Nonoxidative ethanol metabolism in humans—from biomarkers to bioactive lipids

The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification

Rowland, A., Miners, J. O., & Mackenzie, P. I. (2013) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2013.02.019 · Cited by 712 · see citing works

Presence of Nonoxidative Ethanol Metabolism in Human Organs Commonly Damaged by Ethanol Abuse

Laposata, E. A., & Lange, L. G. (1986) · Science · doi:10.1126/science.3941913 · Cited by 493 · see citing works

Chronic diseases and conditions related to alcohol use

Shield, K. (2013) · Alcohol Research: Current Reviews · doi:10.35946/arcr.v35.2.06 · Cited by 488 · cited 1× · see citing works

Phosphatidylethanol Formation via Transphosphatidylation by Rat Brain Synaptosomal Phospholipase D

Kobayashi, M., & Kanfer, J. N. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb05707.x · Cited by 344 · see citing works

Fatty Acid Ethyl Esters Cause Pancreatic Calcium Toxicity via Inositol Trisphosphate Receptors and Loss of ATP Synthesis

Criddle, D. N., Murphy, J., Fistetto, G., Barrow, S. L., Tepikin, A. V., Neoptolemos, J. P., Sutton, R., & Petersen, O. H. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.12.031 · Cited by 268 · see citing works

Phosphatidylethanol in Blood as a Marker of Chronic Alcohol Use: A Systematic Review and Meta-Analysis

Viel, G., Rafael Boscolo-berto, A., Cecchetto, G., Fais, P., Nalesso, A., & Ferrara, S. D. (2012) · International Journal of Molecular Sciences · doi:10.3390/ijms131114788 · Cited by 253 · see citing works

Mitochondrial dysfunction induced by fatty acid ethyl esters, myocardial metabolites of ethanol.

Lange, L. G., & Sobel, B. E. (1983) · Journal of Clinical Investigation · doi:10.1172/jci111022 · Cited by 248 · see citing works

Regulation of behavioral maturation by a primer pheromone produced by adult worker honey bees

Léoncini, I., Conte, Y. L., Costagliola, G., Plettner, E., Toth, A. L., Wang, M., Huang, Z., Bécard, J.-M., Crauser, D., Slessor, K. N., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407652101 · Cited by 237 · see citing works

Detection Times for Urinary Ethyl Glucuronide and Ethyl Sulfate in Heavy Drinkers during Alcohol Detoxification

Helander, A., Böttcher, M. E., Fehr, C., Dahmen, N., & Beck, O. (2008) · Alcohol and Alcoholism · doi:10.1093/alcalc/agn084 · Cited by 224 · see citing works

Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites

Criddle, D. N., Raraty, M. G. T., Neoptolemos, J. P., Tepikin, A. V., Petersen, O. H., & Sutton, R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403431101 · Cited by 217 · see citing works

Comparison of Urinary Excretion Characteristics of Ethanol and Ethyl Glucuronide

Dahl, H., Stephanson, N. N., Beck, O., & Helander, A. (2002) · Journal of Analytical Toxicology · doi:10.1093/jat/26.4.201 · Cited by 202 · see citing works

The phospholipase D superfamily as therapeutic targets

Frohman, M. A. (2015) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2015.01.001 · Cited by 197 · see citing works

Formation of phosphatidylethanol in rat brain by phospholipase D

Gustavsson, L., & Alling, C. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)91507-5 · Cited by 181 · see citing works

Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

Werner, J., Laposata, M., Castillo, C. F.-D., Saghir, M., Iozzo, R. V., Lewandrowski, K. B., & Warshaw, A. L. (1997) · Gastroenterology · doi:10.1016/s0016-5085(97)70106-9 · Cited by 181 · see citing works

Normalization rate and cellular localization of phosphatidylethanol in whole blood from chronic alcoholics

Varga, A., Hansson, P., Johnson, G., & Alling, C. (2000) · Clinica Chimica Acta · doi:10.1016/s0009-8981(00)00291-6 · Cited by 174 · see citing works

Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis

Huang, W., Booth, D. M., Cane, M. C., Chvanov, M., Javed, M. A., Elliott, V. L., Armstrong, J. A., Dingsdale, H., Cash, N. J., Li, Y., et al. (2013) · Gut · doi:10.1136/gutjnl-2012-304058 · Cited by 174 · see citing works

Kinetics in serum and urinary excretion of ethyl sulfate and ethyl glucuronide after medium dose ethanol intake

Halter, C. C., Dresen, S., Auwärter, V., Wurst, F. M., & Weinmann, W. (2007) · International Journal of Legal Medicine · doi:10.1007/s00414-007-0180-8 · Cited by 169 · see citing works

A pharmacokinetic study of ethyl glucuronide in blood and urine: Applications to forensic toxicology

Høiseth, G., Bernard, J. P., Karinen, R., Johnsen, L., Helander, A., Christophersen, A. S., & Mørland, J. G. (2007) · Forensic Science International · doi:10.1016/j.forsciint.2007.01.005 · Cited by 165 · see citing works

An abnormal phospholipid in rat organs after ethanol treatment

Alling, C., Gustavsson, L., & Änggård, E. (1983) · FEBS Letters · doi:10.1016/0014-5793(83)80474-8 · Cited by 160 · see citing works

Activation of phospholipase D by chemotactic peptide in HL-60 granulocytes

Pai, J.-K., Siegel, M. I., Egan, R. W., & Billah, M. M. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(88)90528-1 · Cited by 160 · see citing works

Determination of Fatty Acid Ethyl Esters (FAEE) and Ethyl Glucuronide (EtG) in Hair: A Promising Way for Retrospective Detection of Alcohol Abuse During Pregnancy?

Pragst, F., & Yegles, M. (2008) · Therapeutic Drug Monitoring · doi:10.1097/ftd.0b013e318167d602 · Cited by 153 · see citing works

Combined use of fatty acid ethyl esters and ethyl glucuronide in hair for diagnosis of alcohol abuse: Interpretation and advantages

Pragst, F., Rothe, M., Moench, B., Hastedt, M., Herre, S., & Simmert, D. (2010) · Forensic Science International · doi:10.1016/j.forsciint.2009.12.028 · Cited by 146 · see citing works

Segmental determination of ethyl glucuronide in hair: A pilot study

Appenzeller, B. M. R., Agirman, R., Neuberg, P., Yegles, M., & Wennig, R. (2007) · Forensic Science International · doi:10.1016/j.forsciint.2007.01.025 · Cited by 141 · see citing works

Assessment of UDP-glucuronosyltransferase catalyzed formation of ethyl glucuronide in human liver microsomes and recombinant UGTs

Foti, R., & Fisher, M. B. (2005) · Forensic Science International · doi:10.1016/j.forsciint.2004.12.003 · Cited by 136 · see citing works

Fatty acid ethyl esters increase rat pancreatic lysosomal fragility.

