The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Attachment and growth of cultured fibroblast cells on silk protein matrices
Abstract
The attachment and growth of L‐929 cells on films made of Bombyx mori silk proteins—fibroin and sericin and their mixtures—was studied by a cell culture method. Both cell attachment and growth were dependent on a minimum of around 90% sericin in the mixture. The results from electron micrography as well as from the DSC measurements supported the notion that the mixture of the two proteins fibroin and sericin has a phase‐separated structure in the solid state. The observed minimum of sericin in the cell attachment and growth is thought to be a result of this phase‐separated structure. Films of pure component proteins (i.e., 100% fibroin or sericin) exhibited as high a cell attachment and growth as collagen, a widely used mammalian cell culture substrate. However, a morphological study of the attached cells revealed that the cells attached to silk fibroin were extended and had a spindle shape, just like the cells attached to collagen, while the cells attached to the silk sericin had a different shape. It is concluded, therefore, that the attachment condition on silk fibroin is ideal for the viability, growth and function of the cells. © 1995 John Wiley & Sons, Inc.
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Cites
New Perspectives in Cell Adhesion: RGD and Integrins
Ruoslahti, E., & Pierschbacher, M. D. (1987) · Science · doi:10.1126/science.2821619 · Cited by 4,865
Biomedical Applications of Polymeric Materials
鶴田, 禎., Kataoka, K., & Hayashi, T. (1993) · CRC Press eBooks · Cited by 328
Physico-chemical properties of silk fibroin membrane as a biomaterial
Minoura, N., Tsukada, M., & Nagura, M. (1990) · Biomaterials · doi:10.1016/0142-9612(90)90100-5 · Cited by 312
Self-citationStimulation of clonal growth of normal fibroblasts with substrata coated with basic polymers.
McKeehan, W. L., & Ham, R. G. (1976) · The Journal of cell biology · doi:10.1083/jcb.71.3.727 · Cited by 253
Fine structure and oxygen permeability of silk fibroin membrane treated with methanol
Minoura, N., Tsukada, M., & Nagura, M. (1990) · Polymer · doi:10.1016/0032-3861(90)90117-h · Cited by 155
Self-citationDemura, M., & Asakura, T. (1989) · Biotechnology and Bioengineering · doi:10.1002/bit.260330513 · Cited by 132
In vivo blood compatibility of regenerated silk fibroin.
Sakabe, H., Ito, H., Miyamoto, T., Noishiki, Y., & Ha, W. S. (1989) · Sen'i Gakkaishi · doi:10.2115/fiber.45.11_487 · Cited by 124
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Properties of protein polymers as substratum for cell growth in vitro
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Altman, G. H., Diaz, F., Jakuba, C., Calabro, T., Horan, R. L., Chen, J., Lu, H., Richmond, J., & Kaplan, D. L. (2003) · Biomaterials · doi:10.1016/s0142-9612(02)00353-8 · Cited by 3,458
Min, B.-M., Lee, G., Kim, S. H., Nam, Y. S., Lee, T. S., & Park, W. H. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2003.08.045 · Cited by 1,151
Animal-derived products in science and current alternatives
Duarte, A. C., Costa, E. C., Filipe, H. A. L., Saraiva, S. M., Jacinto, T., Miguel, S. P., Ribeiro, M. P., & Coutinho, P. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213428 · Cited by 117
Metadata
- Authors
- Minoura, N., Aiba, S., Gotoh, Y., Tsukada, M., & Imai, Y.
- Venue
- Journal of Biomedical Materials Research
- Publisher
- Wiley
- Published
- 1995-10
- Volume
- 29
- Issue
- 10
- Pages
- 1215-1221
- ISSN
- 0021-9304 (ISSN-L)
- 1097-4636
- OpenAlex
- W2064462897
- Cited by
- 373
- References
- 9
- FWCI
- 0.67
- Type
- journal article
- Language
- en
- Open access
- closed
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- Minoura, N., Aiba, S., Gotoh, Y., Tsukada, M., & Imai, Y. (1995). Attachment and growth of cultured fibroblast cells on silk protein matrices. Journal of Biomedical Materials Research. https://doi.org/10.1002/jbm.820291008
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
