The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Isolation of predominantly submicron‐sized UHMWPE wear particles from periprosthetic tissues
Abstract
A method of tissue digestion using sodium hydroxide was applied to the isolation and recovery of ultra‐high‐molecular‐weight polyethylene (UHMWPE) particles from tissues around failed total hip replacements. Density gradient ultracentrifugation of the digested tissues was performed to separate the UHMWPE from cell debris and other particulates. Fourier transform infrared spectroscopy and differential scanning calorimetry (DSC) verified that the recovered particles were UHMWPE. When viewed by scaning electron microscopy, individual particles were clearly observed and were either rounded or elongated. The majority were submicron in size. The application of this method to the study or particles from periprosthetic tissues may elucidate aspects of biomaterial particles size and shape that are important to the biologic response to, and clinical outcome of, total joint replacement. © 1995 John wiley & Sons, Inc.
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Citations
Cites
Composition and morphology of wear debris in failed uncemented total hip replacement
Shanbhag, A., Jacobs, J., Glant, T., Gilbert, J., Black, J., & Galante, J. (1994) · The Journal of Bone and Joint Surgery. British volume · doi:10.1302/0301-620x.76b1.8300684 · Cited by 387
Cited by
The role of macrophages in osteolysis of total joint replacement
Ingham, E., & Fisher, J. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.04.035 · Cited by 667
Moro, T., Takatori, Y., Ishihara, K., Konno, T., Takigawa, Y., Matsushita, T., Chung, U.-I., Nakamura, K., & Kawaguchi, H. (2004) · Nature Materials · doi:10.1038/nmat1233 · Cited by 572
Metadata
- Authors
- Campbell, P., Ma, S., Yeom, B., McKellop, H., Schmalzried, T. P., & Amstutz, H. C.
- Venue
- Journal of Biomedical Materials Research
- Publisher
- Wiley
- Published
- 1995-01
- Volume
- 29
- Issue
- 1
- Pages
- 127-131
- ISSN
- 0021-9304 (ISSN-L)
- 1097-4636
- OpenAlex
- W2130111797
- Cited by
- 352
- References
- 1
- FWCI
- 14.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Isolation of predominantly submicron‐sized UHMWPE wear particles from periprosthetic tissues. https://app.cochat.ai/papers/10.1002/jbm.820290118
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- Campbell, P., Ma, S., Yeom, B., McKellop, H., Schmalzried, T. P., & Amstutz, H. C. (1995). Isolation of predominantly submicron‐sized UHMWPE wear particles from periprosthetic tissues. Journal of Biomedical Materials Research. https://doi.org/10.1002/jbm.820290118
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