Ps, H., Wilson, J. S., Apte, M. V., & Pirola, R. C. (1993) · PubMed · Cited by 133 · see citing works

Ethyl Linoleate in Meconium: A Biomarker for Prenatal Ethanol Exposure

Bearer, C. F., Lee, S., Salvator, A. E., Minnes, S., Swick, A. R., Yamashita, T. S., & Singer, L. T. (1999) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1999.tb04142.x · Cited by 132 · see citing works

Ca2 +‐mobilizing hormones elicit phosphatidylethanol accumulation via phospholipase D activation

Bocckino, S. B., Wilson, P. B., & Exton, J. H. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)81157-2 · Cited by 129 · see citing works

Ethanol Metabolites: Their Role in the Assessment of Alcohol Intake

Wurst, F. M., Thon, N., Yegles, M., Schrück, A., Preuss, U. W., & Weinmann, W. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12851 · Cited by 127 · see citing works

Fatty Acid Ethyl Esters in the Blood as Markers for Ethanol Intake

Doyle, K. (1996) · JAMA · doi:10.1001/jama.1996.03540140040024 · Cited by 125 · see citing works

Mass Spectrometric Identification of Ethyl Sulfate as an Ethanol Metabolite in Humans

Helander, A., & Beck, O. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2004.031252 · Cited by 116 · see citing works

Phorbol diesters stimulate the accumulation of phosphatidate, phosphatidylethanol, and diacylglycerol in three cell types. Evidence for the indirect formation of phosphatidylcholine-derived diacylglycerol by a phospholipase D pathway and direct formation of diacylglycerol by a phospholipase C pathway.

Huang, C. F., & Cabot, M. C. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)77193-7 · Cited by 114 · see citing works

2014 Consensus for the use of alcohol markers in hair for assessment of both abstinence and chronic excessive alcohol consumption

Kintz, P. (2014) · Forensic Science International · doi:10.1016/j.forsciint.2014.11.001 · Cited by 110 · see citing works

Phosphatidylethanol in Human Organs and Blood: A Study on Autopsy Material and Influences by Storage Conditions

Aradóttir, S., Seidl, S., Wurst, F. M., Jönsson, B., & Alling, C. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000145687.41646.e5 · Cited by 110 · see citing works

ETHYL GLUCURONIDE IN HUMAN HAIR

Skopp, G. (2000) · Alcohol and Alcoholism · doi:10.1093/alcalc/35.3.283 · Cited by 108 · see citing works

Characterization of the Pharmacokinetics of Phosphatidylethanol 16:0/18:1 and 16:0/18:2 in Human Whole Blood After Alcohol Consumption in a Clinical Laboratory Study

Javors, M. A., Hill‐Kapturczak, N., Roache, J. D., Karns‐Wright, T. E., & Dougherty, D. M. (2016) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13062 · Cited by 108 · see citing works

Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase.

Lange, L. G. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.13.3954 · Cited by 103 · see citing works

Limited palmitoyl-CoA penetration into microsomal vesicles as evidenced by a highly latent ethanol acyltransferase activity.

Polokoff, M. A., & Bell, R. M. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34480-0 · Cited by 97 · see citing works

Fatty acid ethyl esters decrease human hepatoblastoma cell proliferation and protein synthesis

Szczepiorkowski, Z. M., Dickersin, G. R., & Laposata, M. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90081-0 · Cited by 97 · see citing works

The characterization by gas-liquid chromatography of ethyl β-D-glucosiduronic acid as a metabolite of ethanol in rat and man

Jaakonmaki, P. I., Knox, K. L., Horning, E. C., & Horning, M. G. (1967) · European Journal of Pharmacology · doi:10.1016/0014-2999(67)90067-2 · Cited by 92 · see citing works

Characterization of enzymes involved in formation of ethyl esters of long-chain fatty acids in humans

Diczfalusy, M. A., Björkhem, I., Einarsson, C., Hillebrant, C.-G., & Alexson, S. E. H. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31590-x · Cited by 91 · see citing works

Clinical Sensitivity and Specificity of Meconium Fatty Acid Ethyl Ester, Ethyl Glucuronide, and Ethyl Sulfate for Detecting Maternal Drinking during Pregnancy

Himes, S. K., Dukes, K. A., Tripp, T. J., Petersen, J. M., Raffo, C., Burd, L., Odendaal, H. J., Elliott, A. J., Hereld, D., Signore, C. C., et al. (2015) · Clinical Chemistry · doi:10.1373/clinchem.2014.233718 · Cited by 90 · see citing works

PHOSPHATIDYLETHANOL FORMATION AND DEGRADATION IN HUMAN AND RAT BLOOD

Aradóttir, S. (2003) · Alcohol and Alcoholism · doi:10.1093/alcalc/agh003 · Cited by 88 · see citing works

Involvement of UDP-Glucuronosyltransferases UGT1A9 and UGT2B7 in Ethanol Glucuronidation, and Interactions with Common Drugs of Abuse

Saabi, A. A., Allorge, D., Sauvage, F., Tournel, G., Gaulier, J., Marquet, P., & Picard, N. (2012) · Drug Metabolism and Disposition · doi:10.1124/dmd.112.047878 · Cited by 82 · see citing works

Formation of fatty acid ethyl esters during chronic ethanol treatment in mice

Hungund, B. L., Goldstein, D. B., Villegas, F. J., & Cooper, T. B. (1988) · Biochemical Pharmacology · doi:10.1016/0006-2952(88)90288-2 · Cited by 82 · see citing works

Role of phosphatidylethanol in membranes. Effects on membrane fluidity, tolerance to ethanol, and activity of membrane-bound enzymes

Omodeo‐Salè, F., Lindi, C., Palestini, P., & Masserini, M. (1991) · Biochemistry · doi:10.1021/bi00223a026 · Cited by 81 · see citing works

Fetal Alcohol Syndrome and Fatty Acid Ethyl Esters

Bearer, C. F., Gould, S., Emerson, R. K., Kinnunen, P., & Cook, C. S. (1992) · Pediatric Research · doi:10.1203/00006450-199205000-00017 · Cited by 80 · see citing works

Fatty acid ethyl ester synthase in rat adipose tissue and its relationship to carboxylesterase.

