1177/1947601911408889 · Cited by 1,033
p53 and Human Cancer: The First Ten Thousand Mutations
(1999) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60785-x · Cited by 986
P53 expression in breast cancer
Cattoretti, G., Rilke, F., Andreola, S., D'Amato, L., & Delia, D. (1988) · International Journal of Cancer · doi:10.1002/ijc.2910410204 · Cited by 601
Metadata
- Authors
- Crawford, L. V., Pim, D. C., & Bulbrook, R. D.
- Venue
- International Journal of Cancer
- Publisher
- Wiley
- Published
- 1982-10-15
- Volume
- 30
- Issue
- 4
- Pages
- 403-408
- ISSN
- 0020-7136 (ISSN-L)
- 1097-0215
- OpenAlex
- W2075847417
- Cited by
- 450
- References
- 12
- FWCI
- 2.67
- Type
- journal article
- Language
- en
- Open access
- closed
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- Crawford, L. V., Pim, D. C., & Bulbrook, R. D. (1982). Detection of antibodies against the cellular protein p53 in sera from patients with breast cancer. International Journal of Cancer. https://doi.org/10.1002/ijc.2910300404
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
