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Cited by 439

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Human papillomavirus type‐16‐related DNA in genital Bowen's disease and in bowenoid papulosis

Ikenberg, Hans, Gissmann, Lutz, Gross, Gerd, Grussendorf‐Conen, Elke‐Ingrid, Hausen, Harald Zur·1983·International Journal of Cancer

Abstract

32 P‐labelled DNA of HPV 16 which has been isolated and molecularly cloned from a cervical carcinoma (Dürst et al., 1983) was used to screen the cellular DNAs obtained from 20 different biopsies of Morbus Bowen or Bowenoid papulosis, respectively, by Southern blot analysis. Under conditions of differing stringency for the hybridization, HPV 16 DNA or related sequences were identified in 6 out of 10 cases of Morbus Bowen (4 out of 5 from a genital localization) and in 8 out of 10 biopsies from Bowenoid papulosis. One additional case of the latter disease contained DNA sequences of an HPV type not yet classified. There is evidence for the presence of another HPV DNA in two of the HPV‐16‐positive tumors. A large number of normal genital tissue samples were negative for HPV DNA.

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Metadata

Authors
Ikenberg, H., Gissmann, L., Gross, G., Grussendorf‐Conen, E., & Hausen, H. Z.
Venue
International Journal of Cancer
Publisher
Wiley
Published
1983-11-15
Volume
32
Issue
5
Pages
563-565
ISSN
  • 0020-7136 (ISSN-L)
  • 1097-0215
OpenAlex
W2039288030
Cited by
439
References
0
FWCI
23.68
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Human papillomavirus type‐16‐related DNA in genital Bowen's disease and in bowenoid papulosis. https://app.cochat.ai/papers/10.1002/ijc.2910320507
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Ikenberg, H., Gissmann, L., Gross, G., Grussendorf‐Conen, E., & Hausen, H. Z. (1983). Human papillomavirus type‐16‐related DNA in genital Bowen's disease and in bowenoid papulosis. International Journal of Cancer. https://doi.org/10.1002/ijc.2910320507

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