Tsujita, T., & Okuda, H. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)35865-4 · Cited by 75 · see citing works

Ethanol Inhibits Astroglial Cell Proliferation by Disruption of Phospholipase D‐Mediated Signaling

Kötter, K., & Klein, J. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0732517.x · Cited by 72 · see citing works

Distribution of ethyl glucuronide in rib bone marrow, other tissues and body liquids as proof of alcohol consumption before death

Schloegl, H., Rost, T., Schmidt, W., Wurst, F. M., & Weinmann, W. (2005) · Forensic Science International · doi:10.1016/j.forsciint.2005.03.024 · Cited by 70 · see citing works

Oxidative and Non-Oxidative Metabolomics of Ethanol

Dinis‐Oliveira, R. J. (2016) · Current Drug Metabolism · doi:10.2174/1389200217666160125113806 · Cited by 69 · see citing works

Regulation of human PLD1 and PLD2 by calcium and protein kinase C

Siddiqi, A. R., Srajer, G., & Leslie, C. C. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(00)00049-5 · Cited by 68 · see citing works

Structural plasticity in the human cytosolic sulfotransferase dimer and its role in substrate selectivity and catalysis

Tibbs, Z. E., Rohn‐Glowacki, K. J., Crittenden, F., Guidry, A. L., & Falany, C. N. (2014) · Drug Metabolism and Pharmacokinetics · doi:10.1016/j.dmpk.2014.10.004 · Cited by 66 · see citing works

Pancreatic cholesterol esterases. 2. Purification and characterization of human pancreatic fatty acid ethyl ester synthase

Riley, D. J., Kyger, E. M., Spilburg, C. A., & Lange, L. G. (1990) · Biochemistry · doi:10.1021/bi00468a007 · Cited by 64 · see citing works

Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain

Lewis, S. S., Hutchinson, M. R., Zhang, Y., Hund, D. K., Maier, S. F., Rice, K. C., & Watkins, L. R. (2013) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2013.01.005 · Cited by 63 · see citing works

Molecular species analysis of a product of phospholipase D activation. Phosphatidylethanol is formed from phosphatidylcholine in phorbol ester- and bradykinin-stimulated PC12 cells.

Holbrook, P. G., Pannell, L. K., Murata, Y., & Daly, J. W. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41859-5 · Cited by 59 · see citing works

Metabolism of ethanol by human brain to fatty acid ethyl esters.

Laposata, E. A., Scherrer, D. E., Mazow, C., & Lange, L. G. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)61244-x · Cited by 58 · see citing works

Activation of a brain‐specific protein kinase C subspecies in the presence of phosphatidylethanol

Asaoka, Y., Kikkawa, U., Sekiguchi, K., Shearman, M. S., Kosaka, Y., Nakano, Y., Satoh, T., & Nishizuka, Y. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80735-x · Cited by 57 · see citing works

Placental Handling of Fatty Acid Ethyl Esters: Perfusion and Subcellular Studies

Chan, D., Knie, B., Boskovic, R., & Koren, G. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.066597 · Cited by 57 · see citing works

Can ethyl glucuronide be determined in post-mortem body fluids and tissues?

Wurst, F. M., Schüttler, R., Kempter, C., Seidl, S., Gilg, T., Jachau, K., & Alt, A. (1999) · Alcohol and Alcoholism · doi:10.1093/alcalc/34.2.262 · Cited by 56 · see citing works

Phosphatidylethanol Accumulation Promotes Intestinal Hyperplasia by Inducing ZONAB-Mediated Cell Density Increase in Response to Chronic Ethanol Exposure

Pannequin, J., Delaunay, N., Darido, C., Maurice, T., Crespy, P., Frohman, M. A., Balda, M. S., Matter, K., Joubert, D., Bourgaux, J., et al. (2007) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-07-0198 · Cited by 52 · see citing works

Non-Oxidative Metabolism of Ethanol by Rat Pancreatic Acini

Haber, P., Apte, M. V., Moran, C. S., Applegate, T. L., Pirola, R. C., Korsten, M. A., McCaughan, G. W., & Wilson, J. S. (2004) · Pancreatology · doi:10.1159/000077608 · Cited by 52 · see citing works

12-O-Tetradecanoylphorbol-13-acetate activates the synthesis of phosphatidylethanol in animal cells exposed to ethanol

Pai, J.-K., Liebl, E. C., Tettenborn, C. S., Ikegwuonu, F. I., & Mueller, G. C. (1987) · Carcinogenesis · doi:10.1093/carcin/8.1.173 · Cited by 51 · see citing works

The Synthesis of Fatty Acid Ethyl Ester by Carboxylester Lipase

Tsujita, T., & Okuda, H. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb19994.x · Cited by 49 · see citing works

In Heavy Drinkers, Fatty Acid Ethyl Esters Remain Elevated for Up to 99 Hours

Borucki, K., Dierkes, J., Wartberg, J., Westphal, S., Genz, A., & Luley, C. H. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00323.x · Cited by 49 · see citing works

Studies on ester sulfates

Vestermark, A., & Boström, H. (1959) · Experimental Cell Research · doi:10.1016/0014-4827(59)90302-7 · Cited by 49 · see citing works

Influence of ethanol dose and pigmentation on the incorporation of ethyl glucuronide into rat hair

Kharbouche, H., Steiner, N., Morelato, M., Staub, C., Boutrel, B., Mangin, P. J., Sporkert, F., & Augsburger, M. P. (2010) · Alcohol · doi:10.1016/j.alcohol.2010.05.001 · Cited by 48 · see citing works

Ethanol-induced fatty acid ethyl ester formation in vivo and in vitro in rat lung

Manautou, J. E., & Carlson, G. P. (1991) · Toxicology · doi:10.1016/0300-483x(91)90005-l · Cited by 48 · see citing works

Progress in Monitoring Alcohol Consumption and Alcohol Abuse by Phosphatidylethanol

Schröck, A., Thierauf, A., Wurst, F. M., Thon, N., & Weinmann, W. (2014) · Bioanalysis · doi:10.4155/bio.14.195 · Cited by 46 · see citing works

Synthesis and degradation of fatty acid ethyl esters by cultured hepatoma cells exposed to ethanol.

Laposata, E. A., Harrison, E. H., & Hedberg, E. B. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38725-3 · Cited by 42 · see citing works

Alternative sampling strategies for the assessment of alcohol intake of living persons

Kummer, N., Lambert, W. E., Samyn, N., & Stove, C. P. (2016) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2016.05.007 · Cited by 42 · see citing works

Fatty Acid Ethyl Ester Formation During Ethanol Metabolism in vivo.

Goodman, D. S., & Deykin, D. (1963) · Experimental Biology and Medicine · doi:10.3181/00379727-113-28277 · Cited by 41 · see citing works

Phosphatidylethanol formation and degradation in brains of acutely and repeatedly ethanol-treated rats

Lundqvist, C., Aradóttir, S., Alling, C., Boyano-Adánez, M. D. C., & Gustavsson, L. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90951-2 · Cited by 40 · see citing works

Synthesis of fatty acid esters of short-chain alcoh an acyltransferase in rat liver microsomes

Grigor, M. R., & Bell, I. C. (1973) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(73)90204-x · Cited by 39 · see citing works

Ethyl glucuronide and ethyl sulfate in autopsy samples 27 years after death

Politi, L., Morini, L., Mari, F., Groppi, A., & Bertol, E. (2008) · International Journal of Legal Medicine · doi:10.1007/s00414-008-0273-z · Cited by 39 · see citing works

Quantitative Determination of Ethyl Glucuronide in Sweat

Schummer, C., Appenzeller, B. M. R., & Wennig, R. (2008) · Therapeutic Drug Monitoring · doi:10.1097/ftd.0b013e318180c83d · Cited by 38 · see citing works

Role of phospholipase D signaling in ethanol‐induced inhibition of carbachol‐stimulated DNA synthesis of 1321N1 astrocytoma cells

Guizzetti, M., Thompson, B. D., Kim, Y., VanDeMark, K. L., & Costa, L. G. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02541.x · Cited by 38 · see citing works

Identification and preliminary characterization of UDP-glucuronosyltransferases catalyzing formation of ethyl glucuronide

Schwab, N., & Skopp, G. (2014) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-014-7675-1 · Cited by 35 · see citing works

Fatty acid ethyl ester-synthesizing activity of lipoprotein lipase from rat postheparin plasma.

