The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Biodegradation of a polyurethane in vitro
Abstract
This study examines the effect of in vitro exposure to enzymes on the performance properties of Biomer®, a segmented polyetherurethane used in a number of blood‐contacting devices such as catheters, heart assist pumps, and chambers for artificial hearts. The ultrathin samples were treated with two proteolytic enzymes, papain and urease, for periods of 1–6 months at 37°C. The treated Biomer® samples were subjected to chemical and physical analysis. Effects of biodegradation by the enzymes were assessed by fatigue tests, gel permeation chromatography (GPC), and attenuated total reflectance‐Fourier transform infrared (ATR‐FTIR) analysis. Papain was found to be more effective in degrading the polymer than urease. Mechanisms for enzymic degradation are proposed.
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Cites
In vivo biocompatibility studies. I. The cage implant system and a biodegradable hydrogel
Marchant, R., Hiltner, A., Hamlin, C., Rabinovitch, A., Slobodkin, R., & Anderson, J. M. (1983) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820170209 · Cited by 181
Self-citationPhysicochemical characterization and in vivo blood tolerability of cast and extruded biomer
Lelah, M. D., Lambrecht, L. K., Young, B. R., & Cooper, S. L. (1983) · Journal of Biomedical Materials Research · doi:10.1002/jbm.820170102 · Cited by 134
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Degradation and stabilization of polyurethane elastomers
Xie, F., Zhang, T., Bryant, P., Kurusingal, V., Colwell, J. M., & Laycock, B. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2018.12.003 · Cited by 722
Biodegradation of plastic polymers by fungi: a brief review
Srikanth, M., Sandeep, T. S. R. S., Sucharitha, K., & Godi, S. (2022) · Bioresources and Bioprocessing · doi:10.1186/s40643-022-00532-4 · Cited by 319
Plastics degradation by hydrolytic enzymes: The plastics‐active enzymes database—PAZy
Buchholz, P. C. F., Feuerriegel, G., Zhang, H., Perez‐Garcia, P., Nover, L., Chow, J., Streit, W. R., & Pleiss, J. (2022) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.26325 · Cited by 259
Structural conformation of in vitro and in vivo aged orthodontic elastomeric modules
Eliades, T. (1999) · The European Journal of Orthodontics · doi:10.1093/ejo/21.6.649 · Cited by 115
Metadata
- Authors
- Phua, S. K., Castillo, E., Anderson, J. M., & Hiltner, A.
- Venue
- Journal of Biomedical Materials Research
- Publisher
- Wiley
- Published
- 1987-02
- Volume
- 21
- Issue
- 2
- Pages
- 231-246
- ISSN
- 0021-9304 (ISSN-L)
- 1097-4636
- OpenAlex
- W2156146422
- Cited by
- 172
- References
- 2
- FWCI
- 5.34
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Biodegradation of a polyurethane in vitro. https://app.cochat.ai/papers/10.1002/jbm.820210207
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- Phua, S. K., Castillo, E., Anderson, J. M., & Hiltner, A. (1987). Biodegradation of a polyurethane in vitro. Journal of Biomedical Materials Research. https://doi.org/10.1002/jbm.820210207
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