Tsujita, T., & Okuda, H. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37544-0 · Cited by 34 · see citing works

Purification and Characterization of Rat Liver Microsomal Fatty Acid Ethyl and 2-Chloroethyl Ester Synthase and Their Relationship with Carboxylesterase (pI 6.1)

Kaphalia, B. S., Fritz, R. R., & Ansari, G. A. S. (1997) · Chemical Research in Toxicology · doi:10.1021/tx960079e · Cited by 34 · see citing works

Inhibition of the metabolism of phosphatidylethanol and phosphatidic acid, and stimulation of insulin release, by propranolol in intact pancreatic islets

Metz, S. A., & Dunlop, M. (1991) · Biochemical Pharmacology · doi:10.1016/0006-2952(91)90470-p · Cited by 33 · see citing works

Ethyl-glucuronide and ethyl-sulfate in placental and fetal tissues by liquid chromatography coupled with tandem mass spectrometry

Morini, L., Romero, M. F., Pichini, S., García‐Algar, Ó., Danesino, P., Groppi, A., & Maldonado, A. L. (2011) · Analytical Biochemistry · doi:10.1016/j.ab.2011.06.038 · Cited by 33 · see citing works

Phosphatidylethanol Affects Inositol 1,4,5‐Trisphosphate Levels in NG108‐15 Neuroblastoma × Glioma Hybrid Cells

Lundqvist, C., Rodriguez, F. D., Simonsson, P., Alling, C., & Gustavsson, L. (1993) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1993.tb03209.x · Cited by 32 · see citing works

Phosphatidylethanol in Rat Organs After Ethanol Exposure

Aradóttir, S., Lundqvist, C., & Alling, C. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200204000-00012 · Cited by 32 · see citing works

Purification and Characterization of Human Heart Fatty Acid Ethyl Ester Synthase/Carboxylesterase

Bora, P. S. (1996) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1996.0195 · Cited by 31 · see citing works

Production of phosphatidylethanol by phospholipase D phosphatidyl transferase in intact or dispersed pancreatic islets: Evidence for the in situ metabolism of phosphatidylethanol

Metz, S. A., & Dunlop, M. (1990) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(90)90663-j · Cited by 31 · see citing works

Formation of fatty acid ethyl esters in rat liver microsomes

Diczfalusy, M. A., Björkhem, I., Einarsson, C., & Alexson, S. E. H. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00052.x · Cited by 28 · see citing works

Fatty acid ethyl ester synthesis by human liver microsomes

Treloar, T., Madden, L. J., Winter, J. S., Smith, J. L., & de Jersey, J. (1996) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(95)00199-9 · Cited by 28 · see citing works

Reduction of fatty acid ethyl ester accumulation by ganglioside GM1 in rat fetus exposed to ethanol

Hungund, B. L., & Gokhale, V. S. (1994) · Biochemical Pharmacology · doi:10.1016/0006-2952(94)90511-8 · Cited by 24 · see citing works

Fatty acid ethyl ester synthesis by the isolated perfused rat heart

Chang, W., Waltenbaugh, C. R., & Borensztajn, J. (1997) · Metabolism · doi:10.1016/s0026-0495(97)90081-0 · Cited by 23 · see citing works

Fatty Acid Ethyl Esters Are Less Toxic Than Their Parent Fatty Acids Generated during Acute Pancreatitis

Patel, K. S., Durgampudi, C., Noel, P., Trivedi, R. N., de Oliveira, C., & Singh, V. P. (2016) · American Journal Of Pathology · doi:10.1016/j.ajpath.2015.11.022 · Cited by 23 · see citing works

Phosphatidylethanol stimulates the plasma-membrane calcium pump from human erythrocytes

Meylin, S. U. J. U., Davila, M., Poleo, G. A., Docampo, R., & Benaím, G. (1996) · Biochemical Journal · doi:10.1042/bj3170933 · Cited by 22 · see citing works

Degradation of phosphatidylethanol counteracts the apparent phospholipase D-mediated formation in heart and other organs

Brühl, A. B. (2003) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(03)00090-8 · Cited by 20 · see citing works

Light and electron microscopic study of the hindgut of the ant (Formica nigricans, Hymenoptera): I. structure of the ileum

Villaro, A. C., Garayoa, M., Lezaun, M. J., & Sesma, P. (1999) · Journal of Morphology · doi:10.1002/(sici)1097-4687(199912)242:3 · Cited by 20 · see citing works

Determination of Ethylglucuronide in Oral Fluid by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry

Hegstad, S., Johnsen, L., Mørland, J. G., & Christophersen, A. S. (2009) · Journal of Analytical Toxicology · doi:10.1093/jat/33.4.204 · Cited by 20 · see citing works

The Metabolism of Ethyl Esters of Fatty Acids in Adipose Tissue of Rats Chronically Exposed to Ethanol

Pergola, G. D., Kjellström, C., Holm, C., CONRADI, N. G., Pettersson, P., & Björntorp, P. A. (1991) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1991.tb01853.x · Cited by 20 · see citing works

Ethanol Sulfation by the Human Cytosolic Sulfotransferases: A Systematic Analysis

Kurogi, K., Davidson, G., Mohammed, Y. I., Williams, F. E., Liu, M., Sakakibara, Y., Suiko, M., & Liu, M. (2012) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b12-00547 · Cited by 19 · see citing works

Purification and characterization of rat hepatic microsomal low molecular weight fatty acid ethyl ester synthase and its relationship to carboxylesterases

Kaphalia, B. S., & Ansari, G. A. S. (2001) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.14 · Cited by 18 · see citing works

Phosphatidylethanol counteracts calcium-induced membrane fusion but promotes proton-induced fusion

Bondeson, J., & Sundler, R. (1987) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(87)90407-x · Cited by 18 · see citing works

Alcoholysis of the endogenous phosphate esters in rats treated with large doses of ethanol

Tomaszewski, M., & Buchowicz, J. (1972) · Biochemical Journal · doi:10.1042/bj1290183 · Cited by 17 · see citing works

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism

Heier, C., Taschler, U., Radulovic, M., Aschauer, P., Eichmann, T. O., Grond, S., Wolinski, H., Oberer, M., Zechner, R., Kohlwein, S. D., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.705541 · Cited by 17 · see citing works

Phosphatidylethanol stimulates calcium-dependent cytosolic phospholipase A2 activity of a macrophage cell line (RAW 264.7)

Chang, C., Farrell, K. R., & Baker, R. C. (2000) · Journal of Biomedical Science · doi:10.1007/bf02253250 · Cited by 14 · see citing works

Fatty Acid Ethyl Esters Disrupt Neonatal Alveolar Macrophage Mitochondria and Derange Cellular Functioning

Mohan, S. S., Ping, X. D., Harris, F. L., Ronda, N. J., Brown, L. A. S., & Gauthier, T. W. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12647 · Cited by 14 · see citing works

Phosphatidylethanols in Breath: A Possible Noninvasive Screening Test for Heavy Alcohol Consumption

Helander, A., Ullah, S., & Beck, O. (2015) · Clinical Chemistry · doi:10.1373/clinchem.2015.239848 · Cited by 12 · see citing works

Rapid Fatty Acid Ethyl Ester Synthesis by Porcine Myocardium Upon Ethanol Infusion into the Left Anterior Descending Coronary Artery

Yoerger, D. M., Best-Popescu, C. A., McQuillan, B., Supple, G. E., Guererro, J. L., Cluette‐Brown, J. E., Hasaba, A., Picard, M. H., Stone, J. R., & Laposata, M. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.050537 · Cited by 12 · see citing works

Identification and characterization of sulfonyltransferases catalyzing ethyl sulfate formation and their inhibition by polyphenols

Stachel, N., & Skopp, G. (2015) · International Journal of Legal Medicine · doi:10.1007/s00414-015-1159-5 · Cited by 11 · see citing works

Induction of Apoptosis and Necrosis in Human Peripheral Blood Mononuclear Cells by Fatty Acid Ethyl Esters

Alhomsi, K., Selig, M. K., Šuštić, T., Katrangi, E., Weissig, V., & Laposata, M. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00597.x · Cited by 11 · see citing works

Mechanism of differential inhibition of hepatic and pancreatic fatty acid ethyl ester synthase by inhibitors of serine-esterases: in vitro and cell culture studies

Kaphalia, B. S., Mericle, K. A., & Ansari, G. A. S. (2004) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2004.03.018 · Cited by 9 · see citing works

Phosphatidylethanol inhibits phosphatidylinositol-phospholipase C activity in a competitive manner with phosphatidylinositol-4,5-bisphosphate

Nishida, A. (1997) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(96)01328-2 · Cited by 9 · see citing works

Comparative analysis of glucuronidation of ethanol in treeshrews, rats and humans

Fu, J., Liu, H., Xing, H., Sun, H., Ma, Z., & Wu, B. (2014) · Xenobiotica · doi:10.3109/00498254.2014.926573 · Cited by 6 · see citing works

The metabolism of aliphatic alcohols; glucuronide formation.

Ia, K., Jn, S., & Williams, R. T. (1951) · PubMed · Cited by 6 · see citing works

Pathophysiological Aspects of Alcohol Metabolism in the Liver

Hyun, J., Han, J., Lee, C., Yoon, M., & Jung, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115717 · Cited by 324 · see citing works

Recent Advances in Understanding of Pathogenesis of Alcohol-Associated Liver Disease

Wu, X., Fan, X., Miyata, T., Kim, A., Cajigas-Du Ross, C. K., Ray, S., Huang, E., Taiwo, M., Arya, R., Wu, J., et al. (2023) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-031521-030435 · Cited by 289 · see citing works

Alcohol and Human Health: What Is the Evidence?

Hendriks, H. (2020) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-032519-051827 · Cited by 217 · see citing works

Colorectal Cancer and Alcohol Consumption—Populations to Molecules

Rossi, M., Anwar, M. J., Usman, A., Keshavarzian, A., & Bishehsari, F. (2018) · Cancers · doi:10.3390/cancers10020038 · Cited by 208 · see citing works

Alcohol Biomarkers in Clinical and Forensic Contexts

Andresen‐Streichert, H., Müller, A., Glahn, A., Skopp, G., & Sterneck, M. R. (2018) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2018.0309 · Cited by 190 · see citing works

Impact of Alcohol Consumption on Male Fertility Potential: A Narrative Review

Finelli, R., Mottola, F., & Agarwal, A. K. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19010328 · Cited by 124 · see citing works

Alcohol-Associated Tissue Injury: Current Views on Pathophysiological Mechanisms

Simon, L., Souza‐Smith, F. M., & Molina, P. E. (2022) · Annual Review of Physiology · doi:10.1146/annurev-physiol-060821-014008 · Cited by 97 · see citing works

The Role of Alcohol Metabolism in the Pathology of Alcohol Hangover

Mackus, M., van de Loo, A. J. A. E., Garssen, J., Kraneveld, A. D., Scholey, A. B., & Verster, J. C. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9113421 · Cited by 91 · see citing works

Phosphatidylethanol (PEth) in Blood as a Marker of Unhealthy Alcohol Use: A Systematic Review with Novel Molecular Insights

Perilli, M., Toselli, F., Franceschetto, L., Cinquetti, A., Ceretta, A., Cecchetto, G., & Viel, G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512175 · Cited by 88 · see citing works

Consistency between self-reported alcohol consumption and biological markers among patients with alcohol use disorder – A systematic review

Nielsen, D. G., Andersen, K., Nielsen, A. S., Juhl, C. B., & Mellentin, A. I. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.006 · Cited by 84 · see citing works

Oxidative stress in alcoholic liver disease, focusing on proteins, nucleic acids, and lipids: A review

Lai, W., Zhang, J., Sun, J., Min, T., Bai, Y., He, J., Cao, H., Che, Q., Guo, J., & Su, Z. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134809 · Cited by 87 · see citing works

The multiple facets of acetyl-CoA metabolism: Energetics, biosynthesis, regulation, acylation and inborn errors

Wang, Y., Yang, H., Geerts, C., Fürtös, A., Waters, P. J., Cyr, D., Wang, S., & Mitchell, G. A. (2022) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2022.106966 · Cited by 73 · see citing works

Translational Approaches with Antioxidant Phytochemicals against Alcohol-Mediated Oxidative Stress, Gut Dysbiosis, Intestinal Barrier Dysfunction, and Fatty Liver Disease

Ballway, J. W., & Song, B.-J. (2021) · Antioxidants · doi:10.3390/antiox10030384 · Cited by 68 · see citing works

Diagnostic Accuracy of Biomarkers of Alcohol Use in Patients With Liver Disease: A Systematic Review

Arnts, J., Vanlerberghe, B. T. K., Roozen, S., Crunelle, C. L., Masclee, A., Damink, S. W. M. O., Heeren, R. M. A., van Nuijs, A. L. N., Neels, H. M., Nevens, F., et al. (2020) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14512 · Cited by 57 · see citing works

Alcohol and breast cancer

Starek‐Świechowicz, B., Budziszewska, B., & Starek, A. (2022) · Pharmacological Reports · doi:10.1007/s43440-022-00426-4 · Cited by 61 · see citing works

Alcoholic liver disease: a new insight into the pathogenesis of liver disease

Park, S. H., Lee, Y., Sim, J., Seo, S., & Seo, W. (2022) · Archives of Pharmacal Research · doi:10.1007/s12272-022-01392-4 · Cited by 54 · see citing works

Uncovering the impact of alcohol on internal organs and reproductive health: Exploring TLR4/NF‐kB and CYP2E1/ROS/Nrf2 pathways

Kong, E. Q. Z., Subramaniyan, V., & Lubau, N. S. A. (2024) · Animal Models and Experimental Medicine · doi:10.1002/ame2.12436 · Cited by 47 · see citing works

Phosphatidylethanol in steatotic liver disease

Torp, N., Israelsen, M. E., Thiele, M. S., Rinella, M. E., & Krag, A. A. (2025) · Journal of Hepatology · doi:10.1016/j.jhep.2025.07.019 · Cited by 44 · see citing works

Cellular Bioenergetics: Experimental Evidence for Alcohol-induced Adaptations

Simon, L., & Molina, P. E. (2022) · Function · doi:10.1093/function/zqac039 · Cited by 42 · see citing works

Ion exchange in supercritical fluid chromatography tandem mass spectrometry (SFC-MS/MS): Application for polar and ionic drugs and metabolites in forensic and anti-doping analysis

Xhaferaj, M., Nägele, E., & Parr, M. K. (2019) · Journal of Chromatography A · doi:10.1016/j.chroma.2019.460726 · Cited by 41 · see citing works

Harnessing the potential of probiotics in the treatment of alcoholic liver disorders

Mishra, G., Singh, P. N. D., Molla, M., Yimer, Y. S., Dinda, S. C., Chandra, P., Singh, B. K., Dagnew, S. B., Assefa, A. N., & Ewunetie, A. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1212742 · Cited by 39 · see citing works

Metabolic dysfunction and alcohol-associated liver disease (MetALD)

Gao, B., Arab, J. P., Liangpunsakul, S., Ding, W., Szabó, G., Mehal, W. Z., Wang, H., He, Y., Stärkel, P., Llorente, C., et al. (2025) · eGastroenterology · doi:10.1136/egastro-2025-100319 · Cited by 42 · see citing works

Recent advances in alcohol metabolism: from the gut to the brain

Goldman, M. R., Molina-Castro, M., Etkins, J. C., Koide, T. L., Ramchandani, V. A., Plawecki, M. H., Mennella, J. A., & Pepino, M. Y. (2025) · Physiological Reviews · doi:10.1152/physrev.00053.2024 · Cited by 34 · see citing works

Quantitation of phosphatidylethanol in dried blood after volumetric absorptive microsampling

Uytfanghe, K. V., Fernández, M. D. M. R., Vos, A. D., Wille, S. M. R., & Stove, C. P. (2020) · Talanta · doi:10.1016/j.talanta.2020.121694 · Cited by 30 · see citing works

Ethanol, neurosteroids and cellular stress responses: Impact on central nervous system toxicity, inflammation and autophagy

Fujii, C., Zorumski, C. F., & Izumi, Y. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.01.026 · Cited by 30 · see citing works

Dietary Nutrient Intake, Alcohol Metabolism, and Hangover Severity

Verster, J. C., Vermeulen, S. A., van de Loo, A. J. A. E., Balikji, S., Kraneveld, A. D., Garssen, J., & Scholey, A. B. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8091316 · Cited by 26 · see citing works

Alcohol, Resistance Exercise, and mTOR Pathway Signaling: An Evidence-Based Narrative Review

Levitt, D., Luk, H.-Y., & Vingren, J. (2022) · Biomolecules · doi:10.3390/biom13010002 · Cited by 24 · see citing works

Gut microbiota interacts with inflammatory responses in acute pancreatitis

Wu, L., Hu, J., Yi, X.-L., Lv, J., Yao, J., Tang, W., Zhang, S., & Wan, M. (2023) · Therapeutic Advances in Gastroenterology · doi:10.1177/17562848231202133 · Cited by 28 · see citing works

Biochemical Mechanisms Associating Alcohol Use Disorders with Cancers

Rodriguez, F. D., & Coveñas, R. (2021) · Cancers · doi:10.3390/cancers13143548 · Cited by 27 · see citing works

Lysosome and proteasome dysfunction in alcohol-induced liver injury

Donohue, T., Osna, N., Kharbanda, K., & Thomes, P. (2019) · Liver Research · doi:10.1016/j.livres.2019.11.001 · Cited by 16 · see citing works

Molecular mechanisms of ethanol biotransformation: enzymes of oxidative and nonoxidative metabolic pathways in human

Kubiak-Tomaszewska, G., Tomaszewski, P., PACHECKA, J., Struga, M., Olejarz, W., Mielczarek‐Puta, M., & Nowicka, G. (2020) · Xenobiotica · doi:10.1080/00498254.2020.1761571 · Cited by 23 · see citing works

A physiologically-based digital twin for alcohol consumption—predicting real-life drinking responses and long-term plasma PEth

Podéus, H., Simonsson, C., Nasr, P., Ekstedt, M., Kechagias, S., Lundberg, P., Lövfors, W., & Cedersund, G. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01089-6 · Cited by 22 · see citing works

Understanding the Role of Alcohol in Metabolic Dysfunction and Male Infertility

Genchi, V. A., Cignarelli, A., Sansone, A., Yannas, D., Valentina, L. D., Livraghi, D. R., Spaggiari, G., & Santi, D. (2024) · Metabolites · doi:10.3390/metabo14110626 · Cited by 20 · see citing works

Post-translational modifications of histone and non-histone proteins in epigenetic regulation and translational applications in alcohol-associated liver disease: Challenges and research opportunities

Rungratanawanich, W., Ballway, J. W., Wang, X., Won, K., Hardwick, J. P., & Song, B. (2023) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2023.108547 · Cited by 22 · see citing works

Alcohol-Metabolizing Enzymes, Liver Diseases and Cancer

Liu, T., Zhang, F., Feng, Y., Han, P., & Gao, Y. (2025) · Seminars in Liver Disease · doi:10.1055/a-2551-3320 · Cited by 19 · see citing works

A review on the protective effect of active components in Antrodia camphorata against alcoholic liver injury

Liu, X., Yu, S., Zhang, Y., Zhang, W., Zhong, H., Lu, X., & Guan, R. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115740 · Cited by 19 · see citing works

Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for characterization of ethanol and acetaldehyde metabolism

Zhu, L., Pei, W., Thiele, I., & Mahadevan, R. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009110 · Cited by 18 · see citing works

Wine, Polyphenols, and the Matrix Effect: Is Alcohol Always the Same?

Miraldi, E., Baini, G., Biagi, M., Cappellucci, G., Giordano, A., Vaccaro, F., & Bertelli, A. A. E. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189796 · Cited by 17 · see citing works

Sensitivity of SARS-CoV-2 towards Alcohols: Potential for Alcohol-Related Toxicity in Humans

Basak, D., & Deb, S. (2021) · Life · doi:10.3390/life11121334 · Cited by 17 · see citing works

Ethanol Metabolism and Melanoma

Zhai, Z., Yamauchi, T., Shangraw, S., Hou, V., Matsumoto, A., & Fujita, M. (2023) · Cancers · doi:10.3390/cancers15041258 · Cited by 15 · see citing works

Lipidomic signature of serum from the rats exposed to alcohol for one year

Li, H., Xu, W., Jiang, L., Gu, H., Li, M., Zhang, J., Guo, W., Deng, P., Long, H., Bu, Q., et al. (2018) · Toxicology Letters · doi:10.1016/j.toxlet.2018.05.011 · Cited by 16 · see citing works

Protective effects and therapeutic applications of ellagic acid against natural and synthetic toxicants: A review article.

Naraki, K., Rameshrad, M., & Hosseinzadeh, H. (2022) · PubMed Central · doi:10.22038/ijbms.2022.64790.14267 · Cited by 15 · see citing works

Estimating the time of last drinking from blood ethyl glucuronide and ethyl sulphate concentrations

Wang, L., Zhang, W. Y., Wang, R., Guang, Y., Zhang, D., Zhang, C., Hu, M., Wei, Z., Zhang, W., Yun, K., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-18527-8 · Cited by 14 · see citing works

Comparison of maternal venous blood metabolomics collected as dried blood spots, dried blood microsamplers, and plasma for integrative environmental health research

Petrick, L. M., Guan, H., Page, G. P., Dolios, G., Niedzwiecki, M. M., Wright, R. O., & Wright, R. J. (2024) · Environment International · doi:10.1016/j.envint.2024.108663 · Cited by 14 · see citing works

The Role of Oxidative Inactivation of Phosphatase PTEN and TCPTP in Fatty Liver Disease

Huu, T. N., Park, J., Zhang, Y., Thanh, H. D., Park, I., Choi, J. M., Yoon, H. J., Park, S. C., Woo, H. A., & Lee, S.-R. (2023) · Antioxidants · doi:10.3390/antiox12010120 · Cited by 12 · see citing works

Monitoring the use of alcohol—A critical overview of the state‐of‐the‐art biomarkers

Uytfanghe, K. V., Boosere, E. D., & Stove, C. P. (2022) · Wiley Interdisciplinary Reviews Forensic Science · doi:10.1002/wfs2.1457 · Cited by 11 · see citing works

Alcohol as a Non-UV Social-Environmental Risk Factor for Melanoma

Yamauchi, T., Shangraw, S., Zhai, Z., Menon, D. R., Batta, N., Dellavalle, R. P., & Fujita, M. (2022) · Cancers · doi:10.3390/cancers14205010 · Cited by 12 · see citing works

Phosphatidylethanol blood analysis

Hakim, F., Wiart, J., Ménard, O., Allorge, D., & Gaulier, J. (2019) · Annales de biologie clinique · doi:10.1684/abc.2019.1499 · Cited by 11 · see citing works

Neurotoxicity of Chronic Alcohol Exposure: Mechanistic Insights, Cellular Disruption, and Emerging Therapeutic Strategies

Gołaszewski, P., Wawrzyniak, A., Kłosowicz, M., Burbelka, A., & Balawender, K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms27010299 · Cited by 10 · see citing works

ADH and ALDH Polymorphisms in Alcoholism and Alcohol Misuse/Dependence

Vaswani, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813125-1.00004-0 · Cited by 9 · see citing works

High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats

Matos‐Sousa, J. M., Souza‐Monteiro, D., dos Santos, V. R. N., Ferreira, M. K. M., Frazão, D. R., Chemelo, V. S., Bittencourt, L. O., de Moura, J. D. M., Maia, C. D. S. F., Collares, F. M., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e40163 · Cited by 8 · see citing works

Dysregulated hepatic alcohol metabolism: a key factor involved in the pathogenesis of alcohol-associated liver disease

Srinivasan, M. P., Kota, S., Bhopale, K. K., Caracheo, A. A., Kaphalia, L., Linares, J., Romsdahl, T. B., Russell, W. K., Popov, V. L., Boor, P., et al. (2025) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00394.2024 · Cited by 7 · see citing works

Biomarkers for monitoring alcohol sobriety after liver transplantation for alcoholic liver disease

Liu, J., & Man, K. (2023) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.16269 · Cited by 6 · see citing works

Autobrewery Syndrome and Endogenous Ethanol Production in Patients with MASLD: A Perspective from Chronic Liver Disease

Andaloro, S., Gaetano, V. D., Cardone, F., Ianiro, G., Cerrito, L., Pallozzi, M., Stella, L., Gasbarrini, A., & Ponziani, F. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26157345 · Cited by 5 · see citing works

Role of Biomarkers to Assess the Use of Alcohol

Shetty, A., Torre, S. A. D. L., Ibrahim, B., Hong, A., Meza, J., & Saab, S. (2023) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0000000000001852 · Cited by 5 · see citing works

Nutritional and microbiota-based therapeutic intervention for alcohol-associated liver disease: Pathogenesis to therapeutic insights.

Rangra, S., Rana, D., Prajapati, A., Benival, D., Dwivedi, P., & Mandoli, A. (2024) · Life Science · doi:10.1016/j.lfs.2024.122852 · Cited by 5 · see citing works

Impact of binge drinking on alcoholic liver disease

Kang, J., Park, S. H., Khanam, M., Park, S. B., Shin, S., & Seo, W. (2025) · Archives of Pharmacal Research · doi:10.1007/s12272-025-01537-1 · Cited by 5 · see citing works

Restorative Effects of Aloe Vera Gel on Alcohol Induced Hepato-Nephrocellular Dysfunction

Akinloye, D. I., Ugbaja, R. N., Dosumu, O. A., Akamo, A. J., James, A. S., & Adeyemo, A. (2021) · Folia veterinaria · doi:10.2478/fv-2021-0001 · Cited by 5 · see citing works

Multiomics Approach Captures Hepatic Metabolic Network Altered by Chronic Ethanol Administration

Sakallioglu, I. T., Tripp, B. A., Kubik, J. L., Casey, C. A., Thomes, P. G., & Powers, R. (2022) · Biology · doi:10.3390/biology12010028 · Cited by 5 · see citing works

Determination by UHPLC‐QTOF‐HRMS of Phosphatidylethanol (PEth) in Dried Blood Spots: Method Validation and Practical Application of a Rising Alcohol Abuse Biomarker With Minimally Invasive Sampling

Ververi, C., Massano, M., Alladio, E., Salomone, A., & Vincenti, M. (2025) · Biomedical Chromatography · doi:10.1002/bmc.70081 · Cited by 4 · see citing works

Epigenetics and Lifestyle: The Impact of Stress, Diet, and Social Habits on Tissue Homeostasis

Pérez, R. F., Santamarina‐Ojeda, P., Fernández, A. F., & Fraga, M. F. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814879-2.00020-0 · Cited by 3 · see citing works

Phospholipase D: its role in metabolism processes and disease development

Ramenskaya, G. V., Melnik, E. V., & Петухов, А. Е. (2018) · Biomeditsinskaya Khimiya · doi:10.18097/pbmc20186401084 · Cited by 4 · see citing works

The potential role of calcitonin gene-related peptide antagonists for the management of hangover headaches

Hakim, S. M. (2025) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0000000000001553 · Cited by 3 · see citing works

Alcohol: Absorption, metabolism, and physiological effects

Rajendram, R., Hunter, R. J., & Preedy, V. R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821848-8.00133-5 · Cited by 3 · see citing works

Evaluation of harmful drinking among professional drivers by direct ethanol biomarkers and its relation with psychological distress

Artmann, A. D. C., Tegner, M., Guterres, F. D. S., Bastiani, M. F., Linden, R., & Antunes, M. V. (2024) · Traffic Injury Prevention · doi:10.1080/15389588.2024.2349282 · Cited by 2 · see citing works

Aktuelles zu Alkoholkonsum- markern bei forensischen und suchtmedizinischen Fragestellungen

Skopp, G., & Mußhoff, F. (2020) · SUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice · doi:10.1024/0939-5911/a000687 · Cited by 2 · see citing works

Regulation Mechanism and Potential Value of Active Substances in Spices in Alcohol–Liver–Intestine Axis Health

Huang, J., Huang, T., & Li, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073728 · Cited by 2 · see citing works

Wastewater Microbiome Analysis for Population Alcohol Abuse

Wu, J., Chen, Y., Zhao, J., Prosun, T. A., O'Brien, J. W., Coin, L., Hai, F. I., Sanderson‐Smith, M. L., & Jiang, G. (2024) · Water · doi:10.3390/w16152149 · Cited by 2 · see citing works

Fatty Acid Levels in Striated Muscles of Chronic Alcohol-Fed Rats

Kulagina, T. P., Gritsyna, Y. V., Aripovsky, A. V., Zhalimov, V. K., & Vikhlyantsev, I. M. (2018) · BIOPHYSICS · doi:10.1134/s0006350918050135 · Cited by 2 · see citing works

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de Santana, B. F., de Almeida, M. E. F., Barakat, B., Vinha, L. I. D. L., Ribeiro, M. G. C., & Parussolo, G. S. (2023) · Research Society and Development · doi:10.33448/rsd-v12i3.40668 · Cited by 2 · see citing works

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Lappas, N. T., & Lappas, C. M. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819286-3.00021-x · Cited by 1 · see citing works

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Dawidowska, J., Jacyna, J., Wawrzyniak, R., Kaliszan, M., & Markuszewski, M. J. (2025) · Biomedicines · doi:10.3390/biomedicines13071688 · Cited by 1 · see citing works

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Shetty, A., Rahal, K., Meza, J., & Saab, S. (2026) · Digestive Diseases and Sciences · doi:10.1007/s10620-026-09807-8 · Cited by 1 · see citing works

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Mei, J., Cheng, F., Jiasheng, W. A. N. G., Fang, C., Rao, Z., Zhang, X., & Zhang, W. (2026) · Food Research International · doi:10.1016/j.foodres.2026.119742 · Cited by 1 · see citing works

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Papaseit, E., Muga, R., Zuluaga, P., Sanvisens, A., & Farré, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-813125-1.00060-x · Cited by 1 · see citing works

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Janeski, J. D., Naik, V. D., Carabulea, A. L., Jiang, H., & Ramadoss, J. (2024) · Nutrients · doi:10.3390/nu16101409 · Cited by 1 · see citing works

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Sutsko, I. P., Semenenya, I. N., & Shlyahtun, A. H. (2021) · Hepatology and Gastroenterology · doi:10.25298/2616-5546-2021-5-2-132-137 · Cited by 1 · see citing works

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Hakim, F. (2022) · doi:10.70675/c14c15ccz90efz4347za5d7z198cb3dd3c96 · Cited by 1 · see citing works

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Ramenskaya, G. V., Melnik, E. V., & Петухов, А. Е. (2018) · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry · doi:10.1134/s199075081803006x

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Nichols, L. E. (2021) · doi:10.23889/suthesis.58274

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MUTLU, E., Okudan, M., & Aşıcıoğlu, F. (2022) · Turkiye Klinikleri Journal of Forensic Medicine and Forensic Sciences · doi:10.5336/forensic.2021-84198

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Ott, I. R., Tegner, M., Gerbase, F. E., Sagrilo, O. P. Z., Linden, R., & Antunes, M. V. (2022) · Química Nova · doi:10.21577/0100-4042.20170926

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Mußhoff, F. (2024) · Suchttherapie · doi:10.1055/a-2340-7514

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Shi, Q., Wang, L., Li, W., Feng, Y., Wei, Z., & Yun, K. (2024) · Scientific Reports · doi:10.1038/s41598-024-75206-6

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Liut, J., Madea, B., Meißner, D., Lützen, A., Javidi, S., Heß, C., & Krämer, M. (2024) · Journal of Analytical Toxicology · doi:10.1093/jat/bkae095

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Kaur, S., & Tripathi, D. M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-99478-1.00005-5

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Suefusa-Shimogori, Y., Wakuda, H., Nureki, S., Kai, M., Sakamoto, D., Mori, N., Fujisawa, T., Narihara, M., & Uemura, N. (2025) · Forensic Toxicology · doi:10.1007/s11419-025-00747-y

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Molina, P. E., & Simon, L. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-34258-5.00002-5

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Lee, S., Baek, A., Sung, B., Yang, B. W., Yang, S., Kim, S., Yang, J.-U., Ko, I. O., Lee, G. H., Park, J. A., et al. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c03268

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Bucher, S. (2018) · theses.fr (ABES) · doi:10.70675/882ccc94z02d7z46fdzbed9z5722a414c8e8

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Pálóczi, J., Byerley, L. O., & Primeaux, S. D. (2026) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2026.109038

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Chen, C. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.118567

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Laposata, E. A., & Lange, L. G. (1986) · Science · doi:10.1126/science.3941913 · Cited by 493 · see citing works

Fatty acid ethyl esters: Nonoxidative ethanol metabolites with emerging biological and clinical significance

Laposata, M. (1999) · Lipids · doi:10.1007/bf02562318 · Cited by 39 · see citing works

Non-oxidative Ethanolmetaboliten als Alkoholkonsummarker im Vergleich zu traditionellen Markern: Weitere Hinweise für die Bedeutung von Ethylglucuronid, Fettsäureethylestern und Phosphatidylethanol

Wurst, F. M., Wiesbeck, G. A., Forster, S., Bechtel, G., Wolfersdorf, M., Huber, P., Alexson, S. E. H., Gilg, T., Jachau, K., Varga, A., et al. (2003) · FreiDok plus (Universitätsbibliothek Freiburg)

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Dinis‐Oliveira, R. J. (2016) · Current Drug Metabolism · doi:10.2174/1389200217666160125113806 · Cited by 69 · see citing works

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Haber, P., Apte, M. V., Moran, C. S., Applegate, T. L., Pirola, R. C., Korsten, M. A., McCaughan, G. W., & Wilson, J. S. (2004) · Pancreatology · doi:10.1159/000077608 · Cited by 52 · see citing